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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1936 2
1940 1
1941 1
1942 1
1943 1
1944 3
1945 3
1946 4
1947 3
1948 6
1949 1
1950 9
1951 14
1952 12
1953 7
1954 12
1955 8
1956 15
1957 4
1958 8
1959 6
1960 7
1961 9
1962 7
1963 5
1964 11
1965 10
1966 6
1967 8
1968 4
1969 4
1970 10
1971 6
1972 6
1973 5
1974 4
1975 23
1976 14
1977 13
1978 11
1979 22
1980 17
1981 19
1982 12
1983 20
1984 26
1985 25
1986 31
1987 30
1988 15
1989 27
1990 20
1991 40
1992 27
1993 30
1994 34
1995 40
1996 35
1997 44
1998 62
1999 44
2000 51
2001 53
2002 50
2003 44
2004 53
2005 49
2006 33
2007 34
2008 41
2009 31
2010 37
2011 40
2012 41
2013 49
2014 48
2015 43
2016 48
2017 47
2018 39
2019 37
2020 43
2021 43
2022 47
2023 45
2024 15

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1,841 results

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Page 1
Topical L-ascorbic acid: percutaneous absorption studies.
Pinnell SR, Yang H, Omar M, Monteiro-Riviere N, DeBuys HV, Walker LC, Wang Y, Levine M. Pinnell SR, et al. Dermatol Surg. 2001 Feb;27(2):137-42. doi: 10.1046/j.1524-4725.2001.00264.x. Dermatol Surg. 2001. PMID: 11207686
METHODS: L-ascorbic acid or its derivatives were applied to pig skin. Skin levels of L-ascorbic acid were measured to determine percutaneous delivery. ...Tissue levels were saturated after three daily applications; the half-life of tissue disappearance was about 4 d …
METHODS: L-ascorbic acid or its derivatives were applied to pig skin. Skin levels of L-ascorbic acid were measured to determin …
Dehydroascorbate reduction.
Wells WW, Xu DP. Wells WW, et al. J Bioenerg Biomembr. 1994 Aug;26(4):369-77. doi: 10.1007/BF00762777. J Bioenerg Biomembr. 1994. PMID: 7844111 Review.
Dehydroascorbic acid is generated in plants and animal cells by oxidation of ascorbic acid. The reaction is believed to occur by the one-electron oxidation of ascorbic acid to semidehydroascorbate radical followed by disproportionation to dehydroasc …
Dehydroascorbic acid is generated in plants and animal cells by oxidation of ascorbic acid. The reaction is believed to …
Dehydroascorbic acid.
Deutsch JC. Deutsch JC. J Chromatogr A. 2000 Jun 9;881(1-2):299-307. doi: 10.1016/s0021-9673(00)00166-7. J Chromatogr A. 2000. PMID: 10905713 Review.
Dehydroascorbic acid (DHA) is an important, interesting but somewhat enigmatic compound in biological systems. DHA has many unique properties that set it apart from ascorbic acid (AA), and DHA has functions that may be very important beyond that in the AA:DHA …
Dehydroascorbic acid (DHA) is an important, interesting but somewhat enigmatic compound in biological systems. DHA has many un …
Dehydroascorbic acid as an anti-cancer agent.
Toohey JI. Toohey JI. Cancer Lett. 2008 May 18;263(2):164-9. doi: 10.1016/j.canlet.2008.02.002. Epub 2008 Apr 2. Cancer Lett. 2008. PMID: 18378072 Review.
Three discoveries together point the way to a potential treatment for cancer. In 1982, Poydock and colleagues found that dehydroascorbic acid has the remarkable ability to eliminate the aggressive mouse tumours, L1210, P388, Krebs sarcoma, and Ehrlich carcinoma. ... …
Three discoveries together point the way to a potential treatment for cancer. In 1982, Poydock and colleagues found that dehydroascorbic …
Dehydroascorbic acid sensitizes cancer cells to system x(c)(-) inhibition-induced ferroptosis by promoting lipid droplet peroxidation.
Ferrada L, Barahona MJ, Vera M, Stockwell BR, Nualart F. Ferrada L, et al. Cell Death Dis. 2023 Sep 27;14(9):637. doi: 10.1038/s41419-023-06153-9. Cell Death Dis. 2023. PMID: 37752118 Free PMC article.
Here, we discovered that co-treatment with the metabolically stable ferroptosis inducer imidazole ketone erastin (IKE) and the oxidized form of vitamin C, dehydroascorbic acid (DHAA), is a powerful therapy that induces ferroptosis in tumor cells previously resistant …
Here, we discovered that co-treatment with the metabolically stable ferroptosis inducer imidazole ketone erastin (IKE) and the oxidized form …
Metabolic control by dehydroascorbic acid: Questions and controversies in cancer cells.
Ferrada L, Salazar K, Nualart F. Ferrada L, et al. J Cell Physiol. 2019 Nov;234(11):19331-19338. doi: 10.1002/jcp.28637. Epub 2019 Apr 8. J Cell Physiol. 2019. PMID: 30963581 Review.
From Linus Pauling's studies in 1976, it was proposed that ascorbic acid (AA) could selectively kill tumor cells. However, further research suggested that vitamin C has no effect on tumor survival. In the last decade, new and emerging functions for vitamin C have been disc …
From Linus Pauling's studies in 1976, it was proposed that ascorbic acid (AA) could selectively kill tumor cells. However, further re …
Regulation of vitamin C transport.
Wilson JX. Wilson JX. Annu Rev Nutr. 2005;25:105-25. doi: 10.1146/annurev.nutr.25.050304.092647. Annu Rev Nutr. 2005. PMID: 16011461 Review.
Ascorbic acid and dehydroascorbic acid (DHAA, oxidized vitamin C) are dietary sources of vitamin C in humans. ...Concerning flux across the plasma membrane, simple diffusion of ascorbic acid plays only a small or negligible role. More important are spe …
Ascorbic acid and dehydroascorbic acid (DHAA, oxidized vitamin C) are dietary sources of vitamin C in humans. ...Concer …
Ascorbic acid and dehydroascorbic acid interconversion without net oxidation or reduction.
Deutsch JC. Deutsch JC. Anal Biochem. 1997 Apr 5;247(1):58-62. doi: 10.1006/abio.1997.2035. Anal Biochem. 1997. PMID: 9126371
The interconversion of ascorbic acid and dehydroascorbic acid was examined in aqueous solution using unlabeled dehydroascorbic acid and nonlabile, stable isotope-labeled ascorbic acid by gas chromatographic/mass spectrometric analysis. Al …
The interconversion of ascorbic acid and dehydroascorbic acid was examined in aqueous solution using unlabeled dehyd …
l-Dehydroascorbic acid recycled by thiols efficiently scavenges non-thermal plasma-induced hydroxyl radicals.
Okazaki Y, Tanaka H, Hori M, Toyokuni S. Okazaki Y, et al. Arch Biochem Biophys. 2019 Jul 15;669:87-95. doi: 10.1016/j.abb.2019.05.019. Epub 2019 May 31. Arch Biochem Biophys. 2019. PMID: 31153952
Here we quantitated hydroxyl radicals, a major reactive oxygen species generated after NTP exposure, by electron paramagnetic resonance (EPR) spectroscopy using two distinct spin-trapping probes, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) and 3,3,5,5-tetramethyl-1-pyrroline-N-oxide …
Here we quantitated hydroxyl radicals, a major reactive oxygen species generated after NTP exposure, by electron paramagnetic resonance (EPR …
Ascorbic acid leads to glycation and interferes with neurite outgrowth.
Scheffler J, Bork K, Bezold V, Rosenstock P, Gnanapragassam VS, Horstkorte R. Scheffler J, et al. Exp Gerontol. 2019 Mar;117:25-30. doi: 10.1016/j.exger.2018.08.005. Epub 2018 Aug 24. Exp Gerontol. 2019. PMID: 30149062
Ascorbic acid can be reversibly oxidized in two steps, leading to semidehydroascorbic acid and dehydroascorbic acid, respectively. ...We found that both applications of ascorbic acid or dehydroascorbic acid leads to glycation of ce …
Ascorbic acid can be reversibly oxidized in two steps, leading to semidehydroascorbic acid and dehydroascorbic acid …
1,841 results