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Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients - A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial.
Simon P, Petroff D, Dorn C, Ehmann L, Kloft C, Prettin C, Dietrich A, Zeitlinger M, Kees F, Wrigge H. Simon P, et al. Among authors: ehmann l. Contemp Clin Trials Commun. 2019 May 10;15:100375. doi: 10.1016/j.conctc.2019.100375. eCollection 2019 Sep. Contemp Clin Trials Commun. 2019. PMID: 31193565 Free PMC article.
Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Simon P, Busse D, Petroff D, Dorn C, Ehmann L, Hochstädt S, Girrbach F, Dietrich A, Zeitlinger M, Kees F, Kloft C, Wrigge H. Simon P, et al. Among authors: ehmann l. J Clin Med. 2020 Apr 9;9(4):1067. doi: 10.3390/jcm9041067. J Clin Med. 2020. PMID: 32283731 Free PMC article.
Elimination of Doripenem during Dialysis and Pharmacokinetic Evaluation of Posthemodialysis Dosing for Patients Undergoing Intermittent Renal Replacement Therapy.
Vossen MG, Ehmann L, Pferschy S, Maier-Salamon A, Haidinger M, Weiser C, Wenisch JM, Saria K, Kajahn C, Jilch S, Lemmerer R, Bécède M, Zeitlinger M, Kloft C, Jäger W, Thalhammer F. Vossen MG, et al. Among authors: ehmann l. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02430-17. doi: 10.1128/AAC.02430-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29530855 Free PMC article. Clinical Trial.
LogD-based modelling and ΔlogD as a proxy for pH-dependent action of ionizable chemicals reveal the relevance of both neutral and ionic species for fish embryotoxicity and possess great potential for practical application in the regulation of chemicals.
Köhler HR, Gräff T, Schweizer M, Blumhardt J, Burkhardt J, Ehmann L, Hebel J, Heid C, Kundy L, Kuttler J, Malusova M, Moroff FM, Schlösinger AF, Schulze-Berge P, Panagopoulou EI, Damalas DE, Thomaidis NS, Triebskorn R, Maletzki D, Kühnen U, von der Ohe PC. Köhler HR, et al. Among authors: ehmann l. Water Res. 2023 May 15;235:119864. doi: 10.1016/j.watres.2023.119864. Epub 2023 Mar 14. Water Res. 2023. PMID: 36944304 Free article.
27 results