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Therapeutic immunisation plus cytokine and hormone therapy improves CD4 T-cell counts, restores anti-HIV-1 responses and reduces immune activation in treated chronic HIV-1 infection.
Herasimtschuk A, Downey J, Nelson M, Moyle G, Mandalia S, Sikut R, Adojaan M, Stanescu I, Gotch F, Imami N. Herasimtschuk A, et al. Among authors: downey j. Vaccine. 2014 Dec 5;32(51):7005-7013. doi: 10.1016/j.vaccine.2014.09.072. Epub 2014 Oct 22. Vaccine. 2014. PMID: 25454870 Free article. Clinical Trial.
T-cell signalling and immune system disorders.
Wilkinson B, Downey JS, Rudd CE. Wilkinson B, et al. Expert Rev Mol Med. 2005 Dec 19;7(29):1-29. doi: 10.1017/S1462399405010264. Expert Rev Mol Med. 2005. PMID: 16364187 Review.
Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist.
Thaventhiran T, Alhumeed N, Yeang HX, Sethu S, Downey JS, Alghanem AF, Olayanju A, Smith EL, Cross MJ, Webb SD, Williams DP, Bristow A, Ball C, Stebbings R, Sathish JG. Thaventhiran T, et al. Among authors: downey js. MAbs. 2014;6(5):1290-9. doi: 10.4161/mabs.29758. Epub 2014 Oct 30. MAbs. 2014. PMID: 25517314 Free PMC article.
Gene suppression by tristetraprolin and release by the p38 pathway.
Zhu W, Brauchle MA, Di Padova F, Gram H, New L, Ono K, Downey JS, Han J. Zhu W, et al. Among authors: downey js. Am J Physiol Lung Cell Mol Physiol. 2001 Aug;281(2):L499-508. doi: 10.1152/ajplung.2001.281.2.L499. Am J Physiol Lung Cell Mol Physiol. 2001. PMID: 11435226 Free article.
734 results