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AS602868, a dual inhibitor of IKK2 and FLT3 to target AML cells.
Griessinger E, Imbert V, Lagadec P, Gonthier N, Dubreuil P, Romanelli A, Dreano M, Peyron JF. Griessinger E, et al. Among authors: dreano m. Leukemia. 2007 May;21(5):877-85. doi: 10.1038/sj.leu.2404614. Epub 2007 Mar 1. Leukemia. 2007. PMID: 17330097
Preclinical targeting of NF-kappaB and FLT3 pathways in AML cells.
Griessinger E, Frelin C, Cuburu N, Imbert V, Dageville C, Hummelsberger M, Sirvent N, Dreano M, Peyron JF. Griessinger E, et al. Among authors: dreano m. Leukemia. 2008 Jul;22(7):1466-9. doi: 10.1038/sj.leu.2405102. Epub 2008 Jan 31. Leukemia. 2008. PMID: 18239622 No abstract available.
Inhibition of IkappaB kinase subunit 2 in cutaneous T-cell lymphoma down-regulates nuclear factor-kappaB constitutive activation, induces cell death, and potentiates the apoptotic response to antineoplastic chemotherapeutic agents.
Sors A, Jean-Louis F, Bégué E, Parmentier L, Dubertret L, Dreano M, Courtois G, Bachelez H, Michel L. Sors A, et al. Among authors: dreano m. Clin Cancer Res. 2008 Feb 1;14(3):901-11. doi: 10.1158/1078-0432.CCR-07-1419. Clin Cancer Res. 2008. PMID: 18245554
37 results