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Wildtype Kras2 can inhibit lung carcinogenesis in mice.
Zhang Z, Wang Y, Vikis HG, Johnson L, Liu G, Li J, Anderson MW, Sills RC, Hong HL, Devereux TR, Jacks T, Guan KL, You M. Zhang Z, et al. Among authors: devereux tr. Nat Genet. 2001 Sep;29(1):25-33. doi: 10.1038/ng721. Nat Genet. 2001. PMID: 11528387
High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene.
Sills RC, Hong HL, Melnick RL, Boorman GA, Devereux TR. Sills RC, et al. Among authors: devereux tr. Carcinogenesis. 1999 Apr;20(4):657-62. doi: 10.1093/carcin/20.4.657. Carcinogenesis. 1999. PMID: 10223196
108 results