Ellenberger T - Search Results

1

The interaction between polynucleotide kinase phosphatase and the DNA repair protein XRCC1 is critical for repair of DNA alkylation damage and stable association at DNA damage sites.

Della-Maria J, Hegde ML, McNeill DR, Matsumoto Y, Tsai MS, Ellenberger T, Wilson DM 3rd, Mitra S, Tomkinson AE. Della-Maria J, et al. Among authors: ellenberger t. J Biol Chem. 2012 Nov 9;287(46):39233-44. doi: 10.1074/jbc.M112.369975. Epub 2012 Sep 19. J Biol Chem. 2012. PMID: 22992732 Free PMC article.

2

Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes.

Chen X, Pascal J, Vijayakumar S, Wilson GM, Ellenberger T, Tomkinson AE. Chen X, et al. Among authors: ellenberger t. Methods Enzymol. 2006;409:39-52. doi: 10.1016/S0076-6879(05)09003-8. Methods Enzymol. 2006. PMID: 16793394

3

Two DNA-binding and nick recognition modules in human DNA ligase III.

Cotner-Gohara E, Kim IK, Tomkinson AE, Ellenberger T. Cotner-Gohara E, et al. Among authors: ellenberger t. J Biol Chem. 2008 Apr 18;283(16):10764-72. doi: 10.1074/jbc.M708175200. Epub 2008 Jan 30. J Biol Chem. 2008. PMID: 18238776 Free PMC article.

4

Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair.

Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell AD Jr, Tomkinson AE. Chen X, et al. Among authors: ellenberger t. Cancer Res. 2008 May 1;68(9):3169-77. doi: 10.1158/0008-5472.CAN-07-6636. Cancer Res. 2008. PMID: 18451142 Free PMC article.

5

Identification and validation of human DNA ligase inhibitors using computer-aided drug design.

Zhong S, Chen X, Zhu X, Dziegielewska B, Bachman KE, Ellenberger T, Ballin JD, Wilson GM, Tomkinson AE, MacKerell AD Jr. Zhong S, et al. Among authors: ellenberger t. J Med Chem. 2008 Aug 14;51(15):4553-62. doi: 10.1021/jm8001668. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630893 Free PMC article.

6

The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1.

Song W, Pascal JM, Ellenberger T, Tomkinson AE. Song W, et al. Among authors: ellenberger t. DNA Repair (Amst). 2009 Aug 6;8(8):912-9. doi: 10.1016/j.dnarep.2009.05.002. Epub 2009 Jun 11. DNA Repair (Amst). 2009. PMID: 19523882 Free PMC article.

7

An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complex.

Hammel M, Rashid I, Sverzhinsky A, Pourfarjam Y, Tsai MS, Ellenberger T, Pascal JM, Kim IK, Tainer JA, Tomkinson AE. Hammel M, et al. Among authors: ellenberger t. Nucleic Acids Res. 2021 Jan 11;49(1):306-321. doi: 10.1093/nar/gkaa1188. Nucleic Acids Res. 2021. PMID: 33330937 Free PMC article.

8

DNA ligases: structure, reaction mechanism, and function.

Tomkinson AE, Vijayakumar S, Pascal JM, Ellenberger T. Tomkinson AE, et al. Among authors: ellenberger t. Chem Rev. 2006 Feb;106(2):687-99. doi: 10.1021/cr040498d. Chem Rev. 2006. PMID: 16464020 Review. No abstract available.

9

Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining.

Kukshal V, Kim IK, Hura GL, Tomkinson AE, Tainer JA, Ellenberger T. Kukshal V, et al. Among authors: ellenberger t. Nucleic Acids Res. 2015 Aug 18;43(14):7021-31. doi: 10.1093/nar/gkv652. Epub 2015 Jun 29. Nucleic Acids Res. 2015. PMID: 26130724 Free PMC article.

10

Eukaryotic DNA ligases: structural and functional insights.

Ellenberger T, Tomkinson AE. Ellenberger T, et al. Annu Rev Biochem. 2008;77:313-38. doi: 10.1146/annurev.biochem.77.061306.123941. Annu Rev Biochem. 2008. PMID: 18518823 Free PMC article. Review.

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