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Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.
Liu MC, Luo MZ, Mozdziesz DE, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC. Liu MC, et al. Among authors: dutschman ge. Nucleosides Nucleotides Nucleic Acids. 2005;24(2):135-45. doi: 10.1081/NCN-51898. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15822619
Synthesis and antiviral activity of helioxanthin analogues.
Yeo H, Li Y, Fu L, Zhu JL, Gullen EA, Dutschman GE, Lee Y, Chung R, Huang ES, Austin DJ, Cheng YC. Yeo H, et al. Among authors: dutschman ge. J Med Chem. 2005 Jan 27;48(2):534-46. doi: 10.1021/jm034265a. J Med Chem. 2005. PMID: 15658867
Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro.
Lin TS, Luo MZ, Liu MC, Zhu YL, Gullen E, Dutschman GE, Cheng YC. Lin TS, et al. Among authors: dutschman ge. J Med Chem. 1996 Apr 26;39(9):1757-9. doi: 10.1021/jm950836q. J Med Chem. 1996. PMID: 8627596 No abstract available.
87 results