Dreyer GB - Search Results

1

Peptide substrates and inhibitors of the HIV-1 protease.

Moore ML, Bryan WM, Fakhoury SA, Magaard VW, Huffman WF, Dayton BD, Meek TD, Hyland L, Dreyer GB, Metcalf BW, et al. Moore ML, et al. Among authors: dreyer gb. Biochem Biophys Res Commun. 1989 Mar 15;159(2):420-5. doi: 10.1016/0006-291x(89)90008-9. Biochem Biophys Res Commun. 1989. PMID: 2649094

2

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues.

Meek TD, Lambert DM, Dreyer GB, Carr TJ, Tomaszek TA Jr, Moore ML, Strickler JE, Debouck C, Hyland LJ, Matthews TJ, et al. Meek TD, et al. Among authors: dreyer gb. Nature. 1990 Jan 4;343(6253):90-2. doi: 10.1038/343090a0. Nature. 1990. PMID: 1688646

3

HIV-1 protease as a potential target for anti-AIDS therapy.

Meek TD, Dreyer GB. Meek TD, et al. Among authors: dreyer gb. Ann N Y Acad Sci. 1990;616:41-53. doi: 10.1111/j.1749-6632.1990.tb17826.x. Ann N Y Acad Sci. 1990. PMID: 2078031 Review. No abstract available.

4

Human immunodeficiency virus 1 protease expressed in Escherichia coli behaves as a dimeric aspartic protease.

Meek TD, Dayton BD, Metcalf BW, Dreyer GB, Strickler JE, Gorniak JG, Rosenberg M, Moore ML, Magaard VW, Debouck C. Meek TD, et al. Among authors: dreyer gb. Proc Natl Acad Sci U S A. 1989 Mar;86(6):1841-5. doi: 10.1073/pnas.86.6.1841. Proc Natl Acad Sci U S A. 1989. PMID: 2648384 Free PMC article.

5

Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors.

Dreyer GB, Metcalf BW, Tomaszek TA Jr, Carr TJ, Chandler AC 3rd, Hyland L, Fakhoury SA, Magaard VW, Moore ML, Strickler JE, et al. Dreyer GB, et al. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9752-6. doi: 10.1073/pnas.86.24.9752. Proc Natl Acad Sci U S A. 1989. PMID: 2690072 Free PMC article.

6

Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease.

Tomaszek TA Jr, Moore ML, Strickler JE, Sanchez RL, Dixon JS, Metcalf BW, Hassell A, Dreyer GB, Brooks I, Debouck C, et al. Tomaszek TA Jr, et al. Among authors: dreyer gb. Biochemistry. 1992 Oct 27;31(42):10153-68. doi: 10.1021/bi00157a003. Biochemistry. 1992. PMID: 1420138

7

Human immunodeficiency virus type 1 protease inhibitors irreversibly block infectivity of purified virions from chronically infected cells.

Lambert DM, Petteway SR Jr, McDanal CE, Hart TK, Leary JJ, Dreyer GB, Meek TD, Bugelski PJ, Bolognesi DP, Metcalf BW, et al. Lambert DM, et al. Among authors: dreyer gb. Antimicrob Agents Chemother. 1992 May;36(5):982-8. doi: 10.1128/AAC.36.5.982. Antimicrob Agents Chemother. 1992. PMID: 1510424 Free PMC article.

8

Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays.

Dreyer GB, Lambert DM, Meek TD, Carr TJ, Tomaszek TA Jr, Fernandez AV, Bartus H, Cacciavillani E, Hassell AM, Minnich M, et al. Dreyer GB, et al. Biochemistry. 1992 Jul 28;31(29):6646-59. doi: 10.1021/bi00144a004. Biochemistry. 1992. PMID: 1637805

9

Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease.

Grant SK, Deckman IC, Minnich MD, Culp J, Franklin S, Dreyer GB, Tomaszek TA Jr, Debouck C, Meek TD. Grant SK, et al. Among authors: dreyer gb. Biochemistry. 1991 Aug 27;30(34):8424-34. doi: 10.1021/bi00098a021. Biochemistry. 1991. PMID: 1883829

10

Synergistic drug interactions of an HIV-1 protease inhibitor with AZT in different in vitro models of HIV-1 infection.

Lambert DM, Bartus H, Fernandez AV, Bratby-Anders C, Leary JJ, Dreyer GB, Metcalf BW, Petteway SR Jr. Lambert DM, et al. Among authors: dreyer gb. Antiviral Res. 1993 Aug;21(4):327-42. doi: 10.1016/0166-3542(93)90011-7. Antiviral Res. 1993. PMID: 7692816

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