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Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes.
Gastroenterology. 1998 Apr;114(4):764-74. doi: 10.1016/s0016-5085(98)70590-6.
Gastroenterology. 1998.
PMID: 9516397
The interleukin-2 receptor down-regulates the expression of cytochrome P450 in cultured rat hepatocytes.
Tinel M, Robin MA, Doostzadeh J, Maratrat M, Ballet F, Fardel N, el Kahwaji J, Beaune P, Daujat M, Labbe G, et al.
Tinel M, et al. Among authors: el kahwaji j.
Gastroenterology. 1995 Nov;109(5):1589-99. doi: 10.1016/0016-5085(95)90648-7.
Gastroenterology. 1995.
PMID: 7557143
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Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy.
Elkahwaji J, Robin MA, Berson A, Tinel M, Lettéron P, Labbe G, Beaune P, Elias D, Rougier P, Escudier B, Duvillard P, Pessayre D.
Elkahwaji J, et al.
Biochem Pharmacol. 1999 Apr 15;57(8):951-4. doi: 10.1016/s0006-2952(98)00372-4.
Biochem Pharmacol. 1999.
PMID: 10086330
Clinical Trial.
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Interleukin-2 overexpresses c-myc and down-regulates cytochrome P-450 in rat hepatocytes.
Tinel M, Elkahwaji J, Robin MA, Fardel N, Descatoire V, Haouzi D, Berson A, Pessayre D.
Tinel M, et al.
J Pharmacol Exp Ther. 1999 May;289(2):649-55.
J Pharmacol Exp Ther. 1999.
PMID: 10215635
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Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA.
Tinel M, Berson A, Elkahwaji J, Cresteil T, Beaune P, Pessayre D.
Tinel M, et al.
J Hepatol. 2003 Aug;39(2):171-8. doi: 10.1016/s0168-8278(03)00238-1.
J Hepatol. 2003.
PMID: 12873812
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Administration of high doses of human recombinant interleukin-2 decreases the expression of several cytochromes P-450 in the rat.
Thal C, el Kahwaji J, Loeper J, Tinel M, Doostzadeh J, Labbe G, Leclaire J, Beaune P, Pessayre D.
Thal C, et al. Among authors: el kahwaji j.
J Pharmacol Exp Ther. 1994 Jan;268(1):515-21.
J Pharmacol Exp Ther. 1994.
PMID: 8301593
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