Douillard P - Search Results

1

The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction.

Miyake S, Lupher ML Jr, Andoniou CE, Lill NL, Ota S, Douillard P, Rao N, Band H. Miyake S, et al. Among authors: douillard p. Crit Rev Oncog. 1997;8(2-3):189-218. doi: 10.1615/critrevoncog.v8.i2-3.30. Crit Rev Oncog. 1997. PMID: 9570294 Review.

2

Negative regulation of Lck by Cbl ubiquitin ligase.

Rao N, Miyake S, Reddi AL, Douillard P, Ghosh AK, Dodge IL, Zhou P, Fernandes ND, Band H. Rao N, et al. Among authors: douillard p. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3794-9. doi: 10.1073/pnas.062055999. Proc Natl Acad Sci U S A. 2002. PMID: 11904433 Free PMC article.

3

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain.

Miyake S, Mullane-Robinson KP, Lill NL, Douillard P, Band H. Miyake S, et al. Among authors: douillard p. J Biol Chem. 1999 Jun 4;274(23):16619-28. doi: 10.1074/jbc.274.23.16619. J Biol Chem. 1999. PMID: 10347229 Free article.

4

The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor.

Lill NL, Douillard P, Awwad RA, Ota S, Lupher ML Jr, Miyake S, Meissner-Lula N, Hsu VW, Band H. Lill NL, et al. Among authors: douillard p. J Biol Chem. 2000 Jan 7;275(1):367-77. doi: 10.1074/jbc.275.1.367. J Biol Chem. 2000. PMID: 10617627 Free article.

5

An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn.

Rao N, Ghosh AK, Douillard P, Andoniou CE, Zhou P, Band H. Rao N, et al. Among authors: douillard p. Signal Transduct. 2002 Nov 7;2(1-2):29-39. doi: 10.1002/1615-4061(200205)2:1/2<29::AID-SITA29>3.0.CO;2-7. Signal Transduct. 2002. PMID: 19966925 Free PMC article.

6

Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.

Reddi AL, Ying G, Duan L, Chen G, Dimri M, Douillard P, Druker BJ, Naramura M, Band V, Band H. Reddi AL, et al. Among authors: douillard p. J Biol Chem. 2007 Oct 5;282(40):29336-47. doi: 10.1074/jbc.M701797200. Epub 2007 Jul 9. J Biol Chem. 2007. PMID: 17620338 Free article.

7

Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics.

Douillard P, Freissmuth M, Antoine G, Thiele M, Fleischanderl D, Matthiessen P, Voelkel D, Kerschbaumer RJ, Scheiflinger F, Sabarth N. Douillard P, et al. Antibodies (Basel). 2019 Sep 6;8(3):46. doi: 10.3390/antib8030046. Antibodies (Basel). 2019. PMID: 31544852 Free PMC article.

8

Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch.

Schinagl A, Kerschbaumer RJ, Sabarth N, Douillard P, Scholz P, Voelkel D, Hollerweger JC, Goettig P, Brandstetter H, Scheiflinger F, Thiele M. Schinagl A, et al. Among authors: douillard p. Biochemistry. 2018 Mar 6;57(9):1523-1532. doi: 10.1021/acs.biochem.7b01156. Epub 2018 Feb 15. Biochemistry. 2018. PMID: 29412660

9

Pharmacokinetics, disease-modifying activity, and safety of an experimental therapeutic targeting an immunological isoform of macrophage migration inhibitory factor, in rat glomerulonephritis.

Höllriegl W, Bauer A, Baumgartner B, Dietrich B, Douillard P, Kerschbaumer RJ, Höbarth G, McKee JS, Schinagl A, Tam FWK, Thiele M, Weber A, Wolfsegger M, Turecek M, Muchitsch EM, Scheiflinger F, Glantschnig H. Höllriegl W, et al. Among authors: douillard p. Eur J Pharmacol. 2018 Feb 5;820:206-216. doi: 10.1016/j.ejphar.2017.12.040. Epub 2017 Dec 20. Eur J Pharmacol. 2018. PMID: 29274331 Free article.

10

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer.

Schinagl A, Thiele M, Douillard P, Völkel D, Kenner L, Kazemi Z, Freissmuth M, Scheiflinger F, Kerschbaumer RJ. Schinagl A, et al. Among authors: douillard p. Oncotarget. 2016 Nov 8;7(45):73486-73496. doi: 10.18632/oncotarget.11970. Oncotarget. 2016. PMID: 27636991 Free PMC article.

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