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1984 2
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2007 4
2008 5
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2012 13
2013 14
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219 results

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Page 1
EBF1 promotes triple-negative breast cancer progression by surveillance of the HIF1alpha pathway.
Qiu Z, Guo W, Dong B, Wang Y, Deng P, Wang C, Liu J, Zhang Q, Grosschedl R, Yu Z, Deng J, Wu Y. Qiu Z, et al. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2119518119. doi: 10.1073/pnas.2119518119. Epub 2022 Jul 8. Proc Natl Acad Sci U S A. 2022. PMID: 35867755 Free PMC article.
However, the functional roles of EBF1 in tumorigenesis remain elusive. Here, we demonstrate that EBF1 is highly expressed in triple-negative breast cancer (TNBC). ...Our findings reveal a key function for EBF1 as a master regulator of mitochondria home …
However, the functional roles of EBF1 in tumorigenesis remain elusive. Here, we demonstrate that EBF1 is highly expressed in t …
Breast cancer-derived exosomal lncRNA SNHG14 induces normal fibroblast activation to cancer-associated fibroblasts via the EBF1/FAM171A1 axis.
Dong H, Yang C, Chen X, Sun H, He X, Wang W. Dong H, et al. Breast Cancer. 2023 Nov;30(6):1028-1040. doi: 10.1007/s12282-023-01496-9. Epub 2023 Aug 31. Breast Cancer. 2023. PMID: 37653187
METHODS: Adjacent normal tissues, cancerous and serum specimens were gathered in breast cancer patients. ...CONCLUSION: Breast cancer-derived exosomal SNHG14 contributed to NFs transformation into CAFs by the EBF1/FAM171A1 axis....
METHODS: Adjacent normal tissues, cancerous and serum specimens were gathered in breast cancer patients. ...CONCLUSION: Breast …
Circ_0022340 promotes colorectal cancer progression via HNRNPC/EBF1/SYT7 or miR-382-5p/ELK1 axis.
Liu Z, Xu X, Chen D, Zhang L, Pan Y, Liu D, Shen M, Chen M. Liu Z, et al. Cell Mol Biol (Noisy-le-grand). 2022 Jul 31;68(7):107-116. doi: 10.14715/cmb/2022.68.7.18. Cell Mol Biol (Noisy-le-grand). 2022. PMID: 36495510
Circular RNAs (circRNAs) are characterized as a class of new noncoding RNAs and function in tumorigenesis of colorectal cancer (CRC). In our study, the molecule mechanism of circ_0022340 in CRC was investigated. ...It is concluded that Circ_0022340 promoted colorectal c …
Circular RNAs (circRNAs) are characterized as a class of new noncoding RNAs and function in tumorigenesis of colorectal cancer (CRC). …
LINC00261 regulates EBF1 to suppress malignant progression of thyroid cancer.
Fu XD, Liu CY, Liu YL, Su DW, Chi NN, Zhang JL, Wei WW. Fu XD, et al. Eur Rev Med Pharmacol Sci. 2021 Dec;25(24):7626-7634. doi: 10.26355/eurrev_202112_27609. Eur Rev Med Pharmacol Sci. 2021. PMID: 34982424 Free article.
Bioinformatics analysis suggested that LINC00261 could target EBF1. Luciferase reporter gene experiment and qRT-PCR analysis suggested that LINC00261 could target EBF1 and that their expressions showed a negative correlation in TC tumor tissues and cells. ...Subsequ …
Bioinformatics analysis suggested that LINC00261 could target EBF1. Luciferase reporter gene experiment and qRT-PCR analysis suggeste …
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer.
Xing M, Ooi WF, Tan J, Qamra A, Lee PH, Li Z, Xu C, Padmanabhan N, Lim JQ, Guo YA, Yao X, Amit M, Ng LM, Sheng T, Wang J, Huang KK, Anene-Nzelu CG, Ho SWT, Ray M, Ma L, Fazzi G, Lim KJ, Wijaya GC, Zhang S, Nandi T, Yan T, Chang MM, Das K, Isa ZFA, Wu J, Poon PSY, Lam YN, Lin JS, Tay ST, Lee MH, Tan ALK, Ong X, White K, Rozen SG, Beer M, Foo RSY, Grabsch HI, Skanderup AJ, Li S, Teh BT, Tan P. Xing M, et al. J Clin Invest. 2020 Jun 1;130(6):3005-3020. doi: 10.1172/JCI126726. J Clin Invest. 2020. PMID: 32364535 Free PMC article.
Transcriptional reactivation of telomerase catalytic subunit (TERT) is a frequent hallmark of cancer, occurring in 90% of human malignancies. However, specific mechanisms driving TERT reactivation remain obscure for many tumor types and in particular gastric cancer …
Transcriptional reactivation of telomerase catalytic subunit (TERT) is a frequent hallmark of cancer, occurring in 90% of human malig …
TMPO-AS1/miR-98-5p/EBF1 feedback loop contributes to the progression of bladder cancer.
Luo H, Yang L, Liu C, Wang X, Dong Q, Liu L, Wei Q. Luo H, et al. Int J Biochem Cell Biol. 2020 May;122:105702. doi: 10.1016/j.biocel.2020.105702. Epub 2020 Feb 19. Int J Biochem Cell Biol. 2020. PMID: 32087328
LncRNA TMPO antisense RNA 1 (TMPO-AS1) has been confirmed to be implicated in the development of several cancers. However, its clinical significance is still largely unknown in bladder cancer (BCa). ...According to the results of rescue experiments, we observed that …
LncRNA TMPO antisense RNA 1 (TMPO-AS1) has been confirmed to be implicated in the development of several cancers. However, its clinic …
[EBF1 Promotes the Sensitivity of Cervical Cancer Cells to Cisplatin via Activating FBN1 Transcription].
Shen NN, Lin JH, Liu PP. Shen NN, et al. Mol Biol (Mosk). 2023 May-Jun;57(3):503-504. Mol Biol (Mosk). 2023. PMID: 37326054 Russian.
Moreover, the interaction between EBF1 and FBN1 was predicted and demonstrated. Finally, to further verify the EBF1/FB1-dependent mechanism of DDP sensitivity regulation in CC cells a xenograft mouse model of CC was established using SiHa-DDP cells transduced with l …
Moreover, the interaction between EBF1 and FBN1 was predicted and demonstrated. Finally, to further verify the EBF1/FB1-depend …
EBF1-Mediated Upregulation of Ribosome Assembly Factor PNO1 Contributes to Cancer Progression by Negatively Regulating the p53 Signaling Pathway.
Shen A, Chen Y, Liu L, Huang Y, Chen H, Qi F, Lin J, Shen Z, Wu X, Wu M, Li Q, Qiu L, Yu N, Sferra TJ, Peng J. Shen A, et al. Cancer Res. 2019 May 1;79(9):2257-2270. doi: 10.1158/0008-5472.CAN-18-3238. Epub 2019 Mar 12. Cancer Res. 2019. PMID: 30862720
In colorectal cancer tissues, the expression of EBF1 correlated inversely with PNO1. Data mining of online breast and lung cancer databases showed increased PNO1 expression and association with poor patient survival; PNO1 knockdown reduced cell viability of c …
In colorectal cancer tissues, the expression of EBF1 correlated inversely with PNO1. Data mining of online breast and lung …
Single-cell analysis identifies dynamic gene expression networks that govern B cell development and transformation.
Lee RD, Munro SA, Knutson TP, LaRue RS, Heltemes-Harris LM, Farrar MA. Lee RD, et al. Nat Commun. 2021 Nov 25;12(1):6843. doi: 10.1038/s41467-021-27232-5. Nat Commun. 2021. PMID: 34824268 Free PMC article.
These changes correlate with reciprocal changes in expression of the transcription factor EBF1 and the RNA binding protein YBX3, that are defining features of the pre-BCR-dependent stage. ...
These changes correlate with reciprocal changes in expression of the transcription factor EBF1 and the RNA binding protein YBX3, that …
Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation.
Viny AD, Bowman RL, Liu Y, Lavallée VP, Eisman SE, Xiao W, Durham BH, Navitski A, Park J, Braunstein S, Alija B, Karzai A, Csete IS, Witkin M, Azizi E, Baslan T, Ott CJ, Pe'er D, Dekker J, Koche R, Levine RL. Viny AD, et al. Cell Stem Cell. 2019 Nov 7;25(5):682-696.e8. doi: 10.1016/j.stem.2019.08.003. Epub 2019 Sep 5. Cell Stem Cell. 2019. PMID: 31495782 Free PMC article.
Transcriptional regulators, including the cohesin complex member STAG2, are recurrently mutated in cancer. The role of STAG2 in gene regulation, hematopoiesis, and tumor suppression remains unresolved. ...Although concurrent loss of Stag2 and Stag1 abrogated hematopoiesis, …
Transcriptional regulators, including the cohesin complex member STAG2, are recurrently mutated in cancer. The role of STAG2 in gene …
219 results