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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1996 1
1999 2
2000 1
2002 1
2003 1
2008 1
2011 1
2012 2
2013 1
2014 2
2015 4
2016 2
2017 1
2019 2
2020 1
2021 4
2023 1
2024 0

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28 results

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Page 1
The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer.
Ji Y, Zhang W, Shen K, Su R, Liu X, Ma Z, Liu B, Hu C, Xue Y, Xin Z, Yang Y, Li A, Jiang Z, Jing N, Zhu HH, Dong L, Zhu Y, Dong B, Pan J, Wang Q, Xue W. Ji Y, et al. Nat Commun. 2023 Nov 28;14(1):7794. doi: 10.1038/s41467-023-43676-3. Nat Commun. 2023. PMID: 38016952 Free PMC article.
Uncovering the oncogenic mechanisms could lead to the discovery of potential therapeutic avenues. Here, we demonstrate that the RNA-binding protein ELAVL3 is specifically upregulated in neuroendocrine prostate cancer and that overexpression of ELAVL3 alone is …
Uncovering the oncogenic mechanisms could lead to the discovery of potential therapeutic avenues. Here, we demonstrate that the RNA-binding …
Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.
Diaz-Garcia S, Ko VI, Vazquez-Sanchez S, Chia R, Arogundade OA, Rodriguez MJ, Traynor BJ, Cleveland D, Ravits J. Diaz-Garcia S, et al. Acta Neuropathol. 2021 Dec;142(6):985-1001. doi: 10.1007/s00401-021-02374-4. Epub 2021 Oct 7. Acta Neuropathol. 2021. PMID: 34618203 Free PMC article.
Strikingly, ELAVL3 abnormalities were more frequent than TDP-43 abnormalities and occurred in motor neurons still with normal nuclear TDP-43 present, but all neurons with abnormal TDP-43 also had abnormal ELAVL3. In a neuron-like cell culture model using SH-SY5Y cel …
Strikingly, ELAVL3 abnormalities were more frequent than TDP-43 abnormalities and occurred in motor neurons still with normal nuclear …
Paraneoplastic neurologic syndromes.
Hirose G. Hirose G. Intern Med. 1996 Dec;35(12):925-9. doi: 10.2169/internalmedicine.35.925. Intern Med. 1996. PMID: 9030988 Free article. Review.
The presence of antibodies in serum or CSF of some patients with this disorder now accurately identifies the subgroup of the disorders related to specific neoplasms. The trend of recent studies on the pathogenesis of this disease may in the future lead to a new era to clar …
The presence of antibodies in serum or CSF of some patients with this disorder now accurately identifies the subgroup of the disorders relat …
RNA regulation went wrong in neurodevelopmental disorders: The example of Msi/Elavl RNA binding proteins.
Yano M, Hayakawa-Yano Y, Okano H. Yano M, et al. Int J Dev Neurosci. 2016 Dec;55:124-130. doi: 10.1016/j.ijdevneu.2016.01.002. Epub 2016 Jan 12. Int J Dev Neurosci. 2016. PMID: 26796049 Review.
There is substantial evidence that RNA dysregulation is critical in the pathogenesis of neurodevelopmental disorders, neurological diseases, and cancer. Several gene families encode RNA-binding proteins (RNABPs) that bind directly to RNA and orchestrate the post-transcript …
There is substantial evidence that RNA dysregulation is critical in the pathogenesis of neurodevelopmental disorders, neurological diseases, …
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.
Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly… See abstract for full author list ➔ Wang H, et al. Mol Psychiatry. 2021 Nov;26(11):6293-6304. doi: 10.1038/s41380-021-01087-0. Epub 2021 Apr 15. Mol Psychiatry. 2021. PMID: 33859359 Free PMC article.
Combined stage 1 and 2 analyses additionally identified significant gene by long sleep interactions at 10 loci including MKLN1 and RGL3/ELAVL3 previously associated with BP, and significant gene by short sleep interactions at 10 loci including C2orf43 previously associated …
Combined stage 1 and 2 analyses additionally identified significant gene by long sleep interactions at 10 loci including MKLN1 and RGL3/E …
Data on isoaspartylation of neuronal ELAVL proteins.
Pulido MA, DerHartunian MK, Sehgal P, Laird-Offringa IA. Pulido MA, et al. Data Brief. 2016 Nov 17;9:1052-1055. doi: 10.1016/j.dib.2016.11.034. eCollection 2016 Dec. Data Brief. 2016. PMID: 27924291 Free PMC article.
The data are related to the article "Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuronal protein ELAVL4" (M.A. ...Here, we present Western blot analysis data generated by using an affinity-purified polyclonal rabbit antibody …
The data are related to the article "Isoaspartylation appears to trigger small cell lung cancer-associated autoimmunity against neuro …
The neural ELAVL protein HuB enhances endogenous proto-oncogene activation.
Hatanaka T, Higashino F, Tei K, Yasuda M. Hatanaka T, et al. Biochem Biophys Res Commun. 2019 Sep 17;517(2):330-337. doi: 10.1016/j.bbrc.2019.07.089. Epub 2019 Jul 26. Biochem Biophys Res Commun. 2019. PMID: 31358321 Free article.
Conversely, the predominantly cytosolic distribution of neuron-specific human ELAV members, including HuB/ELAVL2, HuC/ELAVL3, and HuD/ELAVL4, has been reported. In the present study, we demonstrated the expression of HuB in several types of cancer cells, but express …
Conversely, the predominantly cytosolic distribution of neuron-specific human ELAV members, including HuB/ELAVL2, HuC/ELAVL3, and HuD …
Anaplastic Lymphoma Kinase Overexpression Is Associated with Aggressive Phenotypic Characteristics of Ovarian High-Grade Serous Carcinoma.
Matsumoto T, Oda Y, Hasegawa Y, Hashimura M, Oguri Y, Inoue H, Yokoi A, Tochimoto M, Nakagawa M, Jiang Z, Saegusa M. Matsumoto T, et al. Am J Pathol. 2021 Oct;191(10):1837-1850. doi: 10.1016/j.ajpath.2021.06.009. Epub 2021 Jun 29. Am J Pathol. 2021. PMID: 34214505 Free article.
Expression of the nervous system-associated gene, ELAVL3, and the corresponding protein (commonly known as HuC) was significantly increased in cells overexpressing ALK. ...Furthermore, overexpression of Sox2 or Sox3 enhanced both ALK and ELAVL3 promoter activities, …
Expression of the nervous system-associated gene, ELAVL3, and the corresponding protein (commonly known as HuC) was significantly inc …
Acute exposure to N-Ethylpentylone induces developmental toxicity and dopaminergic receptor-regulated aberrances in zebrafish larvae.
Fan E, Xu Z, Yan J, Wang F, Sun S, Zhang Y, Zheng S, Wang X, Rao Y. Fan E, et al. Toxicol Appl Pharmacol. 2021 Apr 15;417:115477. doi: 10.1016/j.taap.2021.115477. Epub 2021 Mar 3. Toxicol Appl Pharmacol. 2021. PMID: 33667508
We first observed multi-malformations in early embryos and larvae after NEP administration, together with significant deregulations of brain and heart development-associated genes (neurog1, her6, elavl3, nkx2.5, nppa, nppb, tnnt2a) at transcriptional level. Low-dosed NEP t …
We first observed multi-malformations in early embryos and larvae after NEP administration, together with significant deregulations of brain …
28 results