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LncRNA Dnmt3aos regulates Dnmt3a expression leading to aberrant DNA methylation in macrophage polarization.
FASEB J. 2020 Apr;34(4):5077-5091. doi: 10.1096/fj.201902379R. Epub 2020 Feb 13.
FASEB J. 2020.
PMID: 32052888
Functional experiments further confirmed that Dnmt3aos were highly expressed in M(IL-4) macrophages and participated in the regulation of Dnmt3a expression, and played a key role in macrophage polarization. The DNA methylation profiles between the Dnmt3aos knockdown …
Functional experiments further confirmed that Dnmt3aos were highly expressed in M(IL-4) macrophages and participated in the regulatio …
Exosome membrane-modified M2 macrophages targeted nanomedicine: Treatment for allergic asthma.
Pei W, Li X, Bi R, Zhang X, Zhong M, Yang H, Zhang Y, Lv K.
Pei W, et al.
J Control Release. 2021 Oct 10;338:253-267. doi: 10.1016/j.jconrel.2021.08.024. Epub 2021 Aug 19.
J Control Release. 2021.
PMID: 34418524
Free article.
The resulting exosome membrane coated PLGA@Dnmt3aos(smart silencer) (EM-PLGA@Dnmt3aos(smart silencer)) was administered intravenously into Der f1-induced asthma mice, which was followed by the investigation of therapeutic outcomes and the mechanism in vivo. RESULTS: …
The resulting exosome membrane coated PLGA@Dnmt3aos(smart silencer) (EM-PLGA@Dnmt3aos(smart silencer)) was administered intrav …
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