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The dichloromethane extract of the ethnomedicinal plant Neurolaena lobata inhibits NPM/ALK expression which is causal for anaplastic large cell lymphomagenesis.
Unger C, Popescu R, Giessrigl B, Laimer D, Heider S, Seelinger M, Diaz R, Wallnöfer B, Egger G, Hassler M, Knöfler M, Saleh L, Sahin E, Grusch M, Fritzer-Szekeres M, Dolznig H, Frisch R, Kenner L, Kopp B, Krupitza G. Unger C, et al. Among authors: diaz r. Int J Oncol. 2013 Jan;42(1):338-48. doi: 10.3892/ijo.2012.1690. Epub 2012 Nov 6. Int J Oncol. 2013. PMID: 23135783
In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum.
Gridling M, Stark N, Madlener S, Lackner A, Popescu R, Benedek B, Diaz R, Tut FM, Nha Vo TP, Huber D, Gollinger M, Saiko P, Ozmen A, Mosgoeller W, De Martin R, Eytner R, Wagner KH, Grusch M, Fritzer-Szekeres M, Szekeres T, Kopp B, Frisch R, Krupitza G. Gridling M, et al. Among authors: diaz r. Int J Oncol. 2009 Apr;34(4):1117-28. doi: 10.3892/ijo_00000239. Int J Oncol. 2009. PMID: 19287970
Separation of anti-neoplastic activities by fractionation of a Pluchea odorata extract.
Bauer S, Singhuber J, Seelinger M, Unger C, Viola K, Vonach C, Giessrigl B, Madlener S, Stark N, Wallnofer B, Wagner KH, Fritzer-Szekeres M, Szekeres T, Diaz R, Tut F, Frisch R, Feistel B, Kopp B, Krupitza G, Popescu R. Bauer S, et al. Among authors: diaz r. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1326-36. doi: 10.2741/e336. Front Biosci (Elite Ed). 2011. PMID: 21622139 Free article.
An apolar extract of Critonia morifolia inhibits c-Myc, cyclin D1, Cdc25A, Cdc25B, Cdc25C and Akt and induces apoptosis.
Unger C, Popescu R, Giessrigl B, Rarova L, Herbacek I, Seelinger M, Diaz R, Wallnöfer B, Fritzer-Szekeres M, Szekeres T, Frisch R, Doležal K, Strnad M, De Martin R, Grusch M, Kopp B, Krupitza G. Unger C, et al. Among authors: diaz r. Int J Oncol. 2012 Jun;40(6):2131-9. doi: 10.3892/ijo.2012.1412. Epub 2012 Mar 23. Int J Oncol. 2012. PMID: 22446629
Lobatin B inhibits NPM/ALK and NF-κB attenuating anaplastic-large-cell-lymphomagenesis and lymphendothelial tumour intravasation.
Kiss I, Unger C, Huu CN, Atanasov AG, Kramer N, Chatruphonprasert W, Brenner S, McKinnon R, Peschel A, Vasas A, Lajter I, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G. Kiss I, et al. Among authors: diaz r. Cancer Lett. 2015 Jan 28;356(2 Pt B):994-1006. doi: 10.1016/j.canlet.2014.11.019. Epub 2014 Nov 15. Cancer Lett. 2015. PMID: 25444930
The germacranolide sesquiterpene lactone neurolenin B of the medicinal plant Neurolaena lobata (L.) R.Br. ex Cass inhibits NPM/ALK-driven cell expansion and NF-κB-driven tumour intravasation.
Unger C, Kiss I, Vasas A, Lajter I, Kramer N, Atanasov AG, Nguyen CH, Chatuphonprasert W, Brenner S, Krieger S, McKinnon R, Peschel A, Kain R, Saiko P, Szekeres T, Kenner L, Hassler MR, Diaz R, Frisch R, Dirsch VM, Jäger W, de Martin R, Bochkov VN, Passreiter CM, Peter-Vörösmarty B, Mader RM, Grusch M, Dolznig H, Kopp B, Zupko I, Hohmann J, Krupitza G. Unger C, et al. Among authors: diaz r. Phytomedicine. 2015 Aug 15;22(9):862-74. doi: 10.1016/j.phymed.2015.06.003. Epub 2015 Jun 26. Phytomedicine. 2015. PMID: 26220634
Pharmacological insight into the anti-inflammatory activity of sesquiterpene lactones from Neurolaena lobata (L.) R.Br. ex Cass.
McKinnon R, Binder M, Zupkó I, Afonyushkin T, Lajter I, Vasas A, de Martin R, Unger C, Dolznig H, Diaz R, Frisch R, Passreiter CM, Krupitza G, Hohmann J, Kopp B, Bochkov VN. McKinnon R, et al. Among authors: diaz r. Phytomedicine. 2014 Oct 15;21(12):1695-701. doi: 10.1016/j.phymed.2014.07.019. Epub 2014 Sep 15. Phytomedicine. 2014. PMID: 25442279
Fractionation of an Extract of Pluchea odorata Separates a Property Indicative for the Induction of Cell Plasticity from One That Inhibits a Neoplastic Phenotype.
Seelinger M, Popescu R, Seephonkai P, Singhuber J, Giessrigl B, Unger C, Bauer S, Wagner KH, Fritzer-Szekeres M, Szekeres T, Diaz R, Tut FM, Frisch R, Feistel B, Kopp B, Krupitza G. Seelinger M, et al. Among authors: diaz r. Evid Based Complement Alternat Med. 2012;2012:701927. doi: 10.1155/2012/701927. Epub 2012 Mar 13. Evid Based Complement Alternat Med. 2012. PMID: 22474515 Free PMC article.
2,293 results