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Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms.
Biochim Biophys Acta. 2007 Mar;1770(3):467-77. doi: 10.1016/j.bbagen.2006.07.018. Epub 2006 Aug 2.
Biochim Biophys Acta. 2007.
PMID: 16963187
Free PMC article.
Review.
CYP51 from Trypanosoma cruzi: a phyla-specific residue in the B' helix defines substrate preferences of sterol 14alpha-demethylase.
Lepesheva GI, Zaitseva NG, Nes WD, Zhou W, Arase M, Liu J, Hill GC, Waterman MR.
Lepesheva GI, et al.
J Biol Chem. 2006 Feb 10;281(6):3577-85. doi: 10.1074/jbc.M510317200. Epub 2005 Nov 30.
J Biol Chem. 2006.
PMID: 16321980
Free article.
Item in Clipboard
Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function.
Lepesheva GI, Virus C, Waterman MR.
Lepesheva GI, et al.
Biochemistry. 2003 Aug 5;42(30):9091-101. doi: 10.1021/bi034663f.
Biochemistry. 2003.
PMID: 12885242
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Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs.
Lepesheva GI, Podust LM, Bellamine A, Waterman MR.
Lepesheva GI, et al.
J Biol Chem. 2001 Jul 27;276(30):28413-20. doi: 10.1074/jbc.M102767200. Epub 2001 May 23.
J Biol Chem. 2001.
PMID: 11373285
Free article.
Item in Clipboard
Lipopolysaccharides and cytokines downregulate the angiotensin II type 2 receptor in rat cardiac fibroblasts.
Tamura M, Chen YJ, Howard EF, Tanner M, Landon EJ, Myers PR.
Tamura M, et al.
Eur J Pharmacol. 1999 Dec 15;386(2-3):289-95. doi: 10.1016/s0014-2999(99)00755-4.
Eur J Pharmacol. 1999.
PMID: 10618481
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Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis.
Bellamine A, Mangla AT, Nes WD, Waterman MR.
Bellamine A, et al.
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8937-42. doi: 10.1073/pnas.96.16.8937.
Proc Natl Acad Sci U S A. 1999.
PMID: 10430874
Free PMC article.
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