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Year Number of Results
1995 2
1997 6
1998 2
1999 4
2000 4
2001 1
2002 3
2003 5
2004 6
2005 2
2006 16
2007 16
2008 18
2009 12
2010 17
2011 15
2012 12
2013 19
2014 17
2015 28
2016 12
2017 31
2018 15
2019 20
2020 27
2021 12
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2023 16
2024 7

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334 results

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Page 1
The Molecular Taxonomy of Primary Prostate Cancer.
Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Cell. 2015 Nov 5;163(4):1011-25. doi: 10.1016/j.cell.2015.10.025. Cell. 2015. PMID: 26544944 Free PMC article.
As part of The Cancer Genome Atlas (TCGA), we present a comprehensive molecular analysis of 333 primary prostate carcinomas. ...Our analysis reveals molecular heterogeneity among primary prostate cancers, as well as potentially actionable molecular defects....
As part of The Cancer Genome Atlas (TCGA), we present a comprehensive molecular analysis of 333 primary prostate carcinomas. ...Our a …
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM. Tomlins SA, et al. Science. 2005 Oct 28;310(5748):644-8. doi: 10.1126/science.1117679. Science. 2005. PMID: 16254181
We used a bioinformatics approach to discover candidate oncogenic chromosomal aberrations on the basis of outlier gene expression. Two ETS transcription factors, ERG and ETV1, were identified as outliers in prostate cancer. We identified recurrent gene fusions of th …
We used a bioinformatics approach to discover candidate oncogenic chromosomal aberrations on the basis of outlier gene expression. Two ETS t …
miR-129-5p inhibits prostate cancer proliferation via targeting ETV1.
Gao G, Xiu D, Yang B, Sun D, Wei X, Ding Y, Ma Y, Wang Z. Gao G, et al. Onco Targets Ther. 2019 May 9;12:3531-3544. doi: 10.2147/OTT.S183435. eCollection 2019. Onco Targets Ther. 2019. PMID: 31190859 Free PMC article.
In addition, elevation of miR-129-5p decreased ETV1 expression in prostate cancer cells while downregulation of miR-129-5p increased ETV1 expression in RWPE-1. Mechanistically, ETV1 is confirmed a direct target of miR-129-5p in prostate cancer c …
In addition, elevation of miR-129-5p decreased ETV1 expression in prostate cancer cells while downregulation of miR-129-5p inc …
Development and characterization of an ETV1 rabbit monoclonal antibody for the immunohistochemical detection of ETV1 expression in cancer tissue specimens.
Schafer C, Young D, Singh H, Jayakrishnan R, Banerjee S, Song Y, Dobi A, Petrovics G, Srivastava S, Srivastava S, Sesterhenn IA, Chesnut GT, Tan SH. Schafer C, et al. J Immunol Methods. 2023 Jul;518:113493. doi: 10.1016/j.jim.2023.113493. Epub 2023 May 16. J Immunol Methods. 2023. PMID: 37196930 Free article.
BACKGROUND: Aberrant ETV1 overexpression arising from gene rearrangements or mutations occur frequently in prostate cancer, round cell sarcomas, gastrointestinal stromal tumors, gliomas, and other malignancies. ...SPRi measurements revealed an equilibrium dissociati …
BACKGROUND: Aberrant ETV1 overexpression arising from gene rearrangements or mutations occur frequently in prostate cancer, ro …
HGF-mediated elevation of ETV1 facilitates hepatocellular carcinoma metastasis through upregulating PTK2 and c-MET.
Zhang T, Wang Y, Xie M, Ji X, Luo X, Chen X, Zhang B, Liu D, Feng Y, Sun M, Huang W, Xia L. Zhang T, et al. J Exp Clin Cancer Res. 2022 Sep 16;41(1):275. doi: 10.1186/s13046-022-02475-2. J Exp Clin Cancer Res. 2022. PMID: 36109787 Free PMC article.
Notably, in two independent cohorts, patients with positive coexpression of ETV1/PTK2 or ETV1/c-MET had worse prognosis. Furthermore, the combination of PTK2 inhibitor defactinib and c-MET inhibitor capmatinib significantly suppressed HCC metastasis induced by ET …
Notably, in two independent cohorts, patients with positive coexpression of ETV1/PTK2 or ETV1/c-MET had worse prognosis. Furth …
ETS factors in prostate cancer.
Qian C, Li D, Chen Y. Qian C, et al. Cancer Lett. 2022 Apr 1;530:181-189. doi: 10.1016/j.canlet.2022.01.009. Epub 2022 Jan 14. Cancer Lett. 2022. PMID: 35033589 Free PMC article. Review.
The ETS family of proteins consists of 28 transcription factors, many of which play critical roles in both normal tissue development and homeostasis and have been implicated in development and progression of a variety of cancers. In prostate cancer, gene fusion and …
The ETS family of proteins consists of 28 transcription factors, many of which play critical roles in both normal tissue development and hom …
ETV1 Positively Correlated With Immune Infiltration and Poor Clinical Prognosis in Colorectal Cancer.
Shen X, Zhou C, Feng H, Li J, Xia T, Cheng X, Zhao R, Zou D. Shen X, et al. Front Immunol. 2022 Jul 4;13:939806. doi: 10.3389/fimmu.2022.939806. eCollection 2022. Front Immunol. 2022. PMID: 35860243 Free PMC article.
Furthermore, ETV1 tends to be associated with immune infiltration of CRC, especially with cancer-associated fibroblasts and M2 macrophages. ...Moreover, ETV1 was significantly associated with the infiltration of cancer-associated fibroblasts and M2 mac …
Furthermore, ETV1 tends to be associated with immune infiltration of CRC, especially with cancer-associated fibroblasts and M2 …
Sumoylation of transcription factor ETV1 modulates its oncogenic potential in prostate cancer.
Oh S, Shin S, Janknecht R. Oh S, et al. Int J Clin Exp Pathol. 2021 Jul 15;14(7):795-810. eCollection 2021. Int J Clin Exp Pathol. 2021. PMID: 34367411 Free PMC article.
In stark contrast, sumoylation-deficient ETV1 was repressed in its ability to stimulate the MMP1 promoter and to cooperate with a histone demethylase, JmjC domain-containing 2A (JMJD2A), in LNCaP prostate cancer cells. ...Notably, SUMO pathway components SUMO1, ubiq …
In stark contrast, sumoylation-deficient ETV1 was repressed in its ability to stimulate the MMP1 promoter and to cooperate with a his …
What is New in Gastrointestinal Stromal Tumor?
Schaefer IM, Mariño-Enríquez A, Fletcher JA. Schaefer IM, et al. Adv Anat Pathol. 2017 Sep;24(5):259-267. doi: 10.1097/PAP.0000000000000158. Adv Anat Pathol. 2017. PMID: 28632504 Free PMC article. Review.
Recent advances extend our understanding of GIST biology beyond that of the oncogenic KIT/PDGFRA tyrosine kinases and beyond mechanisms of KIT/PDGFRA-inhibitor treatment response and resistance. These advances have characterized ETV1 as an essential interstitial cell of Ca …
Recent advances extend our understanding of GIST biology beyond that of the oncogenic KIT/PDGFRA tyrosine kinases and beyond mechanisms of K …
Novel ETV1 mutation in small cell lung cancer transformation resistant to EGFR tyrosine kinase inhibitors.
Zhou Y, Bai H, Xia J, Xu WY, Cheng L, Xiong L. Zhou Y, et al. Ann Transl Med. 2021 Jul;9(14):1150. doi: 10.21037/atm-21-2625. Ann Transl Med. 2021. PMID: 34430591 Free PMC article.
ETV1 p.E462Q and p.P159S mutations were also resistant to gefitinib and osimertinib after introduction into H358 cells. CONCLUSIONS: Novel ETV1 p.E462Q and p.P159S mutations were found in the SCLC tissues of TKIs-resistant LUAD patients, providing a new understandin …
ETV1 p.E462Q and p.P159S mutations were also resistant to gefitinib and osimertinib after introduction into H358 cells. CONCLUSIONS: …
334 results