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Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243.
Dutca LM, Stasheff SF, Hedberg-Buenz A, Rudd DS, Batra N, Blodi FR, Yorek MS, Yin T, Shankar M, Herlein JA, Naidoo J, Morlock L, Williams N, Kardon RH, Anderson MG, Pieper AA, Harper MM. Dutca LM, et al. Invest Ophthalmol Vis Sci. 2014 Dec 2;55(12):8330-41. doi: 10.1167/iovs.14-15468. Invest Ophthalmol Vis Sci. 2014. PMID: 25468886 Free PMC article.
P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury.
Yin TC, Britt JK, De Jesús-Cortés H, Lu Y, Genova RM, Khan MZ, Voorhees JR, Shao J, Katzman AC, Huntington PJ, Wassink C, McDaniel L, Newell EA, Dutca LM, Naidoo J, Cui H, Bassuk AG, Harper MM, McKnight SL, Ready JM, Pieper AA. Yin TC, et al. Among authors: dutca lm. Cell Rep. 2014 Sep 25;8(6):1731-1740. doi: 10.1016/j.celrep.2014.08.030. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220467 Free PMC article.
(-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia.
Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA. Voorhees JR, et al. Among authors: dutca lm. Biol Psychiatry. 2018 Oct 1;84(7):488-498. doi: 10.1016/j.biopsych.2017.10.023. Epub 2017 Nov 6. Biol Psychiatry. 2018. PMID: 29246437 Free PMC article.
Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury.
Harper MM, Woll AW, Evans LP, Delcau M, Akurathi A, Hedberg-Buenz A, Soukup DA, Boehme N, Hefti MM, Dutca LM, Anderson MG, Bassuk AG. Harper MM, et al. Among authors: dutca lm. Invest Ophthalmol Vis Sci. 2019 Oct 1;60(13):4159-4170. doi: 10.1167/iovs.19-27565. Invest Ophthalmol Vis Sci. 2019. PMID: 31598627 Free PMC article.
Identification of chronic brain protein changes and protein targets of serum auto-antibodies after blast-mediated traumatic brain injury.
Harper MM, Rudd D, Meyer KJ, Kanthasamy AG, Anantharam V, Pieper AA, Vázquez-Rosa E, Shin MK, Chaubey K, Koh Y, Evans LP, Bassuk AG, Anderson MG, Dutca L, Kudva IT, John M. Harper MM, et al. Heliyon. 2020 Feb 17;6(2):e03374. doi: 10.1016/j.heliyon.2020.e03374. eCollection 2020 Feb. Heliyon. 2020. PMID: 32099918 Free PMC article.
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