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Year Number of Results
1998 1
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2008 6
2009 5
2010 5
2011 6
2012 8
2013 13
2014 14
2015 15
2016 11
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2023 13
2024 10

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186 results

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Page 1
EDIL3 deficiency ameliorates adverse cardiac remodelling by neutrophil extracellular traps (NET)-mediated macrophage polarization.
Wei X, Zou S, Xie Z, Wang Z, Huang N, Cen Z, Hao Y, Zhang C, Chen Z, Zhao F, Hu Z, Teng X, Gui Y, Liu X, Zheng H, Zhou H, Chen S, Cheng J, Zeng F, Zhou Y, Wu W, Hu J, Wei Y, Cui K, Li J. Wei X, et al. Cardiovasc Res. 2022 Jul 20;118(9):2179-2195. doi: 10.1093/cvr/cvab269. Cardiovasc Res. 2022. PMID: 34375400
Either insufficient or excessive inflammation impairs cardiac healing. As an endogenous inhibitor of neutrophil adhesion, EDIL3 plays a crucial role in inflammatory regulation. However, the role of EDIL3 in MI remains obscure. We aimed to define the role of EDIL3 …
Either insufficient or excessive inflammation impairs cardiac healing. As an endogenous inhibitor of neutrophil adhesion, EDIL3 plays …
EDIL3 as an Angiogenic Target of Immune Exclusion Following Checkpoint Blockade.
Tabasum S, Thapa D, Giobbie-Hurder A, Weirather JL, Campisi M, Schol PJ, Li X, Li J, Yoon CH, Manos MP, Barbie DA, Hodi FS. Tabasum S, et al. Cancer Immunol Res. 2023 Nov 1;11(11):1493-1507. doi: 10.1158/2326-6066.CIR-23-0171. Cancer Immunol Res. 2023. PMID: 37728484 Free PMC article.
Our in vitro studies validated EDIL3 overexpression and TGFbeta regulation in patient-derived CAFs. In pretreatment serum samples from patients, circulating levels of EDIL3 were associated with circulating levels of VEGF, and like VEGF, EDIL3 increased the an …
Our in vitro studies validated EDIL3 overexpression and TGFbeta regulation in patient-derived CAFs. In pretreatment serum samples fro …
EDIL3 is a potential prognostic biomarker that correlates with immune infiltrates in gastric cancer.
Ke B, Liang ZK, Li B, Wang XJ, Liu N, Liang H, Zhang RP. Ke B, et al. PeerJ. 2023 Aug 9;11:e15559. doi: 10.7717/peerj.15559. eCollection 2023. PeerJ. 2023. PMID: 37576496 Free PMC article.
However, the biological function of EDIL3 in gastric cancer (GC) is still unclear. The objective of this research was to explore the role and potential mechanism of EDIL3 in GC. ...EDIL3 could be used as a potential therapeutic target for GC....
However, the biological function of EDIL3 in gastric cancer (GC) is still unclear. The objective of this research was to explore the …
EDIL3 and VEGF Synergistically Affect Angiogenesis in Endothelial Cells.
Niu X, Li X, Feng Z, Han Q, Li J, Liu Y, Zhang K. Niu X, et al. Clin Cosmet Investig Dermatol. 2023 May 18;16:1269-1277. doi: 10.2147/CCID.S411253. eCollection 2023. Clin Cosmet Investig Dermatol. 2023. PMID: 37223216 Free PMC article.
The downregulation of EDIL3 decreased VEGF and VEGFR2 expression in HUVECs. Moreover, the decreased expression of EDIL3 and VEGF reduced the growth, invasion, and tube formation abilities of HUVECs, while EDIL3 resistance to VEGF and VEGFR2 was restored by us …
The downregulation of EDIL3 decreased VEGF and VEGFR2 expression in HUVECs. Moreover, the decreased expression of EDIL3 and VE …
EDIL3 influenced the alphavbeta3-FAK/MEK/ERK axis of endothelial cells in psoriasis.
Niu X, Han Q, Li X, Li J, Liu Y, Li Y, Wu Y, Zhang K. Niu X, et al. J Cell Mol Med. 2022 Oct;26(20):5202-5212. doi: 10.1111/jcmm.17544. Epub 2022 Sep 6. J Cell Mol Med. 2022. PMID: 36065978 Free PMC article.
So, this study aimed to explore the association between EDIL3 derived from DMSCs (DMSCs-derived EDIL3) and psoriasis-associated angiogenesis. We injected recombinant EDIL3 protein to mouse model of psoriasis to confirm the roles of EDIL3 in psoriasis. …
So, this study aimed to explore the association between EDIL3 derived from DMSCs (DMSCs-derived EDIL3) and psoriasis-associate …
Psoriasis-associated angiogenesis is mediated by EDIL3.
Niu X, Han Q, Liu Y, Li J, Hou R, Li J, Zhang K. Niu X, et al. Microvasc Res. 2020 Nov;132:104056. doi: 10.1016/j.mvr.2020.104056. Epub 2020 Aug 12. Microvasc Res. 2020. PMID: 32795468
To assess the role of EDIL3 derived from DMSCs of psoriasis (P-DMSCs) in angiogenesis, in vitro, EDIL3 of DMSCs from psoriasis was silenced by interfering EDIL3. ...In vivo, EDIL3 recombinant protein was injected into IMQ cream-induced psoriasis-like s …
To assess the role of EDIL3 derived from DMSCs of psoriasis (P-DMSCs) in angiogenesis, in vitro, EDIL3 of DMSCs from psoriasis …
EDIL3 regulates gastric cancer cell migration, invasion and epithelial-mesenchymal transition via TGF-beta1/XIST/miR-137 feedback loop.
Zhang L, Peng KW, Wang B, Yang XF, Zhang ZM. Zhang L, et al. Transl Cancer Res. 2020 Oct;9(10):6313-6330. doi: 10.21037/tcr-19-2967b. Transl Cancer Res. 2020. PMID: 35117240 Free PMC article.
EDIL3 knockdown suppressed migration, invasion and EMT, which were reversed by XIST. Overexpression of miR-137 inhibited proliferation, migration, invasion and EMT, which were reversed by EDIL3 overexpression. CONCLUSIONS: EDIL3 regulates gastric cancer cell …
EDIL3 knockdown suppressed migration, invasion and EMT, which were reversed by XIST. Overexpression of miR-137 inhibited proliferatio …
EDIL3 promotes epithelial-mesenchymal transition and paclitaxel resistance through its interaction with integrin alpha(V)beta(3) in cancer cells.
Gasca J, Flores ML, Jiménez-Guerrero R, Sáez ME, Barragán I, Ruíz-Borrego M, Tortolero M, Romero F, Sáez C, Japón MA. Gasca J, et al. Cell Death Discov. 2020 Sep 16;6:86. doi: 10.1038/s41420-020-00322-x. eCollection 2020. Cell Death Discov. 2020. PMID: 33014430 Free PMC article.
EDIL3 knockdown reverted EMT and sensitized cells to paclitaxel. In contrast, EDIL3 overexpression or the culture of cells in the presence of EDIL3-enriched medium induced EMT and paclitaxel resistance. ...
EDIL3 knockdown reverted EMT and sensitized cells to paclitaxel. In contrast, EDIL3 overexpression or the culture of cells in …
Identification of EDIL3 biomarkers as a biomarker and potential therapeutic target of canine mammary carcinomas based on integrated bioinformatics analysis.
Lin Z, Jiang C, Lv D, Lin D. Lin Z, et al. Vet Immunol Immunopathol. 2022 Jul;249:110432. doi: 10.1016/j.vetimm.2022.110432. Epub 2022 May 6. Vet Immunol Immunopathol. 2022. PMID: 35550248 Free article.
Moreover, we also find that low expression levels of EDIL3 are associated with advanced grade status in CMT, which indicate a negative correlation between EDIL3 and CMT development. GSEA is employed to unveil the underlying mechanism of this interesting function of …
Moreover, we also find that low expression levels of EDIL3 are associated with advanced grade status in CMT, which indicate a negativ …
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development.
Chen MF, Hu CC, Hsu YH, Lin YC, Chen KL, Ueng SWN, Chang Y. Chen MF, et al. Bone Joint Res. 2023 Dec 12;12(12):734-746. doi: 10.1302/2046-3758.1212.BJR-2023-0087.R1. Bone Joint Res. 2023. PMID: 38081212 Free PMC article.
However, the effect of EDIL3 on cartilage is still unknown. METHODS: We used human cartilage plugs (ex vivo) and mice with spontaneous OA (in vivo) to explore whether EDIL3 has a chondroprotective effect by altering OA-related indicators. RESULTS: EDIL3 prote …
However, the effect of EDIL3 on cartilage is still unknown. METHODS: We used human cartilage plugs (ex vivo) and mice with spontaneou …
186 results