Ding X - Search Results

1

Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: effects on development, reproduction, and microsomal cytochrome P450.

Wu L, Gu J, Cui H, Zhang QY, Behr M, Fang C, Weng Y, Kluetzman K, Swiatek PJ, Yang W, Kaminsky L, Ding X. Wu L, et al. Among authors: ding x. J Pharmacol Exp Ther. 2005 Jan;312(1):35-43. doi: 10.1124/jpet.104.073353. Epub 2004 Aug 24. J Pharmacol Exp Ther. 2005. PMID: 15328377

2

Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant.

Zhang X, Su T, Zhang QY, Gu J, Caggana M, Li H, Ding X. Zhang X, et al. Among authors: ding x. J Pharmacol Exp Ther. 2002 Aug;302(2):416-23. doi: 10.1124/jpet.302.2.416. J Pharmacol Exp Ther. 2002. PMID: 12130698

3

Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase.

Gu J, Weng Y, Zhang QY, Cui H, Behr M, Wu L, Yang W, Zhang L, Ding X. Gu J, et al. Among authors: ding x. J Biol Chem. 2003 Jul 11;278(28):25895-901. doi: 10.1074/jbc.M303125200. Epub 2003 Apr 15. J Biol Chem. 2003. PMID: 12697746 Free article.

4

Conditional knockout of the mouse NADPH-cytochrome p450 reductase gene.

Wu L, Gu J, Weng Y, Kluetzman K, Swiatek P, Behr M, Zhang QY, Zhuo X, Xie Q, Ding X. Wu L, et al. Among authors: ding x. Genesis. 2003 Aug;36(4):177-81. doi: 10.1002/gene.10214. Genesis. 2003. PMID: 12929087

5

Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression.

Zhuo X, Gu J, Behr MJ, Swiatek PJ, Cui H, Zhang QY, Xie Y, Collins DN, Ding X. Zhuo X, et al. Among authors: ding x. J Pharmacol Exp Ther. 2004 Feb;308(2):719-28. doi: 10.1124/jpet.103.060301. Epub 2003 Nov 10. J Pharmacol Exp Ther. 2004. PMID: 14610229

6

In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa.

Gu J, Cui H, Behr M, Zhang L, Zhang QY, Yang W, Hinson JA, Ding X. Gu J, et al. Among authors: ding x. Mol Pharmacol. 2005 Mar;67(3):623-30. doi: 10.1124/mol.104.007898. Epub 2004 Nov 18. Mol Pharmacol. 2005. PMID: 15550675

7

Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.

Weng Y, DiRusso CC, Reilly AA, Black PN, Ding X. Weng Y, et al. Among authors: ding x. J Biol Chem. 2005 Sep 9;280(36):31686-98. doi: 10.1074/jbc.M504447200. Epub 2005 Jul 8. J Biol Chem. 2005. PMID: 16006652 Free article.

8

A mouse model with liver-specific deletion and global suppression of the NADPH-cytochrome P450 reductase gene: characterization and utility for in vivo studies of cyclophosphamide disposition.

Gu J, Chen CS, Wei Y, Fang C, Xie F, Kannan K, Yang W, Waxman DJ, Ding X. Gu J, et al. Among authors: ding x. J Pharmacol Exp Ther. 2007 Apr;321(1):9-17. doi: 10.1124/jpet.106.118240. Epub 2007 Jan 11. J Pharmacol Exp Ther. 2007. PMID: 17218484

9

Role of small intestinal cytochromes p450 in the bioavailability of oral nifedipine.

Zhang QY, Kaminsky LS, Dunbar D, Zhang J, Ding X. Zhang QY, et al. Among authors: ding x. Drug Metab Dispos. 2007 Sep;35(9):1617-23. doi: 10.1124/dmd.107.016543. Epub 2007 Jun 13. Drug Metab Dispos. 2007. PMID: 17567730

10

Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.

Weng Y, Fang C, Turesky RJ, Behr M, Kaminsky LS, Ding X. Weng Y, et al. Among authors: ding x. Cancer Res. 2007 Aug 15;67(16):7825-32. doi: 10.1158/0008-5472.CAN-07-1006. Cancer Res. 2007. PMID: 17699788

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