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Challenges and barriers to optimising sedation in intensive care: a qualitative study in eight Scottish intensive care units.
Kydonaki K, Hanley J, Huby G, Antonelli J, Walsh TS; Development and Evaluation of Strategies to Improve Sedation practice in inTensive care (DESIST) study investigators. Kydonaki K, et al. BMJ Open. 2019 May 24;9(5):e024549. doi: 10.1136/bmjopen-2018-024549. BMJ Open. 2019. PMID: 31129576 Free PMC article.
OBJECTIVES: Various strategies to promote light sedation are highly recommended in recent guidelines, as deep sedation is associated with suboptimum patient outcomes. ...Recognition of the various challenges when mandating less sedation needs to be considered and novel sed …
OBJECTIVES: Various strategies to promote light sedation are highly recommended in recent guidelines, as deep sedation is associated …
Staff education, regular sedation and analgesia quality feedback, and a sedation monitoring technology for improving sedation and analgesia quality for critically ill, mechanically ventilated patients: a cluster randomised trial.
Walsh TS, Kydonaki K, Antonelli J, Stephen J, Lee RJ, Everingham K, Hanley J, Phillips EC, Uutela K, Peltola P, Cole S, Quasim T, Ruddy J, McDougall M, Davidson A, Rutherford J, Richards J, Weir CJ; Development and Evaluation of Strategies to Improve Sedation Practice in Intensive Care (DESIST) study investigators. Walsh TS, et al. Lancet Respir Med. 2016 Oct;4(10):807-817. doi: 10.1016/S2213-2600(16)30178-3. Epub 2016 Jul 26. Lancet Respir Med. 2016. PMID: 27473760 Free article. Clinical Trial.
Analysis used multilevel generalised linear mixed modelling to explore intervention effects in a single model taking clustering and patient-level factors into account. A concurrent mixed-methods process evaluation was undertaken to help understand the trial findings. The t …
Analysis used multilevel generalised linear mixed modelling to explore intervention effects in a single model taking clustering and patient- …