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Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aβ) in murine models of Alzheimer's disease (AD).
Rammes G, Mattusch C, Wulff M, Seeser F, Kreuzer M, Zhu K, Deussing JM, Herms J, Parsons CG. Rammes G, et al. Among authors: deussing jm. Neuropharmacology. 2017 Sep 1;123:100-115. doi: 10.1016/j.neuropharm.2017.02.003. Epub 2017 Feb 4. Neuropharmacology. 2017. PMID: 28174113
Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.
Rammes G, Hasenjäger A, Sroka-Saidi K, Deussing JM, Parsons CG. Rammes G, et al. Among authors: deussing jm. Neuropharmacology. 2011 May;60(6):982-90. doi: 10.1016/j.neuropharm.2011.01.051. Epub 2011 Feb 12. Neuropharmacology. 2011. PMID: 21310164
Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits.
Wang XD, Rammes G, Kraev I, Wolf M, Liebl C, Scharf SH, Rice CJ, Wurst W, Holsboer F, Deussing JM, Baram TZ, Stewart MG, Müller MB, Schmidt MV. Wang XD, et al. Among authors: deussing jm. J Neurosci. 2011 Sep 21;31(38):13625-34. doi: 10.1523/JNEUROSCI.2259-11.2011. J Neurosci. 2011. PMID: 21940453 Free PMC article.
Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.
Kratzer S, Mattusch C, Metzger MW, Dedic N, Noll-Hussong M, Kafitz KW, Eder M, Deussing JM, Holsboer F, Kochs E, Rammes G. Kratzer S, et al. Among authors: deussing jm. Front Cell Neurosci. 2013 Jul 19;7:91. doi: 10.3389/fncel.2013.00091. eCollection 2013. Front Cell Neurosci. 2013. PMID: 23882180 Free PMC article.
Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.
Dedic N, Pöhlmann ML, Richter JS, Mehta D, Czamara D, Metzger MW, Dine J, Bedenk BT, Hartmann J, Wagner KV, Jurik A, Almli LM, Lori A, Moosmang S, Hofmann F, Wotjak CT, Rammes G, Eder M, Chen A, Ressler KJ, Wurst W, Schmidt MV, Binder EB, Deussing JM. Dedic N, et al. Among authors: deussing jm. Mol Psychiatry. 2018 Mar;23(3):533-543. doi: 10.1038/mp.2017.133. Epub 2017 Jul 11. Mol Psychiatry. 2018. PMID: 28696432 Free PMC article.
Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice.
Stepan J, Heinz DE, Dethloff F, Wiechmann S, Martinelli S, Hafner K, Ebert T, Junglas E, Häusl AS, Pöhlmann ML, Jakovcevski M, Pape JC, Zannas AS, Bajaj T, Hermann A, Ma X, Pavenstädt H, Schmidt MV, Philipsen A, Turck CW, Deussing JM, Rammes G, Robinson AC, Payton A, Wehr MC, Stein V, Murgatroyd C, Kremerskothen J, Kuster B, Wotjak CT, Gassen NC. Stepan J, et al. Among authors: deussing jm. Sci Signal. 2024 Apr 30;17(834):eadj6603. doi: 10.1126/scisignal.adj6603. Epub 2024 Apr 30. Sci Signal. 2024. PMID: 38687825
Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus.
Schmidt MV, Trümbach D, Weber P, Wagner K, Scharf SH, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing JM, Wurst W, Binder EB, Holsboer F, Müller MB. Schmidt MV, et al. Among authors: deussing jm. J Neurosci. 2010 Dec 15;30(50):16949-58. doi: 10.1523/JNEUROSCI.4668-10.2010. J Neurosci. 2010. PMID: 21159965 Free PMC article.
163 results