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Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Cho Y, et al. Among authors: du x. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. doi: 10.1073/pnas.1002716107. Epub 2010 Jun 8. Proc Natl Acad Sci U S A. 2010. PMID: 20534506 Free PMC article.
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).
Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, Fan J, Lue H, Chen Y, Xiong H, Chagnon F, Bernhagen J, Lolis E, Mor G, Lesur O, Bucala R. Merk M, et al. Among authors: du x. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E577-85. doi: 10.1073/pnas.1102941108. Epub 2011 Aug 4. Proc Natl Acad Sci U S A. 2011. PMID: 21817065 Free PMC article.
Receptor agonists of macrophage migration inhibitory factor.
Jorgensen WL, Gandavadi S, Du X, Hare AA, Trofimov A, Leng L, Bucala R. Jorgensen WL, et al. Among authors: du x. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7033-6. doi: 10.1016/j.bmcl.2010.09.118. Epub 2010 Sep 29. Bioorg Med Chem Lett. 2010. PMID: 20971005 Free PMC article.
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