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Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells.
Lam PP, Ohno M, Dolai S, He Y, Qin T, Liang T, Zhu D, Kang Y, Liu Y, Kauppi M, Xie L, Wan WC, Bin NR, Sugita S, Olkkonen VM, Takahashi N, Kasai H, Gaisano HY. Lam PP, et al. Among authors: dolai s. Diabetes. 2013 Jul;62(7):2416-28. doi: 10.2337/db12-1380. Epub 2013 Feb 19. Diabetes. 2013. PMID: 23423569 Free PMC article.
Dual role of VAMP8 in regulating insulin exocytosis and islet β cell growth.
Zhu D, Zhang Y, Lam PP, Dolai S, Liu Y, Cai EP, Choi D, Schroer SA, Kang Y, Allister EM, Qin T, Wheeler MB, Wang CC, Hong WJ, Woo M, Gaisano HY. Zhu D, et al. Among authors: dolai s. Cell Metab. 2012 Aug 8;16(2):238-49. doi: 10.1016/j.cmet.2012.07.001. Epub 2012 Jul 26. Cell Metab. 2012. PMID: 22841572 Free article.
New Roles of Syntaxin-1A in Insulin Granule Exocytosis and Replenishment.
Liang T, Qin T, Xie L, Dolai S, Zhu D, Prentice KJ, Wheeler M, Kang Y, Osborne L, Gaisano HY. Liang T, et al. Among authors: dolai s. J Biol Chem. 2017 Feb 10;292(6):2203-2216. doi: 10.1074/jbc.M116.769885. Epub 2016 Dec 28. J Biol Chem. 2017. PMID: 28031464 Free PMC article.
Syntaxin 2 Acts as Inhibitory SNARE for Insulin Granule Exocytosis.
Zhu D, Xie L, Kang Y, Dolai S, Bondo Hansen J, Qin T, Xie H, Liang T, Rubin DC, Osborne L, Gaisano HY. Zhu D, et al. Among authors: dolai s. Diabetes. 2017 Apr;66(4):948-959. doi: 10.2337/db16-0636. Epub 2017 Jan 23. Diabetes. 2017. PMID: 28115395 Free PMC article.
Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis.
Qin T, Liang T, Zhu D, Kang Y, Xie L, Dolai S, Sugita S, Takahashi N, Ostenson CG, Banks K, Gaisano HY. Qin T, et al. Among authors: dolai s. EBioMedicine. 2017 Feb;16:262-274. doi: 10.1016/j.ebiom.2017.01.030. Epub 2017 Jan 22. EBioMedicine. 2017. PMID: 28163042 Free PMC article.
67 results