Debiec-Rychter M - Search Results

1

A potent combination of the novel PI3K Inhibitor, GDC-0941, with imatinib in gastrointestinal stromal tumor xenografts: long-lasting responses after treatment withdrawal.

Floris G, Wozniak A, Sciot R, Li H, Friedman L, Van Looy T, Wellens J, Vermaelen P, Deroose CM, Fletcher JA, Debiec-Rychter M, Schöffski P. Floris G, et al. Clin Cancer Res. 2013 Feb 1;19(3):620-30. doi: 10.1158/1078-0432.CCR-12-2853. Epub 2012 Dec 11. Clin Cancer Res. 2013. PMID: 23231951 Free PMC article.

2

Rectal gastrointestinal stromal tumors associated with a novel germline KIT mutation.

Woźniak A, Rutkowski P, Sciot R, Ruka W, Michej W, Debiec-Rychter M. Woźniak A, et al. Int J Cancer. 2008 May 1;122(9):2160-4. doi: 10.1002/ijc.23338. Int J Cancer. 2008. PMID: 18183595 Free article.

3

Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.

Dewaele B, Wasag B, Cools J, Sciot R, Prenen H, Vandenberghe P, Wozniak A, Schöffski P, Marynen P, Debiec-Rychter M. Dewaele B, et al. Clin Cancer Res. 2008 Sep 15;14(18):5749-58. doi: 10.1158/1078-0432.CCR-08-0533. Clin Cancer Res. 2008. PMID: 18794084

4

High efficacy of panobinostat towards human gastrointestinal stromal tumors in a xenograft mouse model.

Floris G, Debiec-Rychter M, Sciot R, Stefan C, Fieuws S, Machiels K, Atadja P, Wozniak A, Faa G, Schöffski P. Floris G, et al. Clin Cancer Res. 2009 Jun 15;15(12):4066-76. doi: 10.1158/1078-0432.CCR-08-2588. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509176

5

Coactivated platelet-derived growth factor receptor {alpha} and epidermal growth factor receptor are potential therapeutic targets in intimal sarcoma.

Dewaele B, Floris G, Finalet-Ferreiro J, Fletcher CD, Coindre JM, Guillou L, Hogendoorn PC, Wozniak A, Vanspauwen V, Schöffski P, Marynen P, Vandenberghe P, Sciot R, Debiec-Rychter M. Dewaele B, et al. Cancer Res. 2010 Sep 15;70(18):7304-14. doi: 10.1158/0008-5472.CAN-10-1543. Epub 2010 Aug 4. Cancer Res. 2010. PMID: 20685895

6

Implications of mutational analysis for the management of patients with gastrointestinal stromal tumors and the application of targeted therapies.

Wozniak A, Floris G, Debiec-Rychter M, Sciot R, Schöffski P. Wozniak A, et al. Cancer Invest. 2010 Oct;28(8):839-48. doi: 10.3109/07357907.2010.494322. Cancer Invest. 2010. PMID: 20690803 Review.

7

The Novel HSP90 inhibitor, IPI-493, is highly effective in human gastrostrointestinal stromal tumor xenografts carrying heterogeneous KIT mutations.

Floris G, Sciot R, Wozniak A, Van Looy T, Wellens J, Faa G, Normant E, Debiec-Rychter M, Schöffski P. Floris G, et al. Clin Cancer Res. 2011 Sep 1;17(17):5604-14. doi: 10.1158/1078-0432.CCR-11-0562. Epub 2011 Jul 7. Clin Cancer Res. 2011. PMID: 21737509

8

The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage, and cell proliferation arrest in xenograft models of gastrointestinal stromal tumors.

Floris G, Debiec-Rychter M, Wozniak A, Stefan C, Normant E, Faa G, Machiels K, Vanleeuw U, Sciot R, Schöffski P. Floris G, et al. Mol Cancer Ther. 2011 Oct;10(10):1897-908. doi: 10.1158/1535-7163.MCT-11-0148. Epub 2011 Aug 8. Mol Cancer Ther. 2011. PMID: 21825009

9

Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis.

Quattrone A, Dewaele B, Wozniak A, Bauters M, Vanspauwen V, Floris G, Schöffski P, Chibon F, Coindre JM, Sciot R, Debiec-Rychter M. Quattrone A, et al. J Pathol. 2012 Dec;228(4):565-74. doi: 10.1002/path.4071. Epub 2012 Sep 28. J Pathol. 2012. PMID: 22786615

10

Unbiased compound screening identifies unexpected drug sensitivities and novel treatment options for gastrointestinal stromal tumors.

Boichuk S, Lee DJ, Mehalek KR, Makielski KR, Wozniak A, Seneviratne DS, Korzeniewski N, Cuevas R, Parry JA, Brown MF, Zewe J, Taguchi T, Kuan SF, Schöffski P, Debiec-Rychter M, Duensing A. Boichuk S, et al. Cancer Res. 2014 Feb 15;74(4):1200-13. doi: 10.1158/0008-5472.CAN-13-1955. Epub 2014 Jan 2. Cancer Res. 2014. PMID: 24385214

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