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Cholestatic pruritus: Emerging mechanisms and therapeutics.
Patel SP, Vasavda C, Ho B, Meixiong J, Dong X, Kwatra SG. Patel SP, et al. Among authors: dong x. J Am Acad Dermatol. 2019 Dec;81(6):1371-1378. doi: 10.1016/j.jaad.2019.04.035. Epub 2019 Apr 19. J Am Acad Dermatol. 2019. PMID: 31009666 Free PMC article.
A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice.
Wolf K, Kühn H, Boehm F, Gebhardt L, Glaudo M, Agelopoulos K, Ständer S, Ectors P, Zahn D, Riedel YK, Thimm D, Müller CE, Kretschmann S, Kremer AN, Chien D, Limjunyawong N, Peng Q, Dong X, Kolkhir P, Scheffel J, Søgaard ML, Weigmann B, Neurath MF, Hawro T, Metz M, Fischer MJM, Kremer AE. Wolf K, et al. Among authors: dong x. J Allergy Clin Immunol. 2021 Aug;148(2):506-522.e8. doi: 10.1016/j.jaci.2020.12.655. Epub 2021 Feb 20. J Allergy Clin Immunol. 2021. PMID: 33617860
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Zaufel A, van de Wiel SMW, Yin L, Fauler G, Chien D, Dong X, Gilmer JF, Truong JK, Dawson PA, van de Graaf SFJ, Fickert P, Moustafa T. Zaufel A, et al. Among authors: dong x. Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1;1867(8):166153. doi: 10.1016/j.bbadis.2021.166153. Epub 2021 Apr 22. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33895309 Free PMC article.
The cell biology of acute itch.
Green D, Dong X. Green D, et al. Among authors: dong x. J Cell Biol. 2016 Apr 25;213(2):155-61. doi: 10.1083/jcb.201603042. J Cell Biol. 2016. PMID: 27114499 Free PMC article. Review.
Neuropathic pruritus.
Kwatra SG, Kambala A, Dong X. Kwatra SG, et al. Among authors: dong x. J Allergy Clin Immunol. 2023 Jul;152(1):36-38. doi: 10.1016/j.jaci.2023.04.006. Epub 2023 Apr 23. J Allergy Clin Immunol. 2023. PMID: 37094766 No abstract available.
FAM19A1, a brain-enriched and metabolically responsive neurokine, regulates food intake patterns and mouse behaviors.
Lei X, Liu L, Terrillion CE, Karuppagounder SS, Cisternas P, Lay M, Martinelli DC, Aja S, Dong X, Pletnikov MV, Wong GW. Lei X, et al. Among authors: dong x. FASEB J. 2019 Dec;33(12):14734-14747. doi: 10.1096/fj.201901232RR. Epub 2019 Nov 5. FASEB J. 2019. PMID: 31689372 Free PMC article.
Our results establish an in vivo function of FAM19A1 and highlight central roles for this family of neurokines in modulating animal physiology and behavior.-Lei, X., Liu, L., Terrillion, C. E., Karuppagounder, S. S., Cisternas, P., Lay, M., Martinelli, D. C., Aja, S., D …
Our results establish an in vivo function of FAM19A1 and highlight central roles for this family of neurokines in modulating animal physiolo …
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