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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2004 1
2005 1
2006 1
2008 3
2009 2
2010 4
2011 2
2012 2
2013 2
2014 1
2015 4
2016 1
2017 1
2018 3
2019 3
2020 2
2023 1
2024 2

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35 results

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Page 1
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity.
Ishikawa H, Ma Z, Barber GN. Ishikawa H, et al. Nature. 2009 Oct 8;461(7265):788-92. doi: 10.1038/nature08476. Epub 2009 Sep 23. Nature. 2009. PMID: 19776740 Free PMC article.
In the presence of intracellular DNA, STING relocalized with TANK-binding kinase 1 (TBK1) from the endoplasmic reticulum to perinuclear vesicles containing the exocyst component Sec5 (also known as EXOC2). Collectively, our studies indicate that STING is essential for host …
In the presence of intracellular DNA, STING relocalized with TANK-binding kinase 1 (TBK1) from the endoplasmic reticulum to perinuclear vesi …
Mutations in the exocyst component EXOC2 cause severe defects in human brain development.
Van Bergen NJ, Ahmed SM, Collins F, Cowley M, Vetro A, Dale RC, Hock DH, de Caestecker C, Menezes M, Massey S, Ho G, Pisano T, Glover S, Gusman J, Stroud DA, Dinger M, Guerrini R, Macara IG, Christodoulou J. Van Bergen NJ, et al. J Exp Med. 2020 Oct 5;217(10):e20192040. doi: 10.1084/jem.20192040. J Exp Med. 2020. PMID: 32639540 Free PMC article.
Family 1 had two offspring with a homozygous truncating variant in EXOC2 that leads to nonsense-mediated decay of EXOC2 transcript, a severe reduction in exocytosis and vesicle fusion, and undetectable levels of EXOC2 protein. ...The discovery of mutations th …
Family 1 had two offspring with a homozygous truncating variant in EXOC2 that leads to nonsense-mediated decay of EXOC2 transc …
Role of selected genetic variants in lung cancer risk in African Americans.
Spitz MR, Amos CI, Land S, Wu X, Dong Q, Wenzlaff AS, Schwartz AG. Spitz MR, et al. J Thorac Oncol. 2013 Apr;8(4):391-7. doi: 10.1097/JTO.0b013e318283da29. J Thorac Oncol. 2013. PMID: 23454887 Free PMC article.
INTRODUCTION: Black/white disparities in lung cancer incidence and mortality mandate an evaluation of underlying biological differences. We have previously shown higher risks of lung cancer associated with prior emphysema in African American compared with white pati …
INTRODUCTION: Black/white disparities in lung cancer incidence and mortality mandate an evaluation of underlying biological differenc …
Genome-wide association study of circulating folate one-carbon metabolites.
Wang J, Asante I, Baron JA, Figueiredo JC, Haile R, Joan Levine A, Newcomb PA, Templeton AS, Schumacher FR, Louie SG, Casey G, Conti DV. Wang J, et al. Genet Epidemiol. 2019 Dec;43(8):1030-1045. doi: 10.1002/gepi.22249. Epub 2019 Sep 10. Genet Epidemiol. 2019. PMID: 31502714 Free PMC article.
Experimental, observational, and clinical trials support a critical role of folate one-carbon metabolism (FOCM) in colorectal cancer (CRC) development. In this report, we focus on understanding the relationship between common genetic variants and metabolites of FOCM. ...Fu …
Experimental, observational, and clinical trials support a critical role of folate one-carbon metabolism (FOCM) in colorectal cancer …
Integrating understanding of epidemiology and genomics in B-cell non-Hodgkin lymphoma as a pathway to novel management strategies.
Glass S, Phan A, Williams JN, Flowers CR, Koff JL. Glass S, et al. Discov Med. 2016 Mar;21(115):181-8. Discov Med. 2016. PMID: 27115168 Free PMC article. Review.
Non-Hodgkin lymphomas include a biologically and clinically heterogeneous group of cancers distinguished by genetics, histology, and treatment outcomes. ...Increased risk of diffuse large B-cell lymphoma has been associated with increased young adult body mass index, histo …
Non-Hodgkin lymphomas include a biologically and clinically heterogeneous group of cancers distinguished by genetics, histology, and …
Salmonella exploits membrane reservoirs for invasion of host cells.
Zhu H, Sydor AM, Boddy KC, Coyaud E, Laurent EMN, Au A, Tan JMJ, Yan BR, Moffat J, Muise AM, Yip CM, Grinstein S, Raught B, Brumell JH. Zhu H, et al. Nat Commun. 2024 Apr 10;15(1):3120. doi: 10.1038/s41467-024-47183-x. Nat Commun. 2024. PMID: 38600106 Free PMC article.
Under normal growth conditions, membrane reservoirs contribute to PM homeostasis and are preloaded with the exocyst subunit EXOC2. During Salmonella invasion, the bacterial effectors SipC, SopE2, and SopB recruit exocyst subunits from membrane reservoirs and other cellular …
Under normal growth conditions, membrane reservoirs contribute to PM homeostasis and are preloaded with the exocyst subunit EXOC2. Du …
A closer look at evolution: Variants (SNPs) of genes involved in skin pigmentation, including EXOC2, TYR, TYRP1, and DCT, are associated with 25(OH)D serum concentration.
Saternus R, Pilz S, Gräber S, Kleber M, März W, Vogt T, Reichrath J. Saternus R, et al. Endocrinology. 2015 Jan;156(1):39-47. doi: 10.1210/en.2014-1238. Endocrinology. 2015. PMID: 25396269
Vitamin D deficiency is common in the Caucasian population and is associated with increased incidence and unfavorable outcome of many diseases, including various types of cancer, infectious, cardiovascular, and autoimmune diseases. Individual factors that predispose for a …
Vitamin D deficiency is common in the Caucasian population and is associated with increased incidence and unfavorable outcome of many diseas …
RalGPS2 is involved in tunneling nanotubes formation in 5637 bladder cancer cells.
D'Aloia A, Berruti G, Costa B, Schiller C, Ambrosini R, Pastori V, Martegani E, Ceriani M. D'Aloia A, et al. Exp Cell Res. 2018 Jan 15;362(2):349-361. doi: 10.1016/j.yexcr.2017.11.036. Epub 2017 Dec 6. Exp Cell Res. 2018. PMID: 29208460
Up to now, few data have been published regarding RalGPS2 role in cancer cells, and its involvement in bladder cancer is yet to be established. In this paper we demonstrated that RalGPS2 is expressed in urothelial carcinoma-derived 5637 cancer cells and is es …
Up to now, few data have been published regarding RalGPS2 role in cancer cells, and its involvement in bladder cancer is yet t …
The role of novel fusion genes in human GIST cell lines derived from imatinib-resistant GIST patients: A therapeutic potential of fusion gene.
Cho WC, Shin YK, Na YS, Ryu MH, Ku JL, Kang YK. Cho WC, et al. Biochem Biophys Res Commun. 2020 Aug 27;529(3):699-706. doi: 10.1016/j.bbrc.2020.05.174. Epub 2020 Jul 18. Biochem Biophys Res Commun. 2020. PMID: 32736695 Free article.
Three different fusion gene analysis methods were used to find candidate fusion genes, including EIF3K-ACTN4, SYNCRIP-SNX14 and EXOC2-AK7. A novel interchromosomal fusion gene of the candidates, especially EXOC2-AK7, was confirmed in both tissue and cell line. ...In …
Three different fusion gene analysis methods were used to find candidate fusion genes, including EIF3K-ACTN4, SYNCRIP-SNX14 and EXOC2 …
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.
Cerhan JR, Berndt SI, Vijai J, Ghesquières H, McKay J, Wang SS, Wang Z, Yeager M, Conde L, de Bakker PI, Nieters A, Cox D, Burdett L, Monnereau A, Flowers CR, De Roos AJ, Brooks-Wilson AR, Lan Q, Severi G, Melbye M, Gu J, Jackson RD, Kane E, Teras LR, Purdue MP, Vajdic CM, Spinelli JJ, Giles GG, Albanes D, Kelly RS, Zucca M, Bertrand KA, Zeleniuch-Jacquotte A, Lawrence C, Hutchinson A, Zhi D, Habermann TM, Link BK, Novak AJ, Dogan A, Asmann YW, Liebow M, Thompson CA, Ansell SM, Witzig TE, Weiner GJ, Veron AS, Zelenika D, Tilly H, Haioun C, Molina TJ, Hjalgrim H, Glimelius B, Adami HO, Bracci PM, Riby J, Smith MT, Holly EA, Cozen W, Hartge P, Morton LM, Severson RK, Tinker LF, North KE, Becker N, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, Lightfoot T, Crouch S, Smith A, Roman E, Diver WR, Offit K, Zelenetz A, Klein RJ, Villano DJ, Zheng T, Zhang Y, Holford TR, Kricker A, Turner J, Southey MC, Clavel J, Virtamo J, Weinstein S, Riboli E, Vineis P, Kaaks R, Trichopoulos D, Vermeulen RC, Boeing H, Tjonneland A, Angelucci E, Di Lollo S, Rais M, Birmann BM, Laden F, Giovannucci E, Kraft P, Huang J, Ma B, Ye Y, Chiu BC, Sampson J, Liang L, Park JH, Chung CC, We… See abstract for full author list ➔ Cerhan JR, et al. Nat Genet. 2014 Nov;46(11):1233-8. doi: 10.1038/ng.3105. Epub 2014 Sep 28. Nat Genet. 2014. PMID: 25261932 Free PMC article.
In our multi-stage analysis, five independent SNPs in four loci achieved genome-wide significance marked by rs116446171 at 6p25.3 (EXOC2; P = 2.33 10(-21)), rs2523607 at 6p21.33 (HLA-B; P = 2.40 10(-10)), rs79480871 at 2p23.3 (NCOA1; P = 4.23 10(-8)) and two independent SN …
In our multi-stage analysis, five independent SNPs in four loci achieved genome-wide significance marked by rs116446171 at 6p25.3 (EXOC2 …
35 results