Dehne EM - Search Results

1

Autologous induced pluripotent stem cell-derived four-organ-chip.

Ramme AP, Koenig L, Hasenberg T, Schwenk C, Magauer C, Faust D, Lorenz AK, Krebs AC, Drewell C, Schirrmann K, Vladetic A, Lin GC, Pabinger S, Neuhaus W, Bois F, Lauster R, Marx U, Dehne EM. Ramme AP, et al. Among authors: dehne em. Future Sci OA. 2019 Sep 10;5(8):FSO413. doi: 10.2144/fsoa-2019-0065. Future Sci OA. 2019. PMID: 31534781 Free PMC article.

2

Validation of Bioreactor and Human-on-a-Chip Devices for Chemical Safety Assessment.

Rebelo SP, Dehne EM, Brito C, Horland R, Alves PM, Marx U. Rebelo SP, et al. Among authors: dehne em. Adv Exp Med Biol. 2016;856:299-316. doi: 10.1007/978-3-319-33826-2_12. Adv Exp Med Biol. 2016. PMID: 27671728 Review.

3

Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2.

Hiller T, Röhrs V, Dehne EM, Wagner A, Fechner H, Lauster R, Kurreck J. Hiller T, et al. Among authors: dehne em. J Vis Exp. 2016 Oct 24;(116):54633. doi: 10.3791/54633. J Vis Exp. 2016. PMID: 27805597 Free PMC article.

4

The ascendance of microphysiological systems to solve the drug testing dilemma.

Dehne EM, Hasenberg T, Marx U. Dehne EM, et al. Future Sci OA. 2017 Mar 31;3(2):FSO185. doi: 10.4155/fsoa-2017-0002. eCollection 2017 Jun. Future Sci OA. 2017. PMID: 28670475 Free PMC article. Review.

5

Human multi-organ chip co-culture of bronchial lung culture and liver spheroids for substance exposure studies.

Schimek K, Frentzel S, Luettich K, Bovard D, Rütschle I, Boden L, Rambo F, Erfurth H, Dehne EM, Winter A, Marx U, Hoeng J. Schimek K, et al. Among authors: dehne em. Sci Rep. 2020 May 12;10(1):7865. doi: 10.1038/s41598-020-64219-6. Sci Rep. 2020. PMID: 32398725 Free PMC article.

6

Organ-on-a-chip: Determine feasibility of a human liver microphysiological model to assess long-term steroid metabolites in sports drug testing.

Görgens C, Ramme AP, Guddat S, Schrader Y, Winter A, Dehne EM, Horland R, Thevis M. Görgens C, et al. Among authors: dehne em. Drug Test Anal. 2021 Nov;13(11-12):1921-1928. doi: 10.1002/dta.3161. Epub 2021 Sep 22. Drug Test Anal. 2021. PMID: 34505743

7

An Individual Patient's "Body" on Chips-How Organismoid Theory Can Translate Into Your Personal Precision Therapy Approach.

Marx U, Accastelli E, David R, Erfurth H, Koenig L, Lauster R, Ramme AP, Reinke P, Volk HD, Winter A, Dehne EM. Marx U, et al. Among authors: dehne em. Front Med (Lausanne). 2021 Sep 13;8:728866. doi: 10.3389/fmed.2021.728866. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34589503 Free PMC article.

8

A Human Stem Cell-Derived Brain-Liver Chip for Assessing Blood-Brain-Barrier Permeation of Pharmaceutical Drugs.

Koenig L, Ramme AP, Faust D, Mayer M, Flötke T, Gerhartl A, Brachner A, Neuhaus W, Appelt-Menzel A, Metzger M, Marx U, Dehne EM. Koenig L, et al. Among authors: dehne em. Cells. 2022 Oct 19;11(20):3295. doi: 10.3390/cells11203295. Cells. 2022. PMID: 36291161 Free PMC article.

9

Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery.

Ewart L, Dehne EM, Fabre K, Gibbs S, Hickman J, Hornberg E, Ingelman-Sundberg M, Jang KJ, Jones DR, Lauschke VM, Marx U, Mettetal JT, Pointon A, Williams D, Zimmermann WH, Newham P. Ewart L, et al. Among authors: dehne em. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:65-82. doi: 10.1146/annurev-pharmtox-010617-052722. Epub 2017 Oct 13. Annu Rev Pharmacol Toxicol. 2018. PMID: 29029591 Review.

10

Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development.

Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A. Marx U, et al. Among authors: dehne em. ALTEX. 2020;37(3):365-394. doi: 10.14573/altex.2001241. Epub 2020 Feb 28. ALTEX. 2020. PMID: 32113184 Free PMC article.

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