Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 2
1997 3
1998 2
1999 1
2000 3
2001 1
2002 2
2003 6
2004 5
2005 6
2006 10
2007 10
2008 9
2009 3
2010 8
2011 16
2012 11
2013 9
2014 10
2015 19
2016 13
2017 24
2018 22
2019 25
2020 26
2021 33
2022 34
2023 28
2024 12

Text availability

Article attribute

Article type

Publication date

Search Results

321 results

Results by year

Filters applied: . Clear all
Page 1
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Zhang Q, Liu S, Wang H, Xiao K, Lu J, Chen S, Huang M, Xie R, Lin T, Chen X. Zhang Q, et al. Adv Sci (Weinh). 2023 Apr;10(11):e2205613. doi: 10.1002/advs.202205613. Epub 2023 Jan 20. Adv Sci (Weinh). 2023. PMID: 36670069 Free PMC article.
Moreover, phosphorylation of ETV4 at tyrosine 392 by tyrosine kinase PTK6 increases nuclear translocation of ETV4 and is essential for its function in BCa. Overall, the findings reveal a novel mechanism of how tumor cells regulate TANs-induced lymphangiogenesis and …
Moreover, phosphorylation of ETV4 at tyrosine 392 by tyrosine kinase PTK6 increases nuclear translocation of ETV4 and is essen …
FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2.
Xie M, Lin Z, Ji X, Luo X, Zhang Z, Sun M, Chen X, Zhang B, Liang H, Liu D, Feng Y, Wang Y, Li Y, Liu B, Huang W, Xia L. Xie M, et al. J Hepatol. 2023 Jul;79(1):109-125. doi: 10.1016/j.jhep.2023.02.036. Epub 2023 Mar 11. J Hepatol. 2023. PMID: 36907560
This study was designed to investigate the role of E-twenty-six-specific sequence variant 4 (ETV4) in promoting HCC metastasis and to explore a new combination therapy strategy for ETV4-mediated HCC metastasis. ...Additionally, ETV4 upregulated FGFR4 expressi …
This study was designed to investigate the role of E-twenty-six-specific sequence variant 4 (ETV4) in promoting HCC metastasis and to …
ETV4 promotes the progression of gastric cancer through regulating KDM5D.
Cai LS, Chen QX, Fang SY, Lian MQ, Lian MJ, Cai MZ. Cai LS, et al. Eur Rev Med Pharmacol Sci. 2020 Mar;24(5):2442-2451. doi: 10.26355/eurrev_202003_20511. Eur Rev Med Pharmacol Sci. 2020. PMID: 32196595 Free article.
OBJECTIVE: This study was aimed to investigate the expression characteristics of ETS variant 4 (ETV4) in gastric cancer (GCa), and to further explore whether it promotes the development of GCa by regulating KDM5D. ...Similarly, the metastasis ability of GCa cells in …
OBJECTIVE: This study was aimed to investigate the expression characteristics of ETS variant 4 (ETV4) in gastric cancer (GCa), …
ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.
Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z. Zhu T, et al. Cell Death Discov. 2021 May 29;7(1):126. doi: 10.1038/s41420-021-00508-x. Cell Death Discov. 2021. PMID: 34052833 Free PMC article.
In human breast cancer and hepatocellular carcinoma tissues, ETV4 expression is positively correlated with glycolytic signaling. ...Mechanistically, on the one hand, we find that ETV4 may enhance glycolysis activity to facilitate breast cancer stemness …
In human breast cancer and hepatocellular carcinoma tissues, ETV4 expression is positively correlated with glycolytic signalin …
USP15 negatively regulates lung cancer progression through the TRAF6-BECN1 signaling axis for autophagy induction.
Kim MJ, Min Y, Jeong SK, Son J, Kim JY, Lee JS, Kim DH, Lee JS, Chun E, Lee KY. Kim MJ, et al. Cell Death Dis. 2022 Apr 14;13(4):348. doi: 10.1038/s41419-022-04808-7. Cell Death Dis. 2022. PMID: 35422093 Free PMC article.
Herein, we provide novel molecular and cellular mechanisms involved in the negative effect of ubiquitin-specific peptidase 15 (USP15) on lung cancer progression. Clinical data of the TCGA and primary non-small cell lung cancer (NSCLC) patients (n = 41) revealed that …
Herein, we provide novel molecular and cellular mechanisms involved in the negative effect of ubiquitin-specific peptidase 15 (USP15) on lun …
Oncogenic role and drug sensitivity of ETV4 in human tumors: a pan-cancer analysis.
Zhang R, Peng Y, Gao Z, Qian J, Yang K, Wang X, Lu W, Zhu Y, Qiu D, Jin T, Wang G, He J, Liu N. Zhang R, et al. Front Oncol. 2023 May 2;13:1121258. doi: 10.3389/fonc.2023.1121258. eCollection 2023. Front Oncol. 2023. PMID: 37205199 Free PMC article.
BACKGROUND: Increasing evidence supports a relationship between E twenty-six variant transcription factor 4 (ETV4) and several cancers, but no pan-cancer analysis has been reported. METHODS: The present study surveyed the effects of ETV4 on cancer …
BACKGROUND: Increasing evidence supports a relationship between E twenty-six variant transcription factor 4 (ETV4) and several can …
Transcription factor ETV4 promotes the development of hepatocellular carcinoma by driving hepatic TNF-alpha signaling.
Qi D, Lu M, Xu P, Yao X, Chen Y, Gan L, Li Y, Cui Y, Tong X, Liu S, Zhao J, Liu N, Ye X. Qi D, et al. Cancer Commun (Lond). 2023 Dec;43(12):1354-1372. doi: 10.1002/cac2.12482. Epub 2023 Sep 5. Cancer Commun (Lond). 2023. PMID: 37670477 Free PMC article.
RNA sequencing and luciferase reporter assays were performed to identify the target genes of ETV4. Hepatocyte-specific ETV4-knockout (ETV4(fl/fl, alb-cre) ) and transgenic (ETV4(Hep-TG) ) mice and diethylnitrosamine-carbon tetrachloride (DEN-CCL(4) ) t …
RNA sequencing and luciferase reporter assays were performed to identify the target genes of ETV4. Hepatocyte-specific ETV4-kn …
ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells.
Rodriguez AC, Vahrenkamp JM, Berrett KC, Clark KA, Guillen KP, Scherer SD, Yang CH, Welm BE, Janát-Amsbury MM, Graves BJ, Gertz J. Rodriguez AC, et al. Cancer Res. 2020 Mar 15;80(6):1234-1245. doi: 10.1158/0008-5472.CAN-19-1382. Epub 2020 Feb 11. Cancer Res. 2020. PMID: 32046982 Free PMC article.
We previously identified ETV4 as a candidate factor controlling ER genomic binding in endometrial cancer cells, and here we explore the functional importance of ETV4. ...These results show that ETV4 plays an important role in estrogen signaling in endo …
We previously identified ETV4 as a candidate factor controlling ER genomic binding in endometrial cancer cells, and here we ex …
ETV4 facilitates proliferation, migration, and invasion of liver cancer by mediating TGF-beta signal transduction through activation of B3GNT3.
Zhou Z, Wu B, Chen J, Shen Y, Wang J, Chen X, Fei F, Li L. Zhou Z, et al. Genes Genomics. 2023 Nov;45(11):1433-1443. doi: 10.1007/s13258-023-01428-z. Epub 2023 Jul 31. Genes Genomics. 2023. PMID: 37523127
BACKGROUND: Metastasis of liver cancer (LC) is the main cause of its high mortality. ETV4 is a critical regulatory factor in promoting LC progression, but the mechanism that ETV4 impacts LC proliferation, migration, and invasion is poorly understood. ...Knock …
BACKGROUND: Metastasis of liver cancer (LC) is the main cause of its high mortality. ETV4 is a critical regulatory factor in p …
ETV4 mediates dosage-dependent prostate tumor initiation and cooperates with p53 loss to generate prostate cancer.
Li D, Zhan Y, Wang N, Tang F, Lee CJ, Bayshtok G, Moore AR, Wong EWP, Pachai MR, Xie Y, Sher J, Zhao JL, Khudoynazarova M, Gopalan A, Chan J, Khurana E, Shepherd P, Navone NM, Chi P, Chen Y. Li D, et al. Sci Adv. 2023 Apr 5;9(14):eadc9446. doi: 10.1126/sciadv.adc9446. Epub 2023 Apr 5. Sci Adv. 2023. PMID: 37018402 Free PMC article.
Lower-level expression of ETV4 caused mild luminal cell expansion without histologic abnormalities, and higher-level expression of stabilized ETV4 caused prostatic intraepithelial neoplasia (mPIN) with 100% penetrance within 1 week. Tumor progression was limited by …
Lower-level expression of ETV4 caused mild luminal cell expansion without histologic abnormalities, and higher-level expression of st …
321 results