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Application of an innovative design space optimization strategy to the development of liquid chromatographic methods to combat potentially counterfeit nonsteroidal anti-inflammatory drugs.
Mbinze JK, Lebrun P, Debrus B, Dispas A, Kalenda N, Mavar Tayey Mbay J, Schofield T, Boulanger B, Rozet E, Hubert P, Marini RD. Mbinze JK, et al. Among authors: debrus b. J Chromatogr A. 2012 Nov 9;1263:113-24. doi: 10.1016/j.chroma.2012.09.038. Epub 2012 Sep 20. J Chromatogr A. 2012. PMID: 23046622
Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography.
Debrus B, Lebrun P, Ceccato A, Caliaro G, Rozet E, Nistor I, Oprean R, Rupérez FJ, Barbas C, Boulanger B, Hubert P. Debrus B, et al. Anal Chim Acta. 2011 Apr 8;691(1-2):33-42. doi: 10.1016/j.aca.2011.02.035. Epub 2011 Feb 23. Anal Chim Acta. 2011. PMID: 21458628
Peak detection and peak matching were carried out with a previously developed methodology using independent component analysis published by B. Debrus et al. in 2009. The present successful applications strengthen the high potential of these methodologies for the aut …
Peak detection and peak matching were carried out with a previously developed methodology using independent component analysis published by …
Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments, independent component analysis and design space.
Debrus B, Lebrun P, Kindenge JM, Lecomte F, Ceccato A, Caliaro G, Mbay JM, Boulanger B, Marini RD, Rozet E, Hubert P. Debrus B, et al. J Chromatogr A. 2011 Aug 5;1218(31):5205-15. doi: 10.1016/j.chroma.2011.05.102. Epub 2011 Jun 12. J Chromatogr A. 2011. PMID: 21705006
Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material.
De Backer B, Debrus B, Lebrun P, Theunis L, Dubois N, Decock L, Verstraete A, Hubert P, Charlier C. De Backer B, et al. Among authors: debrus b. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Dec 15;877(32):4115-24. doi: 10.1016/j.jchromb.2009.11.004. Epub 2009 Nov 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19932642
Application of design of experiments and design space methodology for the HPLC-UV separation optimization of aporphine alkaloids from leaves of Spirospermum penduliflorum Thouars.
Rafamantanana MH, Debrus B, Raoelison GE, Rozet E, Lebrun P, Uverg-Ratsimamanga S, Hubert P, Quetin-Leclercq J. Rafamantanana MH, et al. Among authors: debrus b. J Pharm Biomed Anal. 2012 Mar 25;62:23-32. doi: 10.1016/j.jpba.2011.12.028. Epub 2012 Jan 25. J Pharm Biomed Anal. 2012. PMID: 22310553
24 results