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Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.
Staudt V, Bothur E, Klein M, Lingnau K, Reuter S, Grebe N, Gerlitzki B, Hoffmann M, Ulges A, Taube C, Dehzad N, Becker M, Stassen M, Steinborn A, Lohoff M, Schild H, Schmitt E, Bopp T. Staudt V, et al. Among authors: dehzad n. Immunity. 2010 Aug 27;33(2):192-202. doi: 10.1016/j.immuni.2010.07.014. Epub 2010 Jul 30. Immunity. 2010. PMID: 20674401 Free article.
The tick salivary protein sialostatin L inhibits the Th9-derived production of the asthma-promoting cytokine IL-9 and is effective in the prevention of experimental asthma.
Horka H, Staudt V, Klein M, Taube C, Reuter S, Dehzad N, Andersen JF, Kopecky J, Schild H, Kotsyfakis M, Hoffmann M, Gerlitzki B, Stassen M, Bopp T, Schmitt E. Horka H, et al. Among authors: dehzad n. J Immunol. 2012 Mar 15;188(6):2669-76. doi: 10.4049/jimmunol.1100529. Epub 2012 Feb 10. J Immunol. 2012. PMID: 22327077 Free PMC article.
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