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Structural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases.
FEBS J. 2015 Mar;282(6):1031-42. doi: 10.1111/febs.13200. Epub 2015 Feb 6.
FEBS J. 2015.
PMID: 25601024
Free article.
Crystal structure of the mobile metallo-β-lactamase AIM-1 from Pseudomonas aeruginosa: insights into antibiotic binding and the role of Gln157.
Leiros HK, Borra PS, Brandsdal BO, Edvardsen KS, Spencer J, Walsh TR, Samuelsen O.
Leiros HK, et al. Among authors: edvardsen ks.
Antimicrob Agents Chemother. 2012 Aug;56(8):4341-53. doi: 10.1128/AAC.00448-12. Epub 2012 Jun 4.
Antimicrob Agents Chemother. 2012.
PMID: 22664968
Free PMC article.
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His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7.
Leiros HK, Skagseth S, Edvardsen KS, Lorentzen MS, Bjerga GE, Leiros I, Samuelsen Ø.
Leiros HK, et al. Among authors: edvardsen ks.
Antimicrob Agents Chemother. 2014 Aug;58(8):4826-36. doi: 10.1128/AAC.02735-13. Epub 2014 Jun 9.
Antimicrob Agents Chemother. 2014.
PMID: 24913158
Free PMC article.
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Peripheral Blood Cells from Patients with Autoimmune Addison's Disease Poorly Respond to Interferons In Vitro, Despite Elevated Serum Levels of Interferon-Inducible Chemokines.
Edvardsen K, Bjånesøy T, Hellesen A, Breivik L, Bakke M, Husebye ES, Bratland E.
Edvardsen K, et al.
J Interferon Cytokine Res. 2015 Oct;35(10):759-70. doi: 10.1089/jir.2014.0171. Epub 2015 May 15.
J Interferon Cytokine Res. 2015.
PMID: 25978633
Free PMC article.
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Analysis of cellular and humoral immune responses against cytomegalovirus in patients with autoimmune Addison's disease.
Edvardsen K, Hellesen A, Husebye ES, Bratland E.
Edvardsen K, et al.
J Transl Med. 2016 Mar 9;14:68. doi: 10.1186/s12967-016-0822-z.
J Transl Med. 2016.
PMID: 26956521
Free PMC article.
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The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease.
Hellesen A, Edvardsen K, Breivik L, Husebye ES, Bratland E.
Hellesen A, et al.
Clin Exp Immunol. 2014 Jun;176(3):351-62. doi: 10.1111/cei.12291.
Clin Exp Immunol. 2014.
PMID: 24666275
Free PMC article.
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21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison's Disease Are Restricted by HLA-A2 and HLA-C7 Molecules.
Hellesen A, Aslaksen S, Breivik L, Røyrvik EC, Bruserud Ø, Edvardsen K, Brokstad KA, Wolff ASB, Husebye ES, Bratland E.
Hellesen A, et al.
Front Immunol. 2021 Oct 14;12:742848. doi: 10.3389/fimmu.2021.742848. eCollection 2021.
Front Immunol. 2021.
PMID: 34721410
Free PMC article.
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