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Investigation of manic and euthymic episodes identifies state- and trait-specific gene expression and STAB1 as a new candidate gene for bipolar disorder.
Witt SH, Juraeva D, Sticht C, Strohmaier J, Meier S, Treutlein J, Dukal H, Frank J, Lang M, Deuschle M, Schulze TG, Degenhardt F, Mattheisen M, Brors B, Cichon S, Nöthen MM, Witt CC, Rietschel M. Witt SH, et al. Among authors: degenhardt f. Transl Psychiatry. 2014 Aug 19;4(8):e426. doi: 10.1038/tp.2014.71. Transl Psychiatry. 2014. PMID: 25136889 Free PMC article.
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
Andlauer TFM, Guzman-Parra J, Streit F, Strohmaier J, González MJ, Gil Flores S, Cabaleiro Fabeiro FJ, Del Río Noriega F, Perez FP, Haro González J, Orozco Diaz G, de Diego-Otero Y, Moreno-Küstner B, Auburger G, Degenhardt F, Heilmann-Heimbach S, Herms S, Hoffmann P, Frank J, Foo JC, Treutlein J, Witt SH, Cichon S, Kogevinas M; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Rivas F, Mayoral F, Müller-Myhsok B, Forstner AJ, Nöthen MM, Rietschel M. Andlauer TFM, et al. Among authors: degenhardt f. Mol Psychiatry. 2021 Apr;26(4):1286-1298. doi: 10.1038/s41380-019-0558-2. Epub 2019 Nov 11. Mol Psychiatry. 2021. PMID: 31712721 Free PMC article.
Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder.
Priebe L, Degenhardt FA, Herms S, Haenisch B, Mattheisen M, Nieratschker V, Weingarten M, Witt S, Breuer R, Paul T, Alblas M, Moebus S, Lathrop M, Leboyer M, Schreiber S, Grigoroiu-Serbanescu M, Maier W, Propping P, Rietschel M, Nöthen MM, Cichon S, Mühleisen TW. Priebe L, et al. Among authors: degenhardt fa. Mol Psychiatry. 2012 Apr;17(4):421-32. doi: 10.1038/mp.2011.8. Epub 2011 Mar 1. Mol Psychiatry. 2012. PMID: 21358712
Studies in humans and mice implicate neurocan in the etiology of mania.
Miró X, Meier S, Dreisow ML, Frank J, Strohmaier J, Breuer R, Schmäl C, Albayram Ö, Pardo-Olmedilla MT, Mühleisen TW, Degenhardt FA, Mattheisen M, Reinhard I, Bilkei-Gorzo A, Cichon S, Seidenbecher C, Rietschel M, Nöthen MM, Zimmer A. Miró X, et al. Am J Psychiatry. 2012 Sep;169(9):982-90. doi: 10.1176/appi.ajp.2012.11101585. Am J Psychiatry. 2012. PMID: 22952076
Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype.
Breuer R, Hamshere ML, Strohmaier J, Mattheisen M, Degenhardt F, Meier S, Paul T, O'Donovan MC, Mühleisen TW, Schulze TG, Nöthen MM, Cichon S, Craddock N, Rietschel M. Breuer R, et al. Among authors: degenhardt f. Mol Psychiatry. 2011 Jun;16(6):587-9. doi: 10.1038/mp.2010.67. Epub 2010 Jun 15. Mol Psychiatry. 2011. PMID: 20548298 No abstract available.
Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study.
Hammer C, Cichon S, Mühleisen TW, Haenisch B, Degenhardt F, Mattheisen M, Breuer R, Witt SH, Strohmaier J, Oruc L, Rivas F, Babadjanova G, Grigoroiu-Serbanescu M, Hauser J, Röth R, Rappold G, Rietschel M, Nöthen MM, Niesler B. Hammer C, et al. Among authors: degenhardt f. Transl Psychiatry. 2012 Apr 17;2(4):e103. doi: 10.1038/tp.2012.30. Transl Psychiatry. 2012. PMID: 22832903 Free PMC article.
Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.
Meier S, Mattheisen M, Vassos E, Strohmaier J, Treutlein J, Josef F, Breuer R, Degenhardt F, Mühleisen TW, Müller-Myhsok B, Steffens M, Schmael C, McMahon FJ; Bipolar Disorder Genome Study (BiGS) Consortium; Nöthen MM, Cichon S, Schulze TG, Rietschel M, Kelsoe JR, Greenwood TA, Nievergelt CM, Barrett TB, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger J, Edenberg HJ, Foroud T, Koller DL, Gershon ES, Liu CY, Badner JA, Scheftner W, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon F, Chen DT, Schulze TG, Berrettini W, Potash JB, Zandi PP, Mahon PB, McInnis M, Craig D, Szelinger S. Meier S, et al. Among authors: degenhardt f. Transl Psychiatry. 2012 Sep 25;2(9):e165. doi: 10.1038/tp.2012.81. Transl Psychiatry. 2012. PMID: 23010768 Free PMC article.
Duplications in RB1CC1 are associated with schizophrenia; identification in large European sample sets.
Degenhardt F, Priebe L, Meier S, Lennertz L, Streit F, Witt SH, Hofmann A, Becker T, Mössner R, Maier W, Nenadic I, Sauer H, Mattheisen M, Buizer-Voskamp J, Ophoff RA; GROUP Consortium; Rujescu D, Giegling I, Ingason A, Wagner M, Delobel B, Andrieux J, Meyer-Lindenberg A, Heinz A, Walter H, Moebus S, Corvin A; Wellcome Trust Case Control Consortium 2, International Schizophrenia Consortium; Rietschel M, Nöthen MM, Cichon S. Degenhardt F, et al. Transl Psychiatry. 2013 Nov 26;3(11):e326. doi: 10.1038/tp.2013.101. Transl Psychiatry. 2013. PMID: 26151896 Free PMC article.
High loading of polygenic risk in cases with chronic schizophrenia.
Meier SM, Agerbo E, Maier R, Pedersen CB, Lang M, Grove J, Hollegaard MV, Demontis D, Trabjerg BB, Hjorthøj C, Ripke S, Degenhardt F, Nöthen MM, Rujescu D, Maier W; MooDS SCZ Consortium; Werge T, Mors O, Hougaard DM, Børglum AD, Wray NR, Rietschel M, Nordentoft M, Mortensen PB, Mattheisen M. Meier SM, et al. Among authors: degenhardt f. Mol Psychiatry. 2016 Jul;21(7):969-74. doi: 10.1038/mp.2015.130. Epub 2015 Sep 1. Mol Psychiatry. 2016. PMID: 26324100
357 results