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Year Number of Results
1997 1
1998 1
2003 4
2004 2
2005 2
2006 2
2008 2
2010 1
2011 1
2012 2
2013 3
2015 6
2016 2
2017 6
2018 2
2019 3
2020 4
2021 5
2022 5
2023 9
2024 0

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60 results

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Page 1
DUSP7: an Unusual Player in Adverse Cardiac Remodeling.
Xu GE, Song J, Gokulnath P, Vulugundam G, Xiao J. Xu GE, et al. J Cardiovasc Transl Res. 2022 Dec;15(6):1217-1218. doi: 10.1007/s12265-022-10274-5. Epub 2022 May 19. J Cardiovasc Transl Res. 2022. PMID: 35588349 No abstract available.
DUSP7 inhibits cervical cancer progression by inactivating the RAS pathway.
Bai H, Song M, Jiao R, Li W, Zhao J, Xiao M, Jin M, Zhang Z, Deng H. Bai H, et al. J Cell Mol Med. 2021 Oct;25(19):9306-9318. doi: 10.1111/jcmm.16865. Epub 2021 Aug 26. J Cell Mol Med. 2021. PMID: 34435746 Free PMC article.
The expression of HRAS and p-ERK1/2 was decreased in DUSP7-SIHA cells compared with NC-SIHA cells (p = 0.0003 and 0.0026). ...DUSP7 inhibits cervical cancer progression by inactivating the RAS pathway....
The expression of HRAS and p-ERK1/2 was decreased in DUSP7-SIHA cells compared with NC-SIHA cells (p = 0.0003 and 0.0026). ...DUSP …
DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division.
Guo X, Ramirez I, Garcia YA, Velasquez EF, Gholkar AA, Cohn W, Whitelegge JP, Tofig B, Damoiseaux R, Torres JZ. Guo X, et al. J Biol Chem. 2021 Jan-Jun;296:100676. doi: 10.1016/j.jbc.2021.100676. Epub 2021 Apr 16. J Biol Chem. 2021. PMID: 33865857 Free PMC article.
During mitosis, DUSP7 bound to ERK2 and regulated the abundance of active phospho-ERK2 through its phosphatase activity. Overexpression of DUSP7, but not catalytically inactive mutants, led to a decrease in the levels of phospho-ERK2 and mitotic chromosome misalignm …
During mitosis, DUSP7 bound to ERK2 and regulated the abundance of active phospho-ERK2 through its phosphatase activity. Overexpressi …
Targeting DUSP7 signaling alleviates hepatic steatosis, inflammation and oxidative stress in high fat diet (HFD)-fed mice via suppression of TAK1.
Wu L, Liu Y, Zhao Y, Li M, Guo L. Wu L, et al. Free Radic Biol Med. 2020 Jun;153:140-158. doi: 10.1016/j.freeradbiomed.2020.04.009. Epub 2020 Apr 18. Free Radic Biol Med. 2020. PMID: 32311490
However, the effects of DUSP7 on hepatic steatosis are still not fully understood. Here, we found that DUSP7 functioned as a negative regulator of NAFLD and in various metabolic disorders. ...Thus, we may provide an effective strategy for the treatment of hepatic st …
However, the effects of DUSP7 on hepatic steatosis are still not fully understood. Here, we found that DUSP7 functioned as a n …
Identification of DUSP7 as an RNA Marker for Prognostic Stratification in Acute Myeloid Leukemia: Evidence from Large Population Cohorts.
Gao X. Gao X. Genet Res (Camb). 2023 Jul 26;2023:4348290. doi: 10.1155/2023/4348290. eCollection 2023. Genet Res (Camb). 2023. PMID: 37538139 Free PMC article.
Biological enrichment analysis and immune-related analysis were performed to illustrate the role of DUSP7 in AML. Single-cell analysis indicated that the DUSP7 was widely distributed in various cells, especially in monocyte/macrophages and malignant. ...CONCLUSIONS: …
Biological enrichment analysis and immune-related analysis were performed to illustrate the role of DUSP7 in AML. Single-cell analysi …
The Phosphatase Dusp7 Drives Meiotic Resumption and Chromosome Alignment in Mouse Oocytes.
Tischer T, Schuh M. Tischer T, et al. Cell Rep. 2016 Oct 25;17(5):1426-1437. doi: 10.1016/j.celrep.2016.10.007. Cell Rep. 2016. PMID: 27783954 Free PMC article.
Here, we identify and characterize an essential pathway for the resumption of meiosis that relies on the protein phosphatase DUSP7. DUSP7-depleted oocytes either fail to resume meiosis or resume meiosis with a significant delay. ...In addition to controlling meiotic …
Here, we identify and characterize an essential pathway for the resumption of meiosis that relies on the protein phosphatase DUSP7. …
Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis.
Yang W, Gong P, Yang Y, Yang C, Yang B, Ren L. Yang W, et al. Cancer Manag Res. 2020 Mar 27;12:2327-2337. doi: 10.2147/CMAR.S238513. eCollection 2020. Cancer Manag Res. 2020. PMID: 32273769 Free PMC article.
The protein expression of DUSP7 was examined by Western blot assay. Murine xenograft model was established to confirm the role of circ-ABCB10 in vivo. ...CONCLUSION: Circ-ABCB10 mediated PTX resistance, apoptosis, invasion and autophagy of BC cells via let-7a-5p/DUSP7 …
The protein expression of DUSP7 was examined by Western blot assay. Murine xenograft model was established to confirm the role of cir …
Transcription Factor FOSL1 Enhances Drug Resistance of Breast Cancer through DUSP7-Mediated Dephosphorylation of PEA15.
Li L, Wang N, Xiong Y, Guo G, Zhu M, Gu Y. Li L, et al. Mol Cancer Res. 2022 Apr 1;20(4):515-526. doi: 10.1158/1541-7786.MCR-21-0658. Mol Cancer Res. 2022. PMID: 34907034
It positively regulated the transcription of dual specificity phosphatase 7 (DUSP7) in breast cancer doxorubicin-resistant cells and DUSP7 also enhanced the drug resistance of breast cancer cells. Furthermore, FOSL1 promoted the dephosphorylation of proliferation an …
It positively regulated the transcription of dual specificity phosphatase 7 (DUSP7) in breast cancer doxorubicin-resistant cells and …
Loss of SETD2 aggravates colorectal cancer progression caused by SMAD4 deletion through the RAS/ERK signalling pathway.
Ma C, Liu M, Feng W, Rao H, Zhang W, Liu C, Xu Y, Wang Z, Teng Y, Yang X, Ni L, Xu J, Gao WQ, Lu B, Li L. Ma C, et al. Clin Transl Med. 2023 Nov;13(11):e1475. doi: 10.1002/ctm2.1475. Clin Transl Med. 2023. PMID: 37962020 Free PMC article.
Further mechanistic findings revealed that the loss of SETD2 resulted in the down-regulation of DUSP7, which is involved in the inhibition of the RAS/ERK signalling pathway. Finally, the ERK1/2 inhibitor SCH772984 significantly attenuated the progression of CRC in Smad4(Vi …
Further mechanistic findings revealed that the loss of SETD2 resulted in the down-regulation of DUSP7, which is involved in the inhib …
Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia.
Ham JE, Oh EK, Kim DH, Choi SH. Ham JE, et al. Biochem Biophys Res Commun. 2015 Nov 13;467(2):254-60. doi: 10.1016/j.bbrc.2015.09.180. Epub 2015 Oct 3. Biochem Biophys Res Commun. 2015. PMID: 26435497
The expression of DUSP6 and DUSP7 was regulated inverse to the phosphorylation of ERK1/2 in LPS-stimulated microglia. ...The expression of DUPS6 and DUSP7 was mediated by ERK1/2 activity both in resting and LPS-stimulated microglia. ...
The expression of DUSP6 and DUSP7 was regulated inverse to the phosphorylation of ERK1/2 in LPS-stimulated microglia. ...The expressi …
60 results