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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2010 4
2011 2
2012 1
2013 2
2014 1
2016 2
2017 3
2018 3
2019 2
2020 2
2021 5
2022 5
2023 3
2024 3

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33 results

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Page 1
Endothelial DGKG promotes tumor angiogenesis and immune evasion in hepatocellular carcinoma.
Zhang L, Xu J, Zhou S, Yao F, Zhang R, You W, Dai J, Yu K, Zhang Y, Baheti T, Pu L, Xu J, Qian X, Zhang C, Xia Y, Dai X, Li Q, Wang X. Zhang L, et al. J Hepatol. 2024 Jan;80(1):82-98. doi: 10.1016/j.jhep.2023.10.006. Epub 2023 Oct 12. J Hepatol. 2024. PMID: 37838036
Importantly, targeting endothelial DGKG potentiated the efficiency of dual blockade of PD-1 and VEGFR-2. CONCLUSION: Hypoxia-induced EC-specific DGKG hyper-expression promotes tumor angiogenesis and immune evasion via the ZEB2/TGF-beta1 axis, suggesting EC-specific …
Importantly, targeting endothelial DGKG potentiated the efficiency of dual blockade of PD-1 and VEGFR-2. CONCLUSION: Hypoxia-induced …
A missense variant in DGKG as a recessive functional variant for hepatic fibrinogen storage disease in Wagyu cattle.
Jacinto JGP, Wohlsein P, Häfliger IM, Karl M, Pohlers M, Plobner L, Grünberg W, Drögemüller C. Jacinto JGP, et al. J Vet Intern Med. 2023 Nov-Dec;37(6):2631-2637. doi: 10.1111/jvim.16865. Epub 2023 Sep 8. J Vet Intern Med. 2023. PMID: 37681469 Free PMC article.
A trio whole-genome sequencing approach identified a deleterious homozygous missense variant in DGKG (p.Thr721Ile). The allele frequency in 209 genotyped Wagyu was 7.2%. This is a report of a DGKG-related recessive inherited disorder in cattle and adds DGKG t …
A trio whole-genome sequencing approach identified a deleterious homozygous missense variant in DGKG (p.Thr721Ile). The allele freque …
Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation.
Liu YQ, Ling TW, Wang HY, Yang YH, Song WJ, Wang TC. Liu YQ, et al. Stem Cell Res. 2022 May;61:102768. doi: 10.1016/j.scr.2022.102768. Epub 2022 Mar 28. Stem Cell Res. 2022. PMID: 35421845 Free article.
Base on the non-integrating episomal vector technique, a human induced pluripotent stem cell (iPSC) line, termed as LZUSHI001-A, was generated from peripheral blood mononuclear cells (PBMCs) of a 11-year-old male patient with Epilepsy, who had a heterozygous (c.2042G>A, p.R681 …
Base on the non-integrating episomal vector technique, a human induced pluripotent stem cell (iPSC) line, termed as LZUSHI001-A, was generat …
Role of Diacylglycerol Kinases in Acute Myeloid Leukemia.
Gravina T, Boggio CMT, Gorla E, Racca L, Polidoro S, Centonze S, Ferrante D, Lunghi M, Graziani A, Corà D, Baldanzi G. Gravina T, et al. Biomedicines. 2023 Jul 1;11(7):1877. doi: 10.3390/biomedicines11071877. Biomedicines. 2023. PMID: 37509516 Free PMC article.
According to cancer expression databases, acute myeloid leukemia (AML) exhibits significant overexpression of multiple DGK isoforms, including DGKA, DGKD and DGKG, without a precise correlation with specific AML subtypes. In the TGCA database, high DGKA expression negative …
According to cancer expression databases, acute myeloid leukemia (AML) exhibits significant overexpression of multiple DGK isoforms, includi …
Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.
Kai M, Yamamoto E, Sato A, Yamano HO, Niinuma T, Kitajima H, Harada T, Aoki H, Maruyama R, Toyota M, Hatahira T, Nakase H, Sugai T, Yamashita T, Toyota M, Suzuki H. Kai M, et al. Mol Carcinog. 2017 Jul;56(7):1743-1752. doi: 10.1002/mc.22631. Epub 2017 Mar 6. Mol Carcinog. 2017. PMID: 28218473
DGKG methylation was frequently observed in primary CRCs (73/141, 51.8%) and was positively associated with KRAS and BRAF mutations and with the CpG island methylator phenotype (CIMP). DGKG methylation was also frequently detected in colorectal adenomas (89 of 177, …
DGKG methylation was frequently observed in primary CRCs (73/141, 51.8%) and was positively associated with KRAS and BRAF mutations a …
Identification of genes regulating GABAergic interneuron maturation.
Fukumoto K, Tamada K, Toya T, Nishino T, Yanagawa Y, Takumi T. Fukumoto K, et al. Neurosci Res. 2018 Sep;134:18-29. doi: 10.1016/j.neures.2017.11.010. Epub 2017 Dec 2. Neurosci Res. 2018. PMID: 29203264
Correlational analysis revealed that Dgkg is dominantly expressed in somatostatin (SST)-expressing GABAergic interneurons. The functional study of Dgkg using GE neurons indicated alteration in neurite outgrowth of GABAergic neurons. ...
Correlational analysis revealed that Dgkg is dominantly expressed in somatostatin (SST)-expressing GABAergic interneurons. The functi …
Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese.
Ng MC, Tam CH, So WY, Ho JS, Chan AW, Lee HM, Wang Y, Lam VK, Chan JC, Ma RC. Ng MC, et al. J Clin Endocrinol Metab. 2010 May;95(5):2418-25. doi: 10.1210/jc.2009-2077. Epub 2010 Mar 9. J Clin Endocrinol Metab. 2010. PMID: 20215397
RESEARCH DESIGN AND METHODS: We examined 14 associated single-nucleotide polymorphisms at 12 loci (NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15) in 605 healthy adults, 1087 healthy adolescents and 6013 T2D patient …
RESEARCH DESIGN AND METHODS: We examined 14 associated single-nucleotide polymorphisms at 12 loci (NEGR1, SEC16B, TMEM18, ETV5/DGKG, …
De novo DNA methylation induced by circulating extracellular vesicles from acute coronary syndrome patients.
Schiano C, Balbi C, Burrello J, Ruocco A, Infante T, Fiorito C, Panella S, Barile L, Mauro C, Vassalli G, Napoli C. Schiano C, et al. Atherosclerosis. 2022 Aug;354:41-52. doi: 10.1016/j.atherosclerosis.2022.06.1026. Epub 2022 Jul 6. Atherosclerosis. 2022. PMID: 35830762
In the most enriched subnetwork, the hub gene SRC was connected to NOTCH1, FOXO3, CDC42, IKBKG, RXRA, DGKG, BAIAP2 genes that were showed to have many molecular effects on various cell types into onset of several CVDs. Modulation in gene expression after ACS-EVs treatment …
In the most enriched subnetwork, the hub gene SRC was connected to NOTCH1, FOXO3, CDC42, IKBKG, RXRA, DGKG, BAIAP2 genes that were sh …
Comprehensive analysis reveals a 5-gene signature and immune cell infiltration in Alzheimer's disease with qPCR validation.
Jin F, Xi Y, Xie D, Wang Q. Jin F, et al. Front Genet. 2022 Aug 25;13:913535. doi: 10.3389/fgene.2022.913535. eCollection 2022. Front Genet. 2022. PMID: 36092935 Free PMC article.
Second, combining the LASSO logistic regression and SVM-RFE, we obtained five biomarkers (DGKG, MAP3K7IP2, NFKBIE, VIP, and PCCB), which may reveal the key pathogenetic features of AD and serve as diagnostic markers assessed by the ROC curve (AUC = 0.9716) and validation o …
Second, combining the LASSO logistic regression and SVM-RFE, we obtained five biomarkers (DGKG, MAP3K7IP2, NFKBIE, VIP, and PCCB), wh …
Sex Disparities of Genomic Determinants in Response to Immune Checkpoint Inhibitors in Melanoma.
Shi F, Zhang W, Yang Y, Yang Y, Zhao J, Xie M, Sheng C, Wang S, Wang Q. Shi F, et al. Front Immunol. 2021 Nov 2;12:721409. doi: 10.3389/fimmu.2021.721409. eCollection 2021. Front Immunol. 2021. PMID: 34795662 Free PMC article.
RESULTS: Of the 15 SMGs identified in this study, three genes (i.e., CFH, DGKG, and PPP6C) were found to exhibit sex differences with respect to ICI efficacy. ...
RESULTS: Of the 15 SMGs identified in this study, three genes (i.e., CFH, DGKG, and PPP6C) were found to exhibit sex differences with …
33 results