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Effects of thiamine deficiency on the biosynthesis of insulin in rats.
Rathanaswami P, Sundaresan R. Rathanaswami P, et al. Biochem Int. 1991 Aug;24(6):1057-62. Biochem Int. 1991. PMID: 1781784
The effect of thiamine deficiency on insulin biosynthesis was studied. In thiamine deficient rats the total pancreatic protein content was not altered when compared to control rats whereas the pancreatic insulin conte …
The effect of thiamine deficiency on insulin biosynthesis was studied. In thiamine deficient ra
Effects of thiamine deficiency on the secretion of insulin and the metabolism of glucose in isolated rat pancreatic islets.
Rathanaswami P, Pourany A, Sundaresan R. Rathanaswami P, et al. Biochem Int. 1991 Oct;25(3):577-83. Biochem Int. 1991. PMID: 1805801
Isolated pancreatic islets from thiamine deficient rats secrete less insulin. The secretion of insulin in response to glucose and tolbutamide is also decreased in these islets. ...The results suggest that in thiamine deficiency the ins
Isolated pancreatic islets from thiamine deficient rats secrete less insulin. The secretion of insulin in respon …
Effect of inulin and oligofructose enrichment of the diet on rats suffering thiamine deficiency.
Dębski B, Kurył T, Gralak MA, Pierzynowska J, Drywień M. Dębski B, et al. J Anim Physiol Anim Nutr (Berl). 2011 Jun;95(3):335-42. doi: 10.1111/j.1439-0396.2010.01059.x. Epub 2010 Sep 29. J Anim Physiol Anim Nutr (Berl). 2011. PMID: 20880290
Prolongation of experiment cause lowering of uptake of this sugar. In rats, energy production from fatty acids (FA) seems to be less sensitive to thiamine deficiency than glycolysis. After 30 days of feeding, utilization of FA in rats was depressed to …
Prolongation of experiment cause lowering of uptake of this sugar. In rats, energy production from fatty acids (FA) seems to be less …
Effects of insulin secretagogues on the secretion of insulin during thiamine deficiency.
Rathanaswami P, Sundaresan R. Rathanaswami P, et al. Biochem Int. 1988 Sep;17(3):523-8. Biochem Int. 1988. PMID: 3060121
The fasting blood glucose was increased and the serum insulin was decreased in thiamine deficiency. Leucine and arginine did not enhance insulin secretion in thiamine deficient animals. Tolbutamide induces the insulin secretion minimally …
The fasting blood glucose was increased and the serum insulin was decreased in thiamine deficiency. Leucine and arginin …
Thiamine pyrophosphate improved vascular complications of diabetes in rats with type 2 diabetes by reducing glycation, oxidative stress, and inflammation markers.
Mahdavifard S, Nakhjavani M. Mahdavifard S, et al. Med J Islam Repub Iran. 2020 May 13;34:47. doi: 10.34171/mjiri.34.47. eCollection 2020. Med J Islam Repub Iran. 2020. PMID: 32884922 Free PMC article.
Background: Thiamine deficiency contributes to hyperglycemia and diabetes complications. Thus, in this study, the effect of thiamine pyrophosphate (TPP) on the in vivo and in vitro formation of glycation, oxidative stress, and inflammatory markers (the …
Background: Thiamine deficiency contributes to hyperglycemia and diabetes complications. Thus, in this study, the effect
Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency.
Tanaka T, Sohmiya K, Kono T, Terasaki F, Horie R, Ohkaru Y, Muramatsu M, Takai S, Miyazaki M, Kitaura Y. Tanaka T, et al. Mol Cell Biochem. 2007 May;299(1-2):23-35. doi: 10.1007/s11010-005-9032-3. Mol Cell Biochem. 2007. PMID: 16645728
We hypothesized that (1) the abundant intracellular glucose is not oxidized proportionally and (2) the correction of the uncoupling of glucose oxidation to its cellular entry might be effective against the pathophysiology of CD36-defective SHR. Therefore, we attempted to a …
We hypothesized that (1) the abundant intracellular glucose is not oxidized proportionally and (2) the correction of the uncoupling of gluco …
Modulation of A and B cell functions by tolbutamide and arginine in the pancreas of thiamine-deficient rats.
Rathanaswami P, Sundaresan R. Rathanaswami P, et al. Biochem Int. 1989 Oct;19(4):793-802. Biochem Int. 1989. PMID: 2695088
In thiamine deficiency, insulin secretion and glucose tolerance were impaired during glucose ingestion. ...The fasting plasma glucagon level was high in thiamine deficiency. Tolbutamide increased the plasma glucagon in control rats, but d …
In thiamine deficiency, insulin secretion and glucose tolerance were impaired during glucose ingestion. ...The fasting …
Role of thiamine metabolism in the central nervous system. II. Effects of various agents on thiamine triphosphatase activity in rat brain.
Iwata H, Baba A, Matsuda T, Terashita Z, Ishii K. Iwata H, et al. Jpn J Pharmacol. 1974 Dec;24(6):825-9. doi: 10.1254/jjp.24.825. Jpn J Pharmacol. 1974. PMID: 4377016 Free article.
The effects of various agents on the activity of brain thiamine triphosphatase (TTPase) in vivo and in vitro were studied. Thiamine deficiency caused a significant increase in soluble TTPase activity and a decrease in membrane-associated TTPase activit …
The effects of various agents on the activity of brain thiamine triphosphatase (TTPase) in vivo and in vitro were studied. …
High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats.
Karachalias N, Babaei-Jadidi R, Kupich C, Ahmed N, Thornalley PJ. Karachalias N, et al. Ann N Y Acad Sci. 2005 Jun;1043:777-83. doi: 10.1196/annals.1333.090. Ann N Y Acad Sci. 2005. PMID: 16037305
The streptozotocin-induced (STZ) diabetic rat experimental model of diabetes on insulin maintenance therapy exhibits dyslipidemia, mild thiamine deficiency, and increased plasma protein advanced glycation end products (AGEs). The reversal of thiamine
The streptozotocin-induced (STZ) diabetic rat experimental model of diabetes on insulin maintenance therapy exhibits dyslipidemia, mi …