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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1969 1
1973 1
1976 1
1977 1
1979 1
1980 1
1981 1
1982 1
1983 2
1984 2
1985 2
1986 3
1988 2
1989 1
1990 2
1991 3
1992 3
1993 2
1995 2
1996 2
1998 1
1999 1
2000 1
2001 2
2002 1
2005 1
2007 2
2008 3
2011 3
2012 1
2013 3
2014 2
2015 4
2016 3
2017 1
2018 6
2019 4
2020 11
2021 6
2022 17
2023 8
2024 4

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116 results

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Page 1
Assessing the causal association between human blood metabolites and the risk of epilepsy.
Cai J, Li X, Wu S, Tian Y, Zhang Y, Wei Z, Jin Z, Li X, Chen X, Chen WX. Cai J, et al. J Transl Med. 2022 Sep 30;20(1):437. doi: 10.1186/s12967-022-03648-5. J Transl Med. 2022. PMID: 36180952 Free PMC article.
Only four metabolites remained significant associations with epilepsy when combined with the FinnGen consortium [uridine: odds ratio (OR) = 2.34, 95% confidence interval (CI) = 1.48-3.71, P = 0.0003; 2-hydroxystearate: OR = 1.61, 95% CI = 1.19-2.18, P = 0.002; decanoylcarnitin
Only four metabolites remained significant associations with epilepsy when combined with the FinnGen consortium [uridine: odds ratio (OR) = …
Serum lipidome unravels a diagnostic potential in bile acid diarrhoea.
Lewinska M, Kårhus ML, Ellegaard AG, Romero-Gómez M, Macias RIR, Andersen JB, Knop FK. Lewinska M, et al. Gut. 2023 Sep;72(9):1698-1708. doi: 10.1136/gutjnl-2022-329213. Epub 2023 Apr 18. Gut. 2023. PMID: 37072179 Free PMC article.
We detected 70 metabolites with a discriminatory performance in the discovery set with an area under receiver-operating curve metric above 0.80. Logistic regression modelling using concentrations of decanoylcarnitine, cholesterol ester (22:5), eicosatrienoic acid, L-alpha- …
We detected 70 metabolites with a discriminatory performance in the discovery set with an area under receiver-operating curve metric above 0 …
Medium-Chain Acylcarnitines Are Associated With Cardioembolic Stroke and Stroke Recurrence.
Seo WK, Jo G, Shin MJ, Oh K. Seo WK, et al. Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2245-2253. doi: 10.1161/ATVBAHA.118.311373. Arterioscler Thromb Vasc Biol. 2018. PMID: 30026276 Free article.
We obtained 29 metabolomics signatures, and of these, 2 medium-chain acylcarnitines (decanoylcarnitine and octanoylcarnitine) were selected as independent discriminants for CE (odds ratio, 2.839; 95% CI, 1.241-6.493 for decanoylcarnitine; odds ratio, 2.839; 95% CI, …
We obtained 29 metabolomics signatures, and of these, 2 medium-chain acylcarnitines (decanoylcarnitine and octanoylcarnitine) were se …
The Association Between Acylcarnitine Metabolites and Cardiovascular Disease in Chinese Patients With Type 2 Diabetes Mellitus.
Zhao S, Feng XF, Huang T, Luo HH, Chen JX, Zeng J, Gu M, Li J, Sun XY, Sun D, Yang X, Fang ZZ, Cao YF. Zhao S, et al. Front Endocrinol (Lausanne). 2020 May 5;11:212. doi: 10.3389/fendo.2020.00212. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32431666 Free PMC article.
Factor 1 consisted of acetylcarnitine, butyrylcarnitine, hydroxylbutyrylcarnitine, glutarylcarnitine, hexanoylcarnitine, octanoylcarnitine, and tetradecanoyldiacylcarnitine. Factor 2 consisted of decanoylcarnitine, lauroylcarnitine, myristoylcarnitine, 3-hydroxyl-tetradeca …
Factor 1 consisted of acetylcarnitine, butyrylcarnitine, hydroxylbutyrylcarnitine, glutarylcarnitine, hexanoylcarnitine, octanoylcarnitine, …
Multi-omics reveals specific host metabolism-microbiome associations in intracerebral hemorrhage.
Chen L, Wang S, Zhang Y, Li Y, Zhang X, Ma J, Zou X, Yao T, Li S, Chen J, Zhou H, Wu L, Zhou Y, Zhang L. Chen L, et al. Front Cell Infect Microbiol. 2022 Dec 22;12:999627. doi: 10.3389/fcimb.2022.999627. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36619742 Free PMC article.
Serum untargeted metabolomic analysis combined with ROC curves showed that octanoylcarnitine, decanoylcarnitine, dodecanoylcarnitine, glyceric acid, pyruvic acid, aspartic acid, methylcysteine, pyroglutamic acid, 9E-tetradecenoic acid, N-Acetylneuraminic acid, and aconitic …
Serum untargeted metabolomic analysis combined with ROC curves showed that octanoylcarnitine, decanoylcarnitine, dodecanoylcarnitine, …
Identification of Biomarkers for Preeclampsia Based on Metabolomics.
Yao M, Xiao Y, Yang Z, Ge W, Liang F, Teng H, Gu Y, Yin J. Yao M, et al. Clin Epidemiol. 2022 Mar 19;14:337-360. doi: 10.2147/CLEP.S353019. eCollection 2022. Clin Epidemiol. 2022. PMID: 35342309 Free PMC article. Review.
Several metabolites, such as creatinine, glycine, L-isoleucine, and glucose and biomarkers with consistent trends (decanoylcarnitine, 3-hydroxyisovaleric acid, and octenoylcarnitine), were frequently reported. ...
Several metabolites, such as creatinine, glycine, L-isoleucine, and glucose and biomarkers with consistent trends (decanoylcarnitine, …
High-Performance Liquid Chromatography-Mass Spectrometry-based Metabolic Profiling of Adult Growth Hormone Deficiency.
Yang H, Chen M, Wang Y, Jiang L, Wang L, Duan L, Gong F, Zhu H, Pan H. Yang H, et al. J Clin Endocrinol Metab. 2023 Aug 18;108(9):2272-2281. doi: 10.1210/clinem/dgad129. J Clin Endocrinol Metab. 2023. PMID: 36883594
During rhGH treatment, there was a statistically significant negative correlation between deoxycholic acid glycine conjugate and waist-to-hip ratio, while a statistically significant positive correlation existed between decanoylcarnitine and serum low-density lipoprotein l …
During rhGH treatment, there was a statistically significant negative correlation between deoxycholic acid glycine conjugate and waist-to-hi …
Untargeted LC/MS-Based Metabolic Phenotyping of Hypopituitarism in Young Males.
Zhang Y, Sun S, Wang M, Yu W, Chen P, Yuan F, Fang X. Zhang Y, et al. Front Pharmacol. 2021 Jul 8;12:684869. doi: 10.3389/fphar.2021.684869. eCollection 2021. Front Pharmacol. 2021. PMID: 34305597 Free PMC article.
Furthermore, the creatine/creatinine and decanoylcarnitine/carnitine ratio were identified as diagnostic biomarkers for Hypo-Pit with AUCs of 0.976 and 0.988, respectively. Finally, we found that the creatinine and decanoylcarnitine/carnitine ratio could distinguish …
Furthermore, the creatine/creatinine and decanoylcarnitine/carnitine ratio were identified as diagnostic biomarkers for Hypo-Pit with …
Decanoylcarnitine Inhibits Triple-Negative Breast Cancer Progression via Mmp9 in an Intermittent Fasting Obesity Mouse.
Tang Y, Chen S, Wang S, Xu K, Zhang K, Wang D, Feng N. Tang Y, et al. Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241233443. doi: 10.1177/15330338241233443. Technol Cancer Res Treat. 2024. PMID: 38409962 Free PMC article.
Further investigations confirmed that decanoylcarnitine could inhibit Mmp9 expression in TNBC cells, primary tumors, lung, and liver metastasis tissues. Mmp9 overexpression abolished the inhibitory effect of decanoylcarnitine on cell migration. Conclusion: This stud …
Further investigations confirmed that decanoylcarnitine could inhibit Mmp9 expression in TNBC cells, primary tumors, lung, and liver …
Acute reversal of experimental diabetic ketoacidosis in the rat with (+)-decanoylcarnitine.
McGarry JD, Foster DW. McGarry JD, et al. J Clin Invest. 1973 Apr;52(4):877-84. doi: 10.1172/JCI107252. J Clin Invest. 1973. PMID: 4632691 Free PMC article.
In vitro the inhibitor caused an almost complete block in ketone body production. In vivo (+)-decanoylcarnitine caused a rapid reversal of ketosis under conditions where large doses of insulin had little effect. ...Studies in the isolated perfused liver indicated that the …
In vitro the inhibitor caused an almost complete block in ketone body production. In vivo (+)-decanoylcarnitine caused a rapid revers …
116 results