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Biofabrication of synthetic human liver tissue with advanced programmable functions.
Florentino RM, Morita K, Haep N, Motomura T, Diaz-Aragon R, Faccioli LAP, Collin de l'Hortet A, Cetin Z, Frau C, Vernetti L, Amler AK, Thomas A, Lam T, Kloke L, Takeishi K, Taylor DL, Fox IJ, Soto-Gutierrez A. Florentino RM, et al. Among authors: diaz aragon r. iScience. 2022 Nov 4;25(12):105503. doi: 10.1016/j.isci.2022.105503. eCollection 2022 Dec 22. iScience. 2022. PMID: 36404924 Free PMC article.
Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver-Enriched Transcription Factors and Functional Proteins in End-Stage Cirrhotic Human Hepatocytes.
Tafaleng EN, Mukherjee A, Bell A, Morita K, Guzman-Lepe J, Haep N, Florentino RM, Diaz-Aragon R, Frau C, Ostrowska A, Schultz JR, Martini PGV, Soto-Gutierrez A, Fox IJ. Tafaleng EN, et al. Among authors: diaz aragon r. Hepatol Commun. 2021 Nov;5(11):1911-1926. doi: 10.1002/hep4.1763. Epub 2021 Jul 1. Hepatol Commun. 2021. PMID: 34558820 Free PMC article.
Therapeutic Potential of HNF4α in End-stage Liver Disease.
Diaz-Aragon R, Coard MC, Amirneni S, Faccioli L, Haep N, Malizio MR, Motomura T, Kocas-Kilicarslan ZN, Ostrowska A, Florentino RM, Frau C. Diaz-Aragon R, et al. Organogenesis. 2021 Oct 2;17(3-4):126-135. doi: 10.1080/15476278.2021.1994273. Organogenesis. 2021. PMID: 35114889 Free PMC article. Review.
Transmembrane channel activity in human hepatocytes and cholangiocytes derived from induced pluripotent stem cells.
Florentino RM, Li Q, Coard MC, Haep N, Motomura T, Diaz-Aragon R, Faccioli LAP, Amirneni S, Kocas-Kilicarslan ZN, Ostrowska A, Squires JE, Feranchak AP, Soto-Gutierrez A. Florentino RM, et al. Among authors: diaz aragon r. Hepatol Commun. 2022 Jul;6(7):1561-1573. doi: 10.1002/hep4.1920. Epub 2022 Mar 15. Hepatol Commun. 2022. PMID: 35289126 Free PMC article.
From a Single Cell to a Whole Human Liver: Disease Modeling and Transplantation.
Motomura T, Faccioli LAP, Diaz-Aragon R, Kocas-Kilicarslan ZN, Haep N, Florentino RM, Amirneni S, Cetin Z, Peri BS, Morita K, Ostrowska A, Takeishi K, Soto-Gutierrez A, Tafaleng EN. Motomura T, et al. Among authors: diaz aragon r. Semin Liver Dis. 2022 Nov;42(4):413-422. doi: 10.1055/a-1934-5404. Epub 2022 Aug 31. Semin Liver Dis. 2022. PMID: 36044927 Free PMC article.
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, Bawa PS, So J, Florentino RM, Wu S, Sarjoo A, Truong E, Smith AR, Wang F, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V. Rizvi F, et al. Among authors: diaz aragon r. Cell Stem Cell. 2023 Dec 7;30(12):1640-1657.e8. doi: 10.1016/j.stem.2023.10.008. Epub 2023 Nov 28. Cell Stem Cell. 2023. PMID: 38029740 Free article.
Polymorphisms Associated With Metabolic Dysfunction-Associated Steatotic Liver Disease Influence the Progression of End-Stage Liver Disease.
Kocas-Kilicarslan ZN, Cetin Z, Faccioli LAP, Motomura T, Amirneni S, Diaz-Aragon R, Florentino RM, Sun Y, Pla-Palacin I, Xia M, Miedel MT, Kurihara T, Hu Z, Ostrowska A, Wang Z, Constantine R, Li A, Taylor DL, Behari J, Soto-Gutierrez A, Tafaleng EN. Kocas-Kilicarslan ZN, et al. Among authors: diaz aragon r. Gastro Hep Adv. 2024;3(1):67-77. doi: 10.1016/j.gastha.2023.09.011. Epub 2023 Oct 5. Gastro Hep Adv. 2024. PMID: 38292457 Free PMC article.
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, So J, Florentino RM, Smith AR, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V. Rizvi F, et al. Among authors: diaz aragon r. bioRxiv [Preprint]. 2023 Apr 18:2023.04.17.537186. doi: 10.1101/2023.04.17.537186. bioRxiv. 2023. PMID: 37131823 Free PMC article. Updated. Preprint.
15 results