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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1948 2
1951 1
1952 1
1953 1
1954 1
1956 2
1957 2
1958 6
1959 15
1960 13
1961 6
1962 5
1963 8
1964 10
1965 10
1966 4
1967 5
1968 2
1969 3
1970 3
1971 2
1972 2
1973 2
1974 11
1975 22
1976 15
1977 26
1978 18
1979 18
1980 14
1981 8
1982 5
1983 6
1984 6
1985 6
1986 9
1987 4
1988 8
1989 3
1990 5
1991 5
1992 2
1993 2
1995 1
1996 5
1997 3
1998 4
1999 2
2000 1
2001 4
2002 7
2003 4
2004 4
2005 4
2006 1
2007 5
2008 4
2009 5
2010 4
2011 4
2012 6
2013 3
2014 4
2015 3
2016 2
2017 1
2018 3
2019 2
2020 1
2021 3
2022 5
2023 1
2024 0

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388 results

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Page 1
Determination of urinary deanol-N-oxide excretion profiles after ingestion of nutritional supplements containing deanol.
Krug O, Guddat S, Görgens C, Piper T, Möller T, Thevis M. Krug O, et al. Drug Test Anal. 2023 Nov-Dec;15(11-12):1312-1318. doi: 10.1002/dta.3580. Epub 2023 Sep 21. Drug Test Anal. 2023. PMID: 37735938
The developed test method allowed for limits of detection and quantification for deanol-N-oxide at 0.05 and 0.15 mug/mL, respectively. Urinary deanol-N-oxide c(max) levels were found between 100 and 250 mug/mL 2-5 h post-administration of 130 mg of deanol. .. …
The developed test method allowed for limits of detection and quantification for deanol-N-oxide at 0.05 and 0.15 mug/mL, respectively …
Is 2-dimethylaminoethanol (deanol) indeed a precursor of brain acetylcholine? A gas chromatographic evaluation.
Zahniser NR, Chou D, Hanin I. Zahniser NR, et al. J Pharmacol Exp Ther. 1977 Mar;200(3):545-59. J Pharmacol Exp Ther. 1977. PMID: 850128
Acute administration of deanol-p-acetamidobenzoate (Deaner; deanol) has been reported to elevate brain choline (CH) and acetylcholine (ACh) levels. We have developed a specific and sensitive gas chromatographic assay to measure deanol levels in tissue and hav …
Acute administration of deanol-p-acetamidobenzoate (Deaner; deanol) has been reported to elevate brain choline (CH) and acetyl …
Deanol and methylphenidate in minimal brain dysfunction.
Lewis JA, Young R. Lewis JA, et al. Clin Pharmacol Ther. 1975 May;17(5):534-40. doi: 10.1002/cpt1975175534. Clin Pharmacol Ther. 1975. PMID: 1092513 Clinical Trial.
Deanol, a putative acetylcholine precursor, has been used as a treatment for childhood hyperactivity for years. ...Further clinical studies on deanol are indicated....
Deanol, a putative acetylcholine precursor, has been used as a treatment for childhood hyperactivity for years. ...Further clinical s …
Dimethylaminoethanol (deanol) metabolism in rat brain and its effect on acetylcholine synthesis.
Jope RS, Jenden DJ. Jope RS, et al. J Pharmacol Exp Ther. 1979 Dec;211(3):472-9. J Pharmacol Exp Ther. 1979. PMID: 512912
In vitro [2H6]deanol was rapidly taken up by rat brain synaptosomes, but was neither methylated nor acetylated. [2H6]Deanol was a weak competitive inhibitor of the high affinity transport of [2H4]choline, thus reducing the synthesis of [2H4]acetylcholine. In vivo [2 …
In vitro [2H6]deanol was rapidly taken up by rat brain synaptosomes, but was neither methylated nor acetylated. [2H6]Deanol wa …
Deanol affects choline metabolism in peripheral tissues of mice.
Haubrich DR, Gerber NH, Pflueger AB. Haubrich DR, et al. J Neurochem. 1981 Aug;37(2):476-82. doi: 10.1111/j.1471-4159.1981.tb00480.x. J Neurochem. 1981. PMID: 7264671
Administration of 2-dimethylaminoethanol (deanol) to mice induced an increase in both the concentration and the rate of turnover of free choline in blood. ...These findings suggest that deanol increases the choline concentration in blood by inhibition of its metabol …
Administration of 2-dimethylaminoethanol (deanol) to mice induced an increase in both the concentration and the rate of turnover of f …
Neuroferritinopathy.
Chinnery PF. Chinnery PF. 2005 Apr 25 [updated 2022 Oct 20]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2005 Apr 25 [updated 2022 Oct 20]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301320 Free Books & Documents. Review.
MANAGEMENT: Treatment of manifestations: While the movement disorder is particularly resistant to conventional therapy, some response has been recorded with levodopa, tetrabenazine, orphenadrine, benzhexol, sulpiride, diazepam, clonazepam, and deanol in standard doses. Bot …
MANAGEMENT: Treatment of manifestations: While the movement disorder is particularly resistant to conventional therapy, some response has be …
Deanol acetamidobenzoate (Deaner) in tardive dyskinesia.
Stafford JR, Fann WE. Stafford JR, et al. Dis Nerv Syst. 1977 Dec;38(12 Pt 2):3-6. Dis Nerv Syst. 1977. PMID: 590063
A total of twenty-nine patients have thus far been treated with deanol in various dosage levels for periods ranging from five to thirty days. ...The failure of deanol to achieve this effect may most probably be attributed to interval after last dose, to inadequate l …
A total of twenty-nine patients have thus far been treated with deanol in various dosage levels for periods ranging from five to thir …
Deanol acetamidobenzoate inhibits the blood-brain barrier transport of choline.
Millington WR, McCall AL, Wurtman RJ. Millington WR, et al. Ann Neurol. 1978 Oct;4(4):302-6. doi: 10.1002/ana.410040403. Ann Neurol. 1978. PMID: 727735
Competition by deanol (dimethylaminoethanol) with choline for uptake from the bloodstream into the brain was demonstrated by simultaneous intracarotid administration of carbon 14-labeled choline with deanol (plus tritiated water and indium 113m, to calculate a brain …
Competition by deanol (dimethylaminoethanol) with choline for uptake from the bloodstream into the brain was demonstrated by simultan …
Deanol in the treatment of tardive dyskinesia.
Simpson GM, Voitashevsky A, Young MA, Lee JH. Simpson GM, et al. Psychopharmacology (Berl). 1977 May 9;52(3):257-61. doi: 10.1007/BF00426709. Psychopharmacology (Berl). 1977. PMID: 406628 Clinical Trial.
Ten hospitalized chronic psychotic patients with symptoms of tardive dyskinesia were given deanol and placebo, each for 8 weeks following a double-bline, crossover design. ...It was concluded that deanol may have contributed to the decline but that its effect on the …
Ten hospitalized chronic psychotic patients with symptoms of tardive dyskinesia were given deanol and placebo, each for 8 weeks follo …
388 results