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Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells.
de Los Santos-Jiménez J, Campos-Sandoval JA, Márquez-Torres C, Urbano-Polo N, Brøndegaard D, Martín-Rufián M, Lobo C, Peñalver A, Gómez-García MC, Martín-Campos J, Cardona C, Castilla L, da Costa Souza F, Cheng T, Segura JA, Alonso FJ, Curi R, Colquhoun A, DeBerardinis RJ, Márquez J, Matés JM. de Los Santos-Jiménez J, et al. Among authors: deberardinis rj. J Biomed Sci. 2021 Feb 20;28(1):14. doi: 10.1186/s12929-021-00712-y. J Biomed Sci. 2021. PMID: 33610185 Free PMC article.
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Cheng T, Sudderth J, Yang C, Mullen AR, Jin ES, Matés JM, DeBerardinis RJ. Cheng T, et al. Among authors: deberardinis rj. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8674-9. doi: 10.1073/pnas.1016627108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555572 Free PMC article.
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
Marin-Valencia I, Yang C, Mashimo T, Cho S, Baek H, Yang XL, Rajagopalan KN, Maddie M, Vemireddy V, Zhao Z, Cai L, Good L, Tu BP, Hatanpaa KJ, Mickey BE, Matés JM, Pascual JM, Maher EA, Malloy CR, Deberardinis RJ, Bachoo RM. Marin-Valencia I, et al. Among authors: deberardinis rj. Cell Metab. 2012 Jun 6;15(6):827-37. doi: 10.1016/j.cmet.2012.05.001. Cell Metab. 2012. PMID: 22682223 Free PMC article.
Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells.
Martín-Rufián M, Nascimento-Gomes R, Higuero A, Crisma AR, Campos-Sandoval JA, Gómez-García MC, Cardona C, Cheng T, Lobo C, Segura JA, Alonso FJ, Szeliga M, Albrecht J, Curi R, Márquez J, Colquhoun A, Deberardinis RJ, Matés JM. Martín-Rufián M, et al. Among authors: deberardinis rj. J Mol Med (Berl). 2014 Mar;92(3):277-90. doi: 10.1007/s00109-013-1105-2. Epub 2013 Nov 26. J Mol Med (Berl). 2014. PMID: 24276018 Free PMC article.
Metabolic changes in cancer cells upon suppression of MYC.
Anso E, Mullen AR, Felsher DW, Matés JM, Deberardinis RJ, Chandel NS. Anso E, et al. Among authors: deberardinis rj. Cancer Metab. 2013 Feb 4;1(1):7. doi: 10.1186/2049-3002-1-7. Cancer Metab. 2013. PMID: 24280108 Free PMC article.
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Herranz D, Ambesi-Impiombato A, Sudderth J, Sánchez-Martín M, Belver L, Tosello V, Xu L, Wendorff AA, Castillo M, Haydu JE, Márquez J, Matés JM, Kung AL, Rayport S, Cordon-Cardo C, DeBerardinis RJ, Ferrando AA. Herranz D, et al. Among authors: deberardinis rj. Nat Med. 2015 Oct;21(10):1182-9. doi: 10.1038/nm.3955. Epub 2015 Sep 21. Nat Med. 2015. PMID: 26390244 Free PMC article.
281 results