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Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction.
Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Drosatos K, et al. Among authors: drosatos tampakaki z. J Biol Chem. 2011 Oct 21;286(42):36331-9. doi: 10.1074/jbc.M111.272146. Epub 2011 Aug 26. J Biol Chem. 2011. PMID: 21873422 Free PMC article.
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, Goldberg IJ, Schulze PC. Chokshi A, et al. Among authors: drosatos k. Circulation. 2012 Jun 12;125(23):2844-53. doi: 10.1161/CIRCULATIONAHA.111.060889. Epub 2012 May 14. Circulation. 2012. PMID: 22586279 Free PMC article.
Adipose-specific lipoprotein lipase deficiency more profoundly affects brown than white fat biology.
Garcia-Arcos I, Hiyama Y, Drosatos K, Bharadwaj KG, Hu Y, Son NH, O'Byrne SM, Chang CL, Deckelbaum RJ, Takahashi M, Westerterp M, Obunike JC, Jiang H, Yagyu H, Blaner WS, Goldberg IJ. Garcia-Arcos I, et al. Among authors: drosatos k. J Biol Chem. 2013 May 17;288(20):14046-14058. doi: 10.1074/jbc.M113.469270. Epub 2013 Mar 31. J Biol Chem. 2013. PMID: 23542081 Free PMC article.
Lipid Use and Misuse by the Heart.
Schulze PC, Drosatos K, Goldberg IJ. Schulze PC, et al. Among authors: drosatos k. Circ Res. 2016 May 27;118(11):1736-51. doi: 10.1161/CIRCRESAHA.116.306842. Circ Res. 2016. PMID: 27230639 Free PMC article. Review.
63 results