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Cooperativity of c-MYC with Krüppel-Like Factor 6 Splice Variant 1 induces phenotypic plasticity and promotes prostate cancer progression and metastasis.
Izadmehr S, Fernandez-Hernandez H, Wiredja D, Kirschenbaum A, Lee-Poturalski C, Tavassoli P, Yao S, Schlatzer D, Hoon D, Difeo A, Levine AC, Mosquera JM, Galsky MD, Cordon-Cardo C, Narla G. Izadmehr S, et al. Among authors: difeo a. bioRxiv [Preprint]. 2024 Feb 1:2024.01.30.577982. doi: 10.1101/2024.01.30.577982. bioRxiv. 2024. PMID: 38352401 Free PMC article. Preprint.
The nutritional supplement taurine activates p53-dependent and independent tumor suppressor mechanisms in various cellular models of ovarian cancer.
Centeno D, Farsinejad S, Kochetkova E, Volpari T, Klupczynska-Gabryszak A, Kung D, Polotaye T, Hyde E, Greenberg M, Pavlovic T, Alshehri S, Sullivan W, Plewa S, Vakifahmetoglu-Norberg H, Monsma FJ, Muller PAJ, Matysiak J, Zaborowski M, DiFeo A, Andres-Martin L, Norberg E, Iwanicki M. Centeno D, et al. Among authors: difeo a. bioRxiv [Preprint]. 2023 Aug 26:2023.02.24.529893. doi: 10.1101/2023.02.24.529893. bioRxiv. 2023. PMID: 36909636 Free PMC article. Preprint.
Small-Molecule-Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death.
Avelar RA, Armstrong AJ, Carvette G, Gupta R, Puleo N, Colina JA, Joseph P, Sobeck AM, O'Connor CM, Raines B, Gandhi A, Dziubinski ML, Ma DS, Resnick K, Singh S, Zanotti K, Nagel C, Waggoner S, Thomas DG, Skala SL, Zhang J, Narla G, DiFeo A. Avelar RA, et al. Among authors: difeo a. Mol Cancer Ther. 2023 May 4;22(5):599-615. doi: 10.1158/1535-7163.MCT-21-0880. Mol Cancer Ther. 2023. PMID: 36788429 Free PMC article.
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.
Achreja A, Yu T, Mittal A, Choppara S, Animasahun O, Nenwani M, Wuchu F, Meurs N, Mohan A, Jeon JH, Sarangi I, Jayaraman A, Owen S, Kulkarni R, Cusato M, Weinberg F, Kweon HK, Subramanian C, Wicha MS, Merajver SD, Nagrath S, Cho KR, DiFeo A, Lu X, Nagrath D. Achreja A, et al. Among authors: difeo a. Nat Metab. 2022 Sep;4(9):1119-1137. doi: 10.1038/s42255-022-00636-3. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131208
76 results