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Diet-regulated production of PDGFcc by macrophages controls energy storage.
Cox N, Crozet L, Holtman IR, Loyher PL, Lazarov T, White JB, Mass E, Stanley ER, Elemento O, Glass CK, Geissmann F. Cox N, et al. Among authors: elemento o. Science. 2021 Jul 2;373(6550):eabe9383. doi: 10.1126/science.abe9383. Science. 2021. PMID: 34210853 Free PMC article.
QSER1 protects DNA methylation valleys from de novo methylation.
Dixon G, Pan H, Yang D, Rosen BP, Jashari T, Verma N, Pulecio J, Caspi I, Lee K, Stransky S, Glezer A, Liu C, Rivas M, Kumar R, Lan Y, Torregroza I, He C, Sidoli S, Evans T, Elemento O, Huangfu D. Dixon G, et al. Among authors: elemento o. Science. 2021 Apr 9;372(6538):eabd0875. doi: 10.1126/science.abd0875. Science. 2021. PMID: 33833093 Free PMC article.
Pan-cancer analysis reveals molecular patterns associated with age.
Shah Y, Verma A, Marderstein AR, White J, Bhinder B, Garcia Medina JS, Elemento O. Shah Y, et al. Among authors: elemento o. Cell Rep. 2021 Dec 7;37(10):110100. doi: 10.1016/j.celrep.2021.110100. Cell Rep. 2021. PMID: 34879281 Free article.
The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Zhong Y, Alberdi A, Massague J, Sun JC, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F. Deng Z, et al. Among authors: elemento o. Nature. 2024 Feb;626(8000):864-873. doi: 10.1038/s41586-023-06950-4. Epub 2024 Feb 7. Nature. 2024. PMID: 38326607 Free PMC article.
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, Pappin DJ, Dow LE, Papadopoulos N, Gross SS, Cantley LC. Yun J, et al. Among authors: elemento o. Science. 2015 Dec 11;350(6266):1391-6. doi: 10.1126/science.aaa5004. Epub 2015 Nov 5. Science. 2015. PMID: 26541605 Free PMC article.
A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.
He Y, Kim IK, Bian J, Polyzos A, Di Giammartino DC, Zhang YW, Luo J, Hernandez MO, Kedei N, Cam M, Borczuk AC, Lee T, Han Y, Conner EA, Wong M, Tillo DC, Umemura S, Chen V, Ruan L, White JB, Miranda IC, Awasthi PP, Altorki NK, Divakar P, Elemento O, Apostolou E, Giaccone G. He Y, et al. Among authors: elemento o. J Thorac Oncol. 2022 Dec;17(12):1375-1386. doi: 10.1016/j.jtho.2022.08.008. Epub 2022 Aug 30. J Thorac Oncol. 2022. PMID: 36049655 Free PMC article.
BTG1 mutation yields supercompetitive B cells primed for malignant transformation.
Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E, Poh HX, Evans CM, Chadburn A, Chen Z, Shen H, Isles HM, Pelzer B, Tsialta I, Doane AS, Geng H, Rehman MH, Melnick J, Morgan W, Nguyen DTT, Elemento O, Kharas MG, Jaffrey SR, Scott DW, Khelashvili G, Meyer-Hermann M, Victora GD, Melnick A. Mlynarczyk C, et al. Among authors: elemento o. Science. 2023 Jan 20;379(6629):eabj7412. doi: 10.1126/science.abj7412. Epub 2023 Jan 20. Science. 2023. PMID: 36656933 Free PMC article.
468 results