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Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation.
Glaser S, Lam IP, Franchitto A, Gaudio E, Onori P, Chow BK, Wise C, Kopriva S, Venter J, White M, Ueno Y, Dostal D, Carpino G, Mancinelli R, Butler W, Chiasson V, DeMorrow S, Francis H, Alpini G. Glaser S, et al. Among authors: demorrow s. Hepatology. 2010 Jul;52(1):204-14. doi: 10.1002/hep.23657. Hepatology. 2010. PMID: 20578263 Free PMC article.
Biogenic amine actions on cholangiocyte function.
Demorrow S, Francis H, Alpini G. Demorrow S, et al. Exp Biol Med (Maywood). 2007 Sep;232(8):1005-13. doi: 10.3181/0703-MR-51. Exp Biol Med (Maywood). 2007. PMID: 17720946 Review.
Morphological and functional heterogeneity of the mouse intrahepatic biliary epithelium.
Glaser SS, Gaudio E, Rao A, Pierce LM, Onori P, Franchitto A, Francis HL, Dostal DE, Venter JK, DeMorrow S, Mancinelli R, Carpino G, Alvaro D, Kopriva SE, Savage JM, Alpini GD. Glaser SS, et al. Among authors: demorrow s. Lab Invest. 2009 Apr;89(4):456-69. doi: 10.1038/labinvest.2009.6. Epub 2009 Feb 9. Lab Invest. 2009. PMID: 19204666 Free PMC article.
H3 histamine receptor-mediated activation of protein kinase Calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo.
Francis H, Onori P, Gaudio E, Franchitto A, DeMorrow S, Venter J, Kopriva S, Carpino G, Mancinelli R, White M, Meng F, Vetuschi A, Sferra R, Alpini G. Francis H, et al. Among authors: demorrow s. Mol Cancer Res. 2009 Oct;7(10):1704-13. doi: 10.1158/1541-7786.MCR-09-0261. Epub 2009 Oct 13. Mol Cancer Res. 2009. PMID: 19825989 Free PMC article.
After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes.
Mancinelli R, Franchitto A, Gaudio E, Onori P, Glaser S, Francis H, Venter J, Demorrow S, Carpino G, Kopriva S, White M, Fava G, Alvaro D, Alpini G. Mancinelli R, et al. Among authors: demorrow s. Am J Pathol. 2010 Apr;176(4):1790-800. doi: 10.2353/ajpath.2010.090677. Epub 2010 Feb 25. Am J Pathol. 2010. PMID: 20185575 Free PMC article.
Activation of alpha(1) -adrenergic receptors stimulate the growth of small mouse cholangiocytes via calcium-dependent activation of nuclear factor of activated T cells 2 and specificity protein 1.
Alpini G, Franchitto A, Demorrow S, Onori P, Gaudio E, Wise C, Francis H, Venter J, Kopriva S, Mancinelli R, Carpino G, Stagnitti F, Ueno Y, Han Y, Meng F, Glaser S. Alpini G, et al. Among authors: demorrow s. Hepatology. 2011 Feb;53(2):628-39. doi: 10.1002/hep.24041. Epub 2011 Jan 3. Hepatology. 2011. PMID: 21274883 Free PMC article.
120 results