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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 22
1954 22
1955 22
1956 21
1957 10
1958 1
1963 7
1964 5
1965 7
1966 3
1967 8
1968 12
1969 5
1970 10
1971 6
1972 14
1973 12
1974 3
1975 6
1976 2
1977 8
1978 9
1979 6
1980 8
1981 12
1982 11
1983 18
1984 18
1985 17
1986 13
1987 16
1988 15
1989 21
1990 27
1991 20
1992 32
1993 22
1994 30
1995 17
1996 18
1997 45
1998 53
1999 90
2000 114
2001 93
2002 64
2003 56
2004 60
2005 80
2006 104
2007 88
2008 119
2009 91
2010 115
2011 135
2012 152
2013 163
2014 173
2015 182
2016 208
2017 229
2018 253
2019 235
2020 278
2021 307
2022 289
2023 239
2024 121

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4,118 results

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Page 1
Did you mean de pos (34,613 results)?
Pathogenesis of Autoimmune Hepatitis-Cellular and Molecular Mechanisms.
Sirbe C, Simu G, Szabo I, Grama A, Pop TL. Sirbe C, et al. Int J Mol Sci. 2021 Dec 17;22(24):13578. doi: 10.3390/ijms222413578. Int J Mol Sci. 2021. PMID: 34948375 Free PMC article. Review.
Pediatric autoimmune liver disorders include autoimmune hepatitis (AIH), autoimmune sclerosing cholangitis (ASC), and de novo AIH after liver transplantation. AIH is an idiopathic disease characterized by immune-mediated hepatocyte injury associated with the destruction of …
Pediatric autoimmune liver disorders include autoimmune hepatitis (AIH), autoimmune sclerosing cholangitis (ASC), and de novo AIH aft …
Population pharmacokinetics and exposure-response of osimertinib in patients with non-small cell lung cancer.
Brown K, Comisar C, Witjes H, Maringwa J, de Greef R, Vishwanathan K, Cantarini M, Cox E. Brown K, et al. Br J Clin Pharmacol. 2017 Jun;83(6):1216-1226. doi: 10.1111/bcp.13223. Epub 2017 Feb 6. Br J Clin Pharmacol. 2017. PMID: 28009438 Free PMC article. Clinical Trial.
AIMS: To develop a population (pop) pharmacokinetic (PK) model for osimertinib (AZD9291) and its metabolite (AZ5104) and investigate the exposure-response relationships for selected efficacy and safety parameters. METHODS: PK, safety and efficacy data were collected from t …
AIMS: To develop a population (pop) pharmacokinetic (PK) model for osimertinib (AZD9291) and its metabolite (AZ5104) and investigate …
Neuropeptides and oligopeptidases in schizophrenia.
Rodríguez B, Nani JV, Almeida PGC, Brietzke E, Lee RS, Hayashi MAF. Rodríguez B, et al. Neurosci Biobehav Rev. 2020 Jan;108:679-693. doi: 10.1016/j.neubiorev.2019.11.024. Epub 2019 Nov 30. Neurosci Biobehav Rev. 2020. PMID: 31794779 Review.
Metallic-based micro and nanostructures with antimicrobial activity.
Pop CS, Hussien MD, Popa M, Mares A, Grumezescu AM, Grigore R, Lazar V, Chifiriuc MC, Sakizlian M, Bezirtzoglou E, Bertesteanu S. Pop CS, et al. Curr Top Med Chem. 2015;15(16):1577-82. doi: 10.2174/1568026615666150414125015. Curr Top Med Chem. 2015. PMID: 25877091 Review.
Is Cerazette the minipill of choice?
[No authors listed] [No authors listed] Drug Ther Bull. 2003 Sep;41(9):68-9. doi: 10.1136/dtb.2003.41968. Drug Ther Bull. 2003. PMID: 14531209 Review.
Around 5% of women aged 16-49 years in Great Britain use a progestogen-only pill (POP; 'minipill') as contraception. These pills are used as alternatives to combined oral contraceptives (COCs), compared to which they are less reliable at preventing pregnancy: the estimated …
Around 5% of women aged 16-49 years in Great Britain use a progestogen-only pill (POP; 'minipill') as contraception. These pills are …
Prolyl oligopeptidase: a potential target for the treatment of cognitive disorders.
Männisto PT, Venäläinen J, Jalkanen A, García-Horsman JA. Männisto PT, et al. Drug News Perspect. 2007 Jun;20(5):293-305. doi: 10.1358/dnp.2007.20.5.1120216. Drug News Perspect. 2007. PMID: 17878957 Free article. Review.
Prolyl oligopeptidase (POP) is a ubiquitous post-proline cleaving enzyme that is highly expressed in brain. ...The milestones responsible for the accelerated development of POP inhibitors include the discovery that these compounds reverse memory loss in animal model …
Prolyl oligopeptidase (POP) is a ubiquitous post-proline cleaving enzyme that is highly expressed in brain. ...The milestones respons …
Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent.
Serfozo P, Wysocki J, Gulua G, Schulze A, Ye M, Liu P, Jin J, Bader M, Myöhänen T, García-Horsman JA, Batlle D. Serfozo P, et al. Hypertension. 2020 Jan;75(1):173-182. doi: 10.1161/HYPERTENSIONAHA.119.14071. Epub 2019 Dec 2. Hypertension. 2020. PMID: 31786979 Free PMC article.
In ex vivo studies, POP inhibition with ZZP reduced Ang-(1-7) formation from Ang II markedly in serum and in lung lysates. By contrast, in kidney lysates, the absence of ACE2, but not POP, obliterated Ang-(1-7) formation from added Ang II. We conclude that POP
In ex vivo studies, POP inhibition with ZZP reduced Ang-(1-7) formation from Ang II markedly in serum and in lung lysates. By contras …
Diphosphonates: history and mechanisms of action.
Fleisch H. Fleisch H. Metab Bone Dis Relat Res. 1981;3(4-5):279-87. doi: 10.1016/0221-8747(81)90044-8. Metab Bone Dis Relat Res. 1981. PMID: 6300612 Review.
Many diphosphonates have been synthesized and tested and some relationship of their structure to the spectrum of biological effects has been observed. These analogues have similar properties to pyrophosphate, but unlike pyrophosphate they are resistant to enzymic degradati …
Many diphosphonates have been synthesized and tested and some relationship of their structure to the spectrum of biological effects h …
Vessel-Targeted Chemophototherapy with Cationic Porphyrin-Phospholipid Liposomes.
Luo D, Geng J, Li N, Carter KA, Shao S, Atilla-Gokcumen GE, Lovell JF. Luo D, et al. Mol Cancer Ther. 2017 Nov;16(11):2452-2461. doi: 10.1158/1535-7163.MCT-17-0276. Epub 2017 Jul 20. Mol Cancer Ther. 2017. PMID: 28729400 Free PMC article.
Cationic liposomes have been used for targeted drug delivery to tumor blood vessels, via mechanisms that are not fully elucidated. ...Unexpectedly, empty cationic PoP liposomes (lacking Dox) induced equally potent antitumor phototherapeutic effects as the …
Cationic liposomes have been used for targeted drug delivery to tumor blood vessels, via mechanisms that are not fully elucidated. .. …
4,118 results