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The two variants of the Streptococcus pneumoniae pilus 1 RrgA adhesin retain the same function and elicit cross-protection in vivo.
Moschioni M, Emolo C, Biagini M, Maccari S, Pansegrau W, Donati C, Hilleringmann M, Ferlenghi I, Ruggiero P, Sinisi A, Pizza M, Norais N, Barocchi MA, Masignani V. Moschioni M, et al. Among authors: donati c. Infect Immun. 2010 Dec;78(12):5033-42. doi: 10.1128/IAI.00601-10. Epub 2010 Sep 7. Infect Immun. 2010. PMID: 20823200 Free PMC article.
Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related.
Moschioni M, Donati C, Muzzi A, Masignani V, Censini S, Hanage WP, Bishop CJ, Reis JN, Normark S, Henriques-Normark B, Covacci A, Rappuoli R, Barocchi MA. Moschioni M, et al. Among authors: donati c. J Infect Dis. 2008 Mar 15;197(6):888-96. doi: 10.1086/528375. J Infect Dis. 2008. PMID: 18269316
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells.
Bagnoli F, Moschioni M, Donati C, Dimitrovska V, Ferlenghi I, Facciotti C, Muzzi A, Giusti F, Emolo C, Sinisi A, Hilleringmann M, Pansegrau W, Censini S, Rappuoli R, Covacci A, Masignani V, Barocchi MA. Bagnoli F, et al. Among authors: donati c. J Bacteriol. 2008 Aug;190(15):5480-92. doi: 10.1128/JB.00384-08. Epub 2008 May 30. J Bacteriol. 2008. PMID: 18515415 Free PMC article.
The Streptococcus pneumoniae pilus-1 displays a biphasic expression pattern.
De Angelis G, Moschioni M, Muzzi A, Pezzicoli A, Censini S, Delany I, Lo Sapio M, Sinisi A, Donati C, Masignani V, Barocchi MA. De Angelis G, et al. Among authors: donati c. PLoS One. 2011;6(6):e21269. doi: 10.1371/journal.pone.0021269. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731688 Free PMC article.
An extended multi-locus molecular typing schema for Streptococcus pneumoniae demonstrates that a limited number of capsular switch events is responsible for serotype heterogeneity of closely related strains from different countries.
Crisafulli G, Guidotti S, Muzzi A, Torricelli G, Moschioni M, Masignani V, Censini S, Donati C. Crisafulli G, et al. Among authors: donati c. Infect Genet Evol. 2013 Jan;13:151-61. doi: 10.1016/j.meegid.2012.09.008. Epub 2012 Sep 27. Infect Genet Evol. 2013. PMID: 23022733
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species.
Donati C, Hiller NL, Tettelin H, Muzzi A, Croucher NJ, Angiuoli SV, Oggioni M, Dunning Hotopp JC, Hu FZ, Riley DR, Covacci A, Mitchell TJ, Bentley SD, Kilian M, Ehrlich GD, Rappuoli R, Moxon ER, Masignani V. Donati C, et al. Genome Biol. 2010;11(10):R107. doi: 10.1186/gb-2010-11-10-r107. Epub 2010 Oct 29. Genome Biol. 2010. PMID: 21034474 Free PMC article.
The microbial pan-genome.
Medini D, Donati C, Tettelin H, Masignani V, Rappuoli R. Medini D, et al. Among authors: donati c. Curr Opin Genet Dev. 2005 Dec;15(6):589-94. doi: 10.1016/j.gde.2005.09.006. Epub 2005 Sep 26. Curr Opin Genet Dev. 2005. PMID: 16185861 Review.
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