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Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.
Hum Mol Genet. 2012 Apr 15;21(8):1861-76. doi: 10.1093/hmg/ddr618. Epub 2012 Jan 12.
Hum Mol Genet. 2012.
PMID: 22246294
Free PMC article.
Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease.
Dusonchet J, Bensadoun JC, Schneider BL, Aebischer P.
Dusonchet J, et al.
Neurobiol Dis. 2009 Jul;35(1):32-41. doi: 10.1016/j.nbd.2009.03.013. Epub 2009 Apr 5.
Neurobiol Dis. 2009.
PMID: 19348945
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A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2.
Dusonchet J, Kochubey O, Stafa K, Young SM Jr, Zufferey R, Moore DJ, Schneider BL, Aebischer P.
Dusonchet J, et al.
J Neurosci. 2011 Jan 19;31(3):907-12. doi: 10.1523/JNEUROSCI.5092-10.2011.
J Neurosci. 2011.
PMID: 21248115
Free PMC article.
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A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity.
Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, Yue Z, Bandopadhyay R, Glicksman MA, Moore DJ, Collins JJ, Wolozin B.
Dusonchet J, et al.
Hum Mol Genet. 2014 Sep 15;23(18):4887-905. doi: 10.1093/hmg/ddu202. Epub 2014 May 2.
Hum Mol Genet. 2014.
PMID: 24794857
Free PMC article.
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Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease.
Tsika E, Nguyen AP, Dusonchet J, Colin P, Schneider BL, Moore DJ.
Tsika E, et al. Among authors: dusonchet j.
Neurobiol Dis. 2015 May;77:49-61. doi: 10.1016/j.nbd.2015.02.019. Epub 2015 Feb 28.
Neurobiol Dis. 2015.
PMID: 25731749
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Exogenous LRRK2G2019S induces parkinsonian-like pathology in a nonhuman primate.
Mestre-Francés N, Serratrice N, Gennetier A, Devau G, Cobo S, Trouche SG, Fontès P, Zussy C, De Deurwaerdere P, Salinas S, Mennechet FJ, Dusonchet J, Schneider BL, Saggio I, Kalatzis V, Luquin-Piudo MR, Verdier JM, Kremer EJ.
Mestre-Francés N, et al. Among authors: dusonchet j.
JCI Insight. 2018 Jul 26;3(14):e98202. doi: 10.1172/jci.insight.98202. eCollection 2018 Jul 26.
JCI Insight. 2018.
PMID: 30046008
Free PMC article.
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Interaction of LRRK2 with kinase and GTPase signaling cascades.
Boon JY, Dusonchet J, Trengrove C, Wolozin B.
Boon JY, et al. Among authors: dusonchet j.
Front Mol Neurosci. 2014 Jul 9;7:64. doi: 10.3389/fnmol.2014.00064. eCollection 2014.
Front Mol Neurosci. 2014.
PMID: 25071441
Free PMC article.
Review.
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Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux.
Tarasov A, Dusonchet J, Ashcroft F.
Tarasov A, et al. Among authors: dusonchet j.
Diabetes. 2004 Dec;53 Suppl 3:S113-22. doi: 10.2337/diabetes.53.suppl_3.s113.
Diabetes. 2004.
PMID: 15561898
Review.
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