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Treponema pallidum, the stealth pathogen, changes, but how?
Radolf JD, Desrosiers DC. Radolf JD, et al. Among authors: desrosiers dc. Mol Microbiol. 2009 Jun;72(5):1081-6. doi: 10.1111/j.1365-2958.2009.06711.x. Epub 2009 May 4. Mol Microbiol. 2009. PMID: 19432802 Free PMC article.
The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host.
Eggers CH, Caimano MJ, Malizia RA, Kariu T, Cusack B, Desrosiers DC, Hazlett KR, Claiborne A, Pal U, Radolf JD. Eggers CH, et al. Among authors: desrosiers dc. Mol Microbiol. 2011 Nov;82(3):679-97. doi: 10.1111/j.1365-2958.2011.07845.x. Epub 2011 Oct 12. Mol Microbiol. 2011. PMID: 21923763 Free PMC article.
The transition from closed to open conformation of Treponema pallidum outer membrane-associated lipoprotein TP0453 involves membrane sensing and integration by two amphipathic helices.
Luthra A, Zhu G, Desrosiers DC, Eggers CH, Mulay V, Anand A, McArthur FA, Romano FB, Caimano MJ, Heuck AP, Malkowski MG, Radolf JD. Luthra A, et al. Among authors: desrosiers dc. J Biol Chem. 2011 Dec 2;286(48):41656-41668. doi: 10.1074/jbc.M111.305284. Epub 2011 Sep 29. J Biol Chem. 2011. PMID: 21965687 Free PMC article.
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