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A review on the impact of P-glycoprotein on the penetration of drugs into the brain. Focus on psychotropic drugs.
Eur Neuropsychopharmacol. 2008 Mar;18(3):157-69. doi: 10.1016/j.euroneuro.2007.06.003. Epub 2007 Aug 1.
Eur Neuropsychopharmacol. 2008.
PMID: 17683917
Review.
A review on the relation between the brain-serum concentration ratio of drugs and the influence of P-glycoprotein.
Ejsing TB, Morling N, Linnet K.
Ejsing TB, et al.
Drug Metabol Drug Interact. 2007;22(2-3):113-29. doi: 10.1515/dmdi.2007.22.2-3.113.
Drug Metabol Drug Interact. 2007.
PMID: 17708063
Review.
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Influence of P-glycoprotein inhibition on the distribution of the tricyclic antidepressant nortriptyline over the blood-brain barrier.
Ejsing TB, Linnet K.
Ejsing TB, et al.
Hum Psychopharmacol. 2005 Mar;20(2):149-53. doi: 10.1002/hup.667.
Hum Psychopharmacol. 2005.
PMID: 15624117
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The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites.
Ejsing TB, Hasselstrøm J, Linnet K.
Ejsing TB, et al.
Drug Metabol Drug Interact. 2006;21(3-4):139-62. doi: 10.1515/dmdi.2006.21.3-4.139.
Drug Metabol Drug Interact. 2006.
PMID: 16841511
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P-glycoprotein interaction with risperidone and 9-OH-risperidone studied in vitro, in knock-out mice and in drug-drug interaction experiments.
Ejsing TB, Pedersen AD, Linnet K.
Ejsing TB, et al.
Hum Psychopharmacol. 2005 Oct;20(7):493-500. doi: 10.1002/hup.720.
Hum Psychopharmacol. 2005.
PMID: 16118767
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