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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 1
2003 2
2004 1
2005 2
2006 6
2007 3
2008 3
2009 2
2010 2
2011 5
2012 5
2013 7
2014 6
2015 6
2016 4
2017 6
2018 14
2019 16
2020 20
2021 34
2022 35
2023 26
2024 11

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197 results

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DLGAP5 promotes gallbladder cancer migration and tumor-associated macrophage M2 polarization by activating cAMP.
Huang J, Zheng M, Li Y, Xu D, Tian D. Huang J, et al. Cancer Immunol Immunother. 2023 Oct;72(10):3203-3216. doi: 10.1007/s00262-023-03484-6. Epub 2023 Jul 8. Cancer Immunol Immunother. 2023. PMID: 37421434 Free PMC article.
GST-pulldown showed the direct interact between DLGAP5 and cAMP. Macrophage polarization assay was further conducted to detect the effects of DLGAP5 on macrophage M2 polarization. ...In vivo, GBC-SD with DLGAP5 knockdown was subcutaneously injected into nude …
GST-pulldown showed the direct interact between DLGAP5 and cAMP. Macrophage polarization assay was further conducted to detect the ef …
DLGAP5 triggers proliferation and metastasis of bladder cancer by stabilizing E2F1 via USP11.
Zhou F, Deng Z, Shen D, Lu M, Li M, Yu J, Xiao Y, Wang G, Qian K, Ju L, Wang X. Zhou F, et al. Oncogene. 2024 Feb;43(8):594-607. doi: 10.1038/s41388-023-02932-y. Epub 2024 Jan 5. Oncogene. 2024. PMID: 38182895
Mechanistically, the findings demonstrated that DLGAP5 was a direct binding partner of E2F1 and that DLGAP5 stabilized E2F1 by preventing the ubiquitination of E2F1 through USP11. Furthermore, as a pivotal transcription factor, E2F1 fosters the transcription of D …
Mechanistically, the findings demonstrated that DLGAP5 was a direct binding partner of E2F1 and that DLGAP5 stabilized E2F1 by …
DLGAP5 promotes lung adenocarcinoma growth via upregulating PLK1 and serves as a therapeutic target.
Chen M, Zhang S, Wang F, He J, Jiang W, Zhang L. Chen M, et al. J Transl Med. 2024 Feb 27;22(1):209. doi: 10.1186/s12967-024-04910-8. J Transl Med. 2024. PMID: 38414025 Free PMC article.
Moreover, AT9283 significantly suppressed DLGAP5 and PLK1 expression, while DLGAP5 overexpression significantly reversed AT9283-induced PLK1 suppression. ...Targeting DLGAP5 by AT9283, our newly identified DLGAP5 inhibitor, suppresses LUAD growth. ...
Moreover, AT9283 significantly suppressed DLGAP5 and PLK1 expression, while DLGAP5 overexpression significantly reversed AT928 …
DLGAP5 Regulates the Proliferation, Migration, Invasion, and Cell Cycle of Breast Cancer Cells via the JAK2/STAT3 Signaling Axis.
Li Y, Wei J, Sun Y, Zhou W, Ma X, Guo J, Zhang H, Jin T. Li Y, et al. Int J Mol Sci. 2023 Oct 31;24(21):15819. doi: 10.3390/ijms242115819. Int J Mol Sci. 2023. PMID: 37958803 Free PMC article.
Moreover, DLGAP5 was highly expressed in BC. The down-regulation of DLGAP5 may inhibit the proliferation, migration, invasion, and cell cycle of BC cells, and the opposite was true for DLGAP5 overexpression. Correspondingly, silencing or overexpression of the …
Moreover, DLGAP5 was highly expressed in BC. The down-regulation of DLGAP5 may inhibit the proliferation, migration, invasion, …
DLGAP5 knockdown inactivates the Wnt/beta-catenin signal to repress endometrial cancer cell malignant activities.
Chen R, Liu J, Hu J, Li C, Liu Y, Pan W. Chen R, et al. Environ Toxicol. 2023 Mar;38(3):685-693. doi: 10.1002/tox.23720. Epub 2022 Dec 1. Environ Toxicol. 2023. PMID: 36454672
DLGAP5 was highly expressed and correlated with poor prognosis in EC patients. ...Additionally, DLGAP5 knockdown inactivated the Wnt/beta-catenin signaling pathway in EC cells. ...
DLGAP5 was highly expressed and correlated with poor prognosis in EC patients. ...Additionally, DLGAP5 knockdown inactivated t …
DLG7/DLGAP5 as a potential therapeutic target in gastric cancer.
Li K, Fu X, Wu P, Zhaxi B, Luo H, Li Q. Li K, et al. Chin Med J (Engl). 2022 Aug 8;135(13):1616-8. doi: 10.1097/CM9.0000000000001859. Online ahead of print. Chin Med J (Engl). 2022. PMID: 35075051 Free PMC article. No abstract available.
Knockdown of DLGAP5 suppresses cell proliferation, induces G(2)/M phase arrest and apoptosis in ovarian cancer.
Zhang H, Liu Y, Tang S, Qin X, Li L, Zhou J, Zhang J, Liu B. Zhang H, et al. Exp Ther Med. 2021 Nov;22(5):1245. doi: 10.3892/etm.2021.10680. Epub 2021 Sep 2. Exp Ther Med. 2021. PMID: 34539841 Free PMC article.
However, the prognostic value and biological function of DLGAP5 in ovarian cancer (OC) still remain unclear. The present study investigated the expression pattern of DLGAP5 by searching the Oncomine microarray database. ...Knockdown of DLGAP5 was achieved by …
However, the prognostic value and biological function of DLGAP5 in ovarian cancer (OC) still remain unclear. The present study invest …
Prognostic value of DLGAP5 in colorectal cancer.
Branchi V, García SA, Radhakrishnan P, Győrffy B, Hissa B, Schneider M, Reißfelder C, Schölch S. Branchi V, et al. Int J Colorectal Dis. 2019 Aug;34(8):1455-1465. doi: 10.1007/s00384-019-03339-6. Epub 2019 Jul 8. Int J Colorectal Dis. 2019. PMID: 31286215
In addition, DLGAP5 expression correlates with nodal status and advanced UICC stage (III-IV).Subgroup analyses revealed a correlation between DLGAP5 overexpression and poor survival in patients with non-metastatic disease (M0). ...CONCLUSIONS: The results of this st …
In addition, DLGAP5 expression correlates with nodal status and advanced UICC stage (III-IV).Subgroup analyses revealed a correlation …
Identification and prognostic value of DLGAP5 in endometrial cancer.
Zheng R, Shi Z, Li W, Yu J, Wang Y, Zhou Q. Zheng R, et al. PeerJ. 2020 Nov 27;8:e10433. doi: 10.7717/peerj.10433. eCollection 2020. PeerJ. 2020. PMID: 33312770 Free PMC article.
METHODOLOGY: Microarray datasets (GSE17025, GSE39099 and GSE63678) from the GEO database were used for comparative analysis, and their intersection was obtained by applying the Venn diagram, and DLGAP5 was selected as the target gene. Next, transcriptome data (n = 578) was …
METHODOLOGY: Microarray datasets (GSE17025, GSE39099 and GSE63678) from the GEO database were used for comparative analysis, and their inter …
High Expression of DLGAP5 Indicates Poor Prognosis and Immunotherapy in Lung Adenocarcinoma and Promotes Proliferation through Regulation of the Cell Cycle.
Tang X, Zhou H, Liu Y. Tang X, et al. Dis Markers. 2023 Jan 19;2023:9292536. doi: 10.1155/2023/9292536. eCollection 2023. Dis Markers. 2023. PMID: 36712920 Free PMC article.
The CCK-8 and colony formation assays were performed to assess the effect of DLGAP5 on cell proliferation. RNA sequencing (RNA-seq) and enrichment analyses were utilized to explore the biological functions of DLGAP5. ...LUAD patients with high DLGAP5 expressi …
The CCK-8 and colony formation assays were performed to assess the effect of DLGAP5 on cell proliferation. RNA sequencing (RNA-seq) a …
197 results