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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1977 2
1979 2
1980 3
1981 3
1982 1
1983 1
1984 3
1985 5
1986 3
1987 3
1988 4
1989 6
1990 3
1991 4
1992 10
1993 6
1994 6
1995 6
1996 5
1997 5
1998 7
1999 5
2000 13
2001 9
2002 7
2003 18
2004 12
2005 7
2006 14
2007 18
2008 10
2009 20
2010 15
2011 23
2012 24
2013 23
2014 36
2015 42
2016 34
2017 40
2018 24
2019 42
2020 31
2021 38
2022 29
2023 18
2024 17

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581 results

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Page 1
Development of mRNA manufacturing for vaccines and therapeutics: mRNA platform requirements and development of a scalable production process to support early phase clinical trials.
Whitley J, Zwolinski C, Denis C, Maughan M, Hayles L, Clarke D, Snare M, Liao H, Chiou S, Marmura T, Zoeller H, Hudson B, Peart J, Johnson M, Karlsson A, Wang Y, Nagle C, Harris C, Tonkin D, Fraser S, Capiz L, Zeno CL, Meli Y, Martik D, Ozaki DA, Caparoni A, Dickens JE, Weissman D, Saunders KO, Haynes BF, Sempowski GD, Denny TN, Johnson MR. Whitley J, et al. Transl Res. 2022 Apr;242:38-55. doi: 10.1016/j.trsl.2021.11.009. Epub 2021 Dec 4. Transl Res. 2022. PMID: 34871810 Free PMC article. Review.
We also have demonstrated the products produced at manufacturing scale under such approaches display good potency and protection in relevant animal models with mRNA products encoding both vaccine immunogens and antibodies. ...
We also have demonstrated the products produced at manufacturing scale under such approaches display good potency and protection in r …
Cataract.
Lam D, Rao SK, Ratra V, Liu Y, Mitchell P, King J, Tassignon MJ, Jonas J, Pang CP, Chang DF. Lam D, et al. Nat Rev Dis Primers. 2015 Jun 11;1:15014. doi: 10.1038/nrdp.2015.14. Nat Rev Dis Primers. 2015. PMID: 27188414 Review.
Phacoemulsification is the gold standard for cataract surgery in the developed world, whereas manual small incision cataract surgery is used frequently in developing countries. In general, the outcomes of surgery are good and complications, such as endophthalmitis, often c …
Phacoemulsification is the gold standard for cataract surgery in the developed world, whereas manual small incision cataract surgery is used …
Classification and natural history of clinically identifiable subtypes of cerebral infarction.
Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. Bamford J, et al. Lancet. 1991 Jun 22;337(8756):1521-6. doi: 10.1016/0140-6736(91)93206-o. Lancet. 1991. PMID: 1675378 Clinical Trial.
There were striking differences in natural history between the groups. The TACI group had a negligible chance of good functional outcome and mortality was high. More than twice as many deaths were due to the complications of immobility than to direct neurological sequelae …
There were striking differences in natural history between the groups. The TACI group had a negligible chance of good functional outc …
Ankle Injuries in Dancers.
Vosseller JT, Dennis ER, Bronner S. Vosseller JT, et al. J Am Acad Orthop Surg. 2019 Aug 15;27(16):582-589. doi: 10.5435/JAAOS-D-18-00596. J Am Acad Orthop Surg. 2019. PMID: 30789380 Review.
In many cases, a team approach to treatment with knowledgeable physical therapists can obviate the need for surgical treatment. If surgical treatment proves necessary, good results can be achieved with sound surgical technique and a well thought-out rehabilitation program. …
In many cases, a team approach to treatment with knowledgeable physical therapists can obviate the need for surgical treatment. If surgical …
Measuring acute postoperative pain using the visual analog scale: the minimal clinically important difference and patient acceptable symptom state.
Myles PS, Myles DB, Galagher W, Boyd D, Chew C, MacDonald N, Dennis A. Myles PS, et al. Br J Anaesth. 2017 Mar 1;118(3):424-429. doi: 10.1093/bja/aew466. Br J Anaesth. 2017. PMID: 28186223 Free article.
The patient acceptable symptom state (PASS) was defined as the 25th centile of the VAS corresponding to a positive patient response to having made a good recovery from surgery. RESULTS: We enrolled 224 patients at the first postoperative visit, and 219 of these were availa …
The patient acceptable symptom state (PASS) was defined as the 25th centile of the VAS corresponding to a positive patient response to havin …
Pediatric and Adolescent Shoulder Instability.
Kay J, Heyworth BE, Milewski MD, Kramer DE. Kay J, et al. Curr Rev Musculoskelet Med. 2023 Jul;16(7):263-273. doi: 10.1007/s12178-023-09837-z. Epub 2023 Apr 17. Curr Rev Musculoskelet Med. 2023. PMID: 37067690 Free PMC article. Review.
Although most pediatric and adolescent patients with MDI do well following non-surgical management alone, those that fail conservative management have good outcomes following arthroscopic or open capsulorrhaphy....
Although most pediatric and adolescent patients with MDI do well following non-surgical management alone, those that fail conservative manag …
Tuberculosis Drug Discovery: Challenges and New Horizons.
Fernandes GFS, Thompson AM, Castagnolo D, Denny WA, Dos Santos JL. Fernandes GFS, et al. J Med Chem. 2022 Jun 9;65(11):7489-7531. doi: 10.1021/acs.jmedchem.2c00227. Epub 2022 May 25. J Med Chem. 2022. PMID: 35612311 Review.
In this Perspective, we critically review those anti-TB compounds published in the last 6 years that demonstrate good in vivo efficacy against Mycobacterium tuberculosis. Additionally, we highlight the main challenges and strategies for developing new TB drugs and the curr …
In this Perspective, we critically review those anti-TB compounds published in the last 6 years that demonstrate good in vivo efficac …
Perspective: Neuroregenerative Nutrition.
Steindler DA, Reynolds BA. Steindler DA, et al. Adv Nutr. 2017 Jul 14;8(4):546-557. doi: 10.3945/an.117.015388. Print 2017 Jul. Adv Nutr. 2017. PMID: 28710142 Free PMC article.
Good health while aging depends upon optimal cellular and organ functioning that contribute to the regenerative ability of the body during the lifespan, especially when injuries and diseases occur. ...
Good health while aging depends upon optimal cellular and organ functioning that contribute to the regenerative ability of the body d …
Moving towards personalized medicine in rheumatoid arthritis.
de Jong TD, Vosslamber S, Verweij CL. de Jong TD, et al. Arthritis Res Ther. 2014;16(3):110. doi: 10.1186/ar4565. Arthritis Res Ther. 2014. PMID: 25166016 Free PMC article.
A crucial step in this approach is to discover subgroups of patients that are characterized by a good or poor treatment outcome. Dennis and colleagues have identified distinct pretreatment gene expression profiles in affected synovial tissue specimens and a tissue t …
A crucial step in this approach is to discover subgroups of patients that are characterized by a good or poor treatment outcome. D …
Chlorhexidine Bathing Effects on Health-Care-Associated Infections.
Denny J, Munro CL. Denny J, et al. Biol Res Nurs. 2017 Mar;19(2):123-136. doi: 10.1177/1099800416654013. Epub 2016 Jul 26. Biol Res Nurs. 2017. PMID: 27306279 Review.
Additional studies were identified by searching references used in original studies or review articles on this topic. PRINCIPLE FINDINGS: There is good evidence to support incorporating a CHG bathing regimen to reduce the incidence of CLABSIs, SSIs, vancomycin-resistant en …
Additional studies were identified by searching references used in original studies or review articles on this topic. PRINCIPLE FINDINGS: Th …
581 results